Import models

Import models from files

The function ~cameo.io.load_model accepts a number of different file formats like SBML (Systems Biology Markup Language) for example.

less data/e_coli_core.xml
from cameo import load_model
model = load_model('data/e_coli_core.xml')
model
Name e_coli_core
Number of metabolites 72
Number of reactions 95
Reactions
acald_c + coa_c + nad_c <=> accoa_c + h_c + nadh_c
acald_e <=> acald_c
ac_c + atp_c <=> actp_c + adp_c
cit_c <=> acon_C_c + h2o_c
acon_C_c + h2o_c <=> icit_c
ac_e + h_e <=> ac_c + h_c
amp_c + atp_c <=> 2.0 adp_c
akg_c + coa_c + nad_c --> co2_c + nadh_c + succoa_c
akg_e + h_e <=> akg_c + h_c
etoh_c + nad_c <=> acald_c + h_c + nadh_c
atp_c + h2o_c --> adp_c + h_c + pi_c
adp_c + 4.0 h_e + pi_c <=> atp_c + h2o_c + 3.0 h_c
1.496 3pg_c + 3.7478 accoa_c + 59.81 atp_c + 0.361 e4p_c + 0.0709 f6p_c + 0.129 g3p_c + 0.205 g6p_c + 0.2557 gln__L_c + 4.9414 glu__L_c + 59.81 h2o_c + 3.547 nad_c + 13.0279 nadph_c + 1.7867 oaa_c + 0.5191 pep_c + 2.8328 pyr_c + 0.8977 r5p_c --> 59.81 adp_c + 4.1182 akg_c + 3.7478 coa_c + 59.81 h_c + 3.547 nadh_c + 13.0279 nadp_c + 59.81 pi_c
co2_e <=> co2_c
accoa_c + h2o_c + oaa_c --> cit_c + coa_c + h_c
2.0 h_c + 0.5 o2_c + q8h2_c --> h2o_c + 2.0 h_e + q8_c
h_e + lac__D_e <=> h_c + lac__D_c
2pg_c <=> h2o_c + pep_c
etoh_e + h_e <=> etoh_c + h_c
ac_e -->
acald_e -->
akg_e -->
co2_e <=>
etoh_e -->
for_e -->
fru_e -->
fum_e -->
glc__D_e <=>
gln__L_e -->
glu__L_e -->
h2o_e <=>
h_e <=>
lac__D_e -->
mal__L_e -->
nh4_e <=>
o2_e <=>
pi_e <=>
pyr_e -->
succ_e -->
fdp_c <=> dhap_c + g3p_c
fdp_c + h2o_c --> f6p_c + pi_c
for_e + h_e --> for_c + h_c
for_c --> for_e
fum_c + q8h2_c --> q8_c + succ_c
fru_e + pep_c --> f6p_c + pyr_c
fum_c + h2o_c <=> mal__L_c
fum_e + 2.0 h_e --> fum_c + 2.0 h_c
g6p_c + nadp_c <=> 6pgl_c + h_c + nadph_c
g3p_c + nad_c + pi_c <=> 13dpg_c + h_c + nadh_c
glc__D_e + pep_c --> g6p_c + pyr_c
atp_c + glu__L_c + nh4_c --> adp_c + gln__L_c + h_c + pi_c
atp_c + gln__L_e + h2o_c --> adp_c + gln__L_c + h_c + pi_c
glu__L_c + h2o_c + nadp_c <=> akg_c + h_c + nadph_c + nh4_c
gln__L_c + h2o_c --> glu__L_c + nh4_c
akg_c + gln__L_c + h_c + nadph_c --> 2.0 glu__L_c + nadp_c
glu__L_e + h_e <=> glu__L_c + h_c
6pgc_c + nadp_c --> co2_c + nadph_c + ru5p__D_c
h2o_e <=> h2o_c
icit_c + nadp_c <=> akg_c + co2_c + nadph_c
icit_c --> glx_c + succ_c
lac__D_c + nad_c <=> h_c + nadh_c + pyr_c
accoa_c + glx_c + h2o_c --> coa_c + h_c + mal__L_c
2.0 h_e + mal__L_e --> 2.0 h_c + mal__L_c
mal__L_c + nad_c <=> h_c + nadh_c + oaa_c
mal__L_c + nad_c --> co2_c + nadh_c + pyr_c
mal__L_c + nadp_c --> co2_c + nadph_c + pyr_c
4.0 h_c + nadh_c + q8_c --> 3.0 h_e + nad_c + q8h2_c
nad_c + nadph_c --> nadh_c + nadp_c
nh4_e <=> nh4_c
o2_e <=> o2_c
coa_c + nad_c + pyr_c --> accoa_c + co2_c + nadh_c
atp_c + f6p_c --> adp_c + fdp_c + h_c
coa_c + pyr_c --> accoa_c + for_c
g6p_c <=> f6p_c
3pg_c + atp_c <=> 13dpg_c + adp_c
6pgl_c + h2o_c --> 6pgc_c + h_c
2pg_c <=> 3pg_c
h_e + pi_e <=> h_c + pi_c
co2_c + h2o_c + pep_c --> h_c + oaa_c + pi_c
atp_c + oaa_c --> adp_c + co2_c + pep_c
atp_c + h2o_c + pyr_c --> amp_c + 2.0 h_c + pep_c + pi_c
accoa_c + pi_c <=> actp_c + coa_c
adp_c + h_c + pep_c --> atp_c + pyr_c
h_e + pyr_e <=> h_c + pyr_c
ru5p__D_c <=> xu5p__D_c
r5p_c <=> ru5p__D_c
2.0 h_e + succ_e --> 2.0 h_c + succ_c
h_e + succ_c --> h_c + succ_e
q8_c + succ_c --> fum_c + q8h2_c
atp_c + coa_c + succ_c <=> adp_c + pi_c + succoa_c
g3p_c + s7p_c <=> e4p_c + f6p_c
2.0 h_e + nadh_c + nadp_c --> 2.0 h_c + nad_c + nadph_c
r5p_c + xu5p__D_c <=> g3p_c + s7p_c
e4p_c + xu5p__D_c <=> f6p_c + g3p_c
dhap_c <=> g3p_c

Other accepted formats include pickle (simply pickled models) and json.

Import models from the internet

In the previous quick start chapter we demonstrated how to use ~cameo.io.load_model to import a model by ID. But where did the model come from? Cameo has currently access to two model repositories on the internet, http://bigg.ucsd.edu and http://darwin.di.uminho.pt/models.

from cameo import models
models.index_models_bigg()
bigg_id gene_count metabolite_count organism reaction_count
0 e_coli_core 137 72 Escherichia coli str. K-12 substr. MG1655 95
1 iAB_RBC_283 346 342 Homo sapiens 469
2 iAF1260 1261 1668 Escherichia coli str. K-12 substr. MG1655 2382
3 iAF1260b 1261 1668 Escherichia coli str. K-12 substr. MG1655 2388
... ... ... ... ... ...
76 iYO844 844 990 Bacillus subtilis subsp. subtilis str. 168 1250
77 iZ_1308 1308 1923 Escherichia coli O157:H7 str. EDL933 2722
78 RECON1 1905 2766 Homo sapiens 3742
79 STM_v1_0 1271 1800 Salmonella enterica subsp. enterica serovar Ty... 2545

80 rows × 5 columns

models.index_models_minho()
id name doi author year formats organism taxonomy validated
0 1 iJR904 10.1186/gb-2003-4-9-r54 Reed 2003 [sbml] Escherichia coli str. K12 substr. MG1655 Bacteria; Proteobacteria; Gammaproteobacteria;... True
1 2 iAF1260 10.1038/msb4100155 Feist 2007 [sbml] Escherichia coli str. K12 substr. MG1655 Bacteria; Proteobacteria; Gammaproteobacteria;... True
2 3 iMM904 10.1186/1752-0509-3-37 Mo 2007 [sbml] Saccharomyces cerevisiae Eukaryota; Opisthokonta; Fungi; Dikarya; Ascom... True
3 4 iJP815 10.1371/journal.pcbi.1000210 Puchalka 2008 [sbml] Pseudomonas putida str. KT2440 Bacteria; Proteobacteria; Gammaproteobacteria;... True
... ... ... ... ... ... ... ... ... ...
144 149 iYali4 10.1038/npjsba.2016.5 Kerkhoven 2016 [sbml] Yarrowia lipolytica Eukaryota; Fungi; Dikarya; Ascomycota; Sacchar... False
145 150 iLB1027_lipid 10.1371/journal.pone.0155038 Jennifer Levering 2016 [sbml] Phaeodactylum tricornutum Eukaryota; Stramenopiles; Bacillariophyta; Bac... True
146 151 iLB1027 10.1371/journal.pone.0155038 Jennifer Levering 2016 [sbml] Phaeodactylum tricornutum Eukaryota; Stramenopiles; Bacillariophyta; Bac... True
147 152 iMT1174 10.1186/s12918-015-0190-y Mohammad Tajparast 2015 [excel] Rhodococcus jostii RHA1 Bacteria; Terrabacteria group; Actinobacteria;... False

148 rows × 9 columns

Models from BiGG and the University of Minho can conveniently be accessd via ~cameo.models.bigg and ~cameo.models.minho respectively.

models.bigg.iJN746
Name iJN746
Number of metabolites 907
Number of reactions 1056
Reactions
cit_e -->
co2_e <=>
1pipdn2c_c + h_c + nadph_c --> Lpipecol_c + nadp_c
2dhglcn_c + atp_c + 2.0 h_c --> 6p2dhglcn_c + adp_c
2dhglcn_p + h_p --> 2dhglcn_c + h_c
2dhglcn_e <=> 2dhglcn_p
34dhcinm_e <=> 34dhcinm_p
34dhcinm_p <=> 34dhcinm_c
34hpp_c + o2_c --> co2_c + hgentis_c
3hdecACP_c + coa_c <=> ACP_c + R_3hdcoa_c
3hddecACP_c + coa_c <=> ACP_c + R_3hddcoa_c
3hcddec5eACP_c + coa_c <=> ACP_c + R_3hcddec5ecoa_c
3hmrsACP_c + coa_c <=> ACP_c + R_3hmrscoa_c
3hcmrs7eACP_c + coa_c <=> ACP_c + R_3hcmrs7ecoa_c
3hhexACP_c + coa_c <=> ACP_c + R_3hhcoa_c
3hoctACP_c + coa_c <=> ACP_c + R_3hocoa_c
3hdecACP_c --> h2o_c + tdec2eACP_c
3hddecACP_c --> h2o_c + tddec2eACP_c
3hcddec5eACP_c --> h2o_c + t3c5ddeceACP_c
3hmrsACP_c --> h2o_c + tmrs2eACP_c
3hcmrs7eACP_c --> h2o_c + t3c7mrseACP_c
3hpalmACP_c --> h2o_c + tpalm2eACP_c
3hcpalm9eACP_c --> h2o_c + t3c9palmeACP_c
3hoctaACP_c --> h2o_c + toctd2eACP_c
3hcvac11eACP_c --> h2o_c + t3c11vaceACP_c
3haACP_c --> but2eACP_c + h2o_c
3hhexACP_c --> h2o_c + thex2eACP_c
3hoctACP_c --> h2o_c + toct2eACP_c
3hibutcoa_c + h2o_c --> 3hmp_c + coa_c + h_c
3mbzalc_c + nad_c --> 3mbzald_c + h_c + nadh_c
3mbzald_c + h2o_c + nad_c --> 2.0 h_c + m_tol_c + nadh_c
3mcat_c + o2_c --> cchoxod_c + h_c
3oxoadp_c + succoa_c --> oxadpcoa_c + succ_c
3odecACP_c + h_c + nadph_c <=> 3hdecACP_c + nadp_c
3oddecACP_c + h_c + nadph_c <=> 3hddecACP_c + nadp_c
3ocddec5eACP_c + h_c + nadph_c --> 3hcddec5eACP_c + nadp_c
3omrsACP_c + h_c + nadph_c <=> 3hmrsACP_c + nadp_c
3ocmrs7eACP_c + h_c + nadph_c --> 3hcmrs7eACP_c + nadp_c
3opalmACP_c + h_c + nadph_c <=> 3hpalmACP_c + nadp_c
3ocpalm9eACP_c + h_c + nadph_c --> 3hcpalm9eACP_c + nadp_c
3ooctdACP_c + h_c + nadph_c <=> 3hoctaACP_c + nadp_c
3ocvac11eACP_c + h_c + nadph_c --> 3hcvac11eACP_c + nadp_c
actACP_c + h_c + nadph_c <=> 3haACP_c + nadp_c
3ohexACP_c + h_c + nadph_c <=> 3hhexACP_c + nadp_c
3ooctACP_c + h_c + nadph_c <=> 3hoctACP_c + nadp_c
h_c + malACP_c + ocACP_c --> 3odecACP_c + ACP_c + co2_c
dcaACP_c + h_c + malACP_c --> 3oddecACP_c + ACP_c + co2_c
cdec3eACP_c + h_c + malACP_c --> 3ocddec5eACP_c + ACP_c + co2_c
ddcaACP_c + h_c + malACP_c --> 3omrsACP_c + ACP_c + co2_c
cddec5eACP_c + h_c + malACP_c --> 3ocmrs7eACP_c + ACP_c + co2_c
h_c + malACP_c + myrsACP_c --> 3opalmACP_c + ACP_c + co2_c
h_c + malACP_c + tdeACP_c --> 3ocpalm9eACP_c + ACP_c + co2_c
h_c + malACP_c + palmACP_c --> 3ooctdACP_c + ACP_c + co2_c
h_c + hdeACP_c + malACP_c --> 3ocvac11eACP_c + ACP_c + co2_c
butACP_c + h_c + malACP_c --> 3ohexACP_c + ACP_c + co2_c
h_c + hexACP_c + malACP_c --> 3ooctACP_c + ACP_c + co2_c
coa_c + oxadpcoa_c --> accoa_c + succoa_c
3oxoadp_e <=> 3oxoadp_p
3oxoadp_p + h_p <=> 3oxoadp_c + h_c
34dhbz_p + h_p <=> 34dhbz_c + h_c
34dhbz_e <=> 34dhbz_p
T4hcinnm_c + atp_c + coa_c --> amp_c + coucoa_c + ppi_c
4cml_c + h_c --> 5odhf2a_c + co2_c
4hbz_c + h_c + nadph_c + o2_c --> 34dhbz_c + h2o_c + nadp_c
4hbz_e <=> 4hbz_p
h2o_c + phthr_c --> 4hthr_c + pi_c
4mbzalc_c + nad_c --> 4mbzald_c + h_c + nadh_c
4mbzald_c + h2o_c + nad_c --> 2.0 h_c + nadh_c + p_tol_c
4mcat_c + o2_c --> h_c + hmccms_c
h_c + oxalc_c --> co2_c + op4en_c
2omcm_c + h_c --> 2hchd_c + co2_c
2hmc_c <=> oxalc_c
hmccm_c <=> 2omcm_c
chols_e -->
6hnac_c + 2.0 h_c + nadh_c + o2_c --> co2_c + dhpyr_c + h2o_c + nad_c
h2o_c + h_c + thp2c_c <=> L2aadp6sa_c
L2aadp6sa_c + h2o_c + nad_c --> L2aadp_c + 2.0 h_c + nadh_c
2oxoadp_c + glu__L_c <=> L2aadp_c + akg_c
4abut_c + akg_c <=> glu__L_c + sucsal_c
4abut_p + h_p --> 4abut_c + h_c
4abut_e <=> 4abut_p
2.0 accoa_c <=> aacoa_c + coa_c
acald_c + coa_c + nad_c <=> accoa_c + h_c + nadh_c
adocbip_c + gtp_c + h_c --> agdpcbi_c + ppi_c
accoa_c + atp_c + hco3_c <=> adp_c + h_c + malcoa_c + pi_c
acglu_c + atp_c --> acg5p_c + adp_c
accoa_c + glu__L_c --> acglu_c + coa_c + h_c
2obut_c + h_c + pyr_c --> 2ahbut_c + co2_c
ac_c + atp_c <=> actp_c + adp_c
h_c + 2.0 pyr_c --> alac__S_c + co2_c
btcoa_c + fad_c <=> b2coa_c + fadh2_c
fad_c + hxcoa_c <=> fadh2_c + hx2coa_c
fad_c + occoa_c <=> fadh2_c + oc2coa_c
dcacoa_c + fad_c <=> dc2coa_c + fadh2_c
ddcacoa_c + fad_c <=> dd2coa_c + fadh2_c
fad_c + tdcoa_c <=> fadh2_c + td2coa_c
fad_c + pmtcoa_c <=> fadh2_c + hdd2coa_c
2mbcoa_c + fad_c --> 2mb2coa_c + fadh2_c
2.0 ibcoa_c + o2_c --> 2.0 2mp2coa_c + 2.0 h2o_c
ACP_c + accoa_c <=> acACP_c + coa_c
acorn_c + h2o_c --> ac_c + orn_c
acon_C_e <=> acon_C_p
cit_c <=> icit_c
cit_c <=> acon_C_c + h2o_c
acon_C_c + h2o_c <=> icit_c
acorn_c + akg_c <=> acg5sa_c + glu__L_c
atp_c + coa_c + ppa_c --> amp_c + ppcoa_c + ppi_c
ac_c + atp_c + coa_c <=> accoa_c + amp_c + ppi_c
ac_p + h_p --> ac_c + h_c
ac_e <=> ac_p
adn_c + h2o_c + h_c --> ins_c + nh4_c
4adcho_c --> 4abz_c + h_c + pyr_c
adcobhex_c + appl_c + atp_c --> adocbi_c + adp_c + h_c + pi_c
adcobhex_c + applp_c + atp_c --> adocbip_c + adp_c + h_c + pi_c
adcobdam_c + 4.0 atp_c + 4.0 gln__L_c + 4.0 h2o_c --> adcobhex_c + 4.0 adp_c + 4.0 glu__L_c + 4.0 h_c + 4.0 pi_c
amp_c + atp_c <=> 2.0 adp_c
atp_c --> camp_c + ppi_c
adocbi_c + atp_c --> adocbip_c + adp_c + h_c
agdpcbi_c + rdmbzi_c --> adocbl_c + gmp_c + h_c
ade_c + prpp_c --> amp_c + ppi_c
aicar_c + ppi_c <=> C04051_c + prpp_c
dcamp_c <=> amp_c + fum_c
25aics_c <=> aicar_c + fum_c
asp__L_c + atp_c --> 4pasp_c + adp_c
asp__L_c + gtp_c + imp_c --> dcamp_c + gdp_c + 2.0 h_c + pi_c
agm_c + h2o_c --> ptrc_c + urea_c
1ddecg3p_c + ddcaACP_c --> ACP_c + pa120_c
1hdecg3p_c + palmACP_c --> ACP_c + pa160_c
1hdec9eg3p_c + hdeACP_c --> ACP_c + pa161_c
1odecg3p_c + ocdcaACP_c --> ACP_c + pa180_c
1odec11eg3p_c + octeACP_c --> ACP_c + pa181_c
acg5sa_c + nadp_c + pi_c <=> acg5p_c + h_c + nadph_c
10fthf_c + aicar_c <=> fprica_c + thf_c
air_c + co2_c <=> 5aizc_c + h_c
akg_c + coa_c + nad_c --> co2_c + nadh_c + succoa_c
akg_c + h_c + lpam_c <=> co2_c + sdhlam_c
coa_c + sdhlam_c <=> dhlam_c + succoa_c
akg_p + h_p <=> akg_c + h_c
akg_e <=> akg_p
2.0 ala__D_c + atp_c <=> adp_c + alaala_c + h_c + pi_c
ala__L_c <=> ala__D_c
akg_c + ala__L_c <=> glu__L_c + pyr_c
ala__L_c + atp_c + trnaala_c --> alatrna_c + amp_c + ppi_c
ala__L_e <=> ala__L_p
glyald_c + h_c + nadh_c <=> glyc_c + nad_c
acald_c + h_c + nadh_c --> etoh_c + nad_c
etoh_c + pqq_c --> acald_c + pqqh2_c
acald_c + h2o_c + nad_c --> ac_c + 2.0 h_c + nadh_c
acald_c + h2o_c + nad_c <=> ac_c + 2.0 h_c + nadh_c
air_c + h2o_c + nad_c --> 4ampm_c + 2.0 for_c + 3.0 h_c + nadh_c
amp_c + h2o_c --> ade_c + r5p_c
anth_c + prpp_c --> ppi_c + pran_c
chor_c + gln__L_c --> anth_c + glu__L_c + h_c + pyr_c
6a2ohxnt_c <=> 1pipdn2c_c + h2o_c
ap4a_c + h2o_c --> 2.0 adp_c + 2.0 h_c
5apentam_c + h2o_c --> 5aptn_c + nh3_c
5apru_c + h_c + nadph_c --> 5aprbu_c + nadp_c
aps_c + trdrd_c --> amp_c + 2.0 h_c + so3_c + trdox_c
5aptn_c + akg_c <=> glu__L_c + oxptn_c
arg__L_c + h2o_c --> citr__L_c + nh4_c
arg__L_c + h_c --> agm_c + co2_c
arg__L_p + orn_c <=> arg__L_c + orn_p
argsuc_c <=> arg__L_c + fum_c
asp__L_c + atp_c + citr__L_c --> amp_c + argsuc_c + h_c + ppi_c
arg__L_c + atp_c + trnaarg_c --> amp_c + argtrna_c + ppi_c
arg__L_p + atp_c + h2o_c --> adp_c + arg__L_c + h_c + pi_c
arg__L_e <=> arg__L_p
arg__L_c + pyr_c <=> 5g2oxpt_c + ala__L_c
4pasp_c + h_c + nadph_c --> aspsa_c + nadp_c + pi_c
asn__L_c + h2o_c --> asp__L_c + nh4_c
asp__L_c + atp_c + gln__L_c + h2o_c --> amp_c + asn__L_c + glu__L_c + h_c + ppi_c
asp__L_c + cbp_c --> cbasp_c + h_c + pi_c
asp__L_c + h2o_c + o2_c --> h2o2_c + nh4_c + oaa_c
asp__L_c + o2_c --> h2o2_c + h_c + iasp_c
asp__L_c --> fum_c + nh4_c
akg_c + asp__L_c <=> glu__L_c + oaa_c
asp__L_c + atp_c + trnaasp_c --> amp_c + asptrna_c + ppi_c
asp__L_p + atp_c + h2o_c --> adp_c + asp__L_c + h_c + pi_c
asp__L_p + 2.0 h_p --> asp__L_c + 2.0 h_c
asp__L_e <=> asp__L_p
arg__L_c + succoa_c --> coa_c + h_c + sucarg_c
atp_c + prpp_c <=> ppi_c + prbatp_c
adp_c + 4.0 h_p + pi_c <=> atp_c + h2o_c + 3.0 h_c
bhb_c + nad_c <=> acac_c + h_c + nadh_c
betald_c + h2o_c + nad_c --> glyb_c + 2.0 h_c + nadh_c
glyb_c + hcys__L_c --> dmgly_c + met__L_c
bz_c + h_c + nadh_c + o2_c --> bz12diol_c + nad_c
bzalc_c + nad_c --> bzal_c + h_c + nadh_c
bzal_c + h2o_c + nad_c --> bz_c + 2.0 h_c + nadh_c
bz12diol_c + nad_c --> catechol_c + co2_c + nadh_c
bz_p + h_p <=> bz_c + h_c
bz_e <=> bz_p
0.05 5mthf_c + 5e-05 accoa_c + 0.488 ala__L_c + 0.001 amp_c + 0.281 arg__L_c + 0.229 asn__L_c + 0.229 asp__L_c + 45.7318 atp_c + 6e-06 coa_c + 0.0005 cpe160_c + 0.0005 cpe180_c + 0.0005 cpg160_c + 0.0005 cpg180_c + 0.126 ctp_c + 0.087 cys__L_c + 0.0247 datp_c + 0.0254 dctp_c + 0.0254 dgtp_c + 0.0247 dttp_c + 1e-05 fad_c + 0.25 gln__L_c + 0.25 glu__L_c + 0.582 gly_c + 0.203 gtp_c + 45.5608 h2o_c + 0.0005 hemeO_c + 0.09 his__L_c + 0.276 ile__L_c + 0.428 leu__L_c + 0.326 lys__L_c + 0.146 met__L_c + 0.00215 nad_c + 5e-05 nadh_c + 0.00013 nadp_c + 0.0004 nadph_c + 0.0005 pe120_c + 0.0005 pe160_c + 0.0005 pe161_c + 0.0005 pe180_c + 0.0005 pe181_c + 0.0005 pg120_c + 0.0005 pg160_c + 0.0005 pg180_c + 0.176 phe__L_c + 0.21 pro__L_c + 0.035 ptrc_c + 0.205 ser__L_c + 0.0005 sheme_c + 3e-06 succoa_c + 0.241 thr__L_c + 0.054 trp__L_c + 0.131 tyr__L_c + 0.003 udpg_c + 0.136 utp_c + 0.402 val__L_c --> 45.5608 adp_c + 45.56035 h_c + 45.5628 pi_c + 0.7302 ppi_c
caffcoa_c + h2o_c --> 34dhbald_c + accoa_c
34dhcinm_c + atp_c + coa_c --> amp_c + caffcoa_c + ppi_c
2.0 h2o2_c --> 2.0 h2o_c + o2_c
catechol_c + o2_c --> 2hmcnsad_c
catechol_c + o2_c --> ccmuac_c + 2.0 h_c
catechol_e <=> catechol_p
catechol_p <=> catechol_c
atp_c + co2_c + nh4_c <=> adp_c + cbp_c + 2.0 h_c
2.0 atp_c + gln__L_c + h2o_c + hco3_c --> 2.0 adp_c + cbp_c + glu__L_c + 2.0 h_c + pi_c
4c2me_c + atp_c --> 2p4c2me_c + adp_c + h_c
2.0 amet_c + pe161_c --> 2.0 ahcys_c + cpe160_c + 2.0 h_c
2.0 amet_c + pg161_c --> 2.0 ahcys_c + cpg160_c + 2.0 h_c
2.0 amet_c + pe181_c --> 2.0 ahcys_c + cpe180_c + 2.0 h_c
2.0 amet_c + pg181_c --> 2.0 ahcys_c + cpg180_c + 2.0 h_c
atp_c + chol_p + h2o_c --> adp_c + chol_c + h_c + pi_c
chol_p + h_p --> chol_c + h_c
chol_e <=> chol_p
chol_c + nad_c --> betald_c + h_c + nadh_c
chols_c + h2o_c --> chol_c + h_c + so4_c
chols_e <=> chols_p
26dap_LL_c <=> 26dap__M_c
atp_c + chols_p + h2o_c --> adp_c + chols_c + h_c + pi_c
chor_c --> pphn_c
3psme_c --> chor_c + pi_c
cit_p + h_p <=> cit_c + h_c
cit_e <=> cit_p
2.0 pg120_p <=> clpn120_p + glyc_p
2.0 pg160_p <=> clpn160_p + glyc_p
2.0 pg161_p <=> clpn161_p + glyc_p
2.0 pg180_p <=> clpn180_p + glyc_p
2.0 pg181_p <=> clpn181_p + glyc_p
co2_e <=> co2_p
co2_p <=> co2_c
confrl_c + nad_c --> conialdh_c + h_c + nadh_c
conialdh_c + h2o_c + nad_c --> fer_c + 2.0 h_c + nadh_c
cobalt2_e <=> cobalt2_p
cobalt2_p --> cobalt2_c
atp_c + cobalt2_c + h2o_c + hgbam_c --> adp_c + co2dam_c + 2.0 h_c + pi_c
coucoa_c + h2o_c --> 4hbald_c + accoa_c
confrl_e <=> confrl_p
confrl_p <=> confrl_c
cpppg3_c + 2.0 h_c + o2_c --> 2.0 co2_c + 2.0 h2o_c + pppg9_c
2.0 amet_c + cpppg3_c --> 2.0 co2_c + 2.0 dad_5_c + 2.0 met__L_c + pppg9_c
atp_c + crn_p + h2o_c --> adp_c + crn_c + h_c + pi_c
crn_e <=> crn_p
accoa_c + h2o_c + oaa_c --> cit_c + coa_c + h_c
csn_c + h2o_c + h_c --> nh4_c + ura_c
atp_c + gln__L_c + h2o_c + utp_c --> adp_c + ctp_c + glu__L_c + 2.0 h_c + pi_c
2.0 ficytc_c + 2.0 h_c + q8h2_c --> 2.0 focytc_c + 2.0 h_p + q8_c
2.0 focytc_c + 0.5 o2_c --> 2.0 ficytc_c + h2o_c
atp_c + co1dam_c + h_c --> adcobdam_c + pppi_c
2.0 co2dam_c + nadh_c --> 2.0 co1dam_c + h_c + nad_c
acser_c + h2s_c --> ac_c + cys__L_c + h_c
acser_c + tsul_c --> ac_c + scys__L_c
cyst__L_c + h2o_c <=> 2obut_c + cys__L_c + nh4_c
cyst__L_c + h2o_c --> hcys__L_c + nh4_c + pyr_c
atp_c + cys__L_c + trnacys_c --> amp_c + cystrna_c + ppi_c
atp_c + cys__L_p + h2o_c --> adp_c + cys__L_c + h_c + pi_c
cys__L_e <=> cys__L_p
2.0 h_c + 0.5 o2_c + q8h2_c --> h2o_c + 2.0 h_p + q8_c
4.0 h_c + 0.5 o2_c + q8h2_c --> h2o_c + 4.0 h_p + q8_c
atp_c + cmp_c <=> adp_c + cdp_c
atp_c + dcmp_c <=> adp_c + dcdp_c
ala__D_c + fad_c + h2o_c --> fadh2_c + nh4_c + pyr_c
24dab_c + akg_c + 2.0 h_c <=> aspsa_c + glu__L_c
dad_2_c + h2o_c + h_c --> din_c + nh4_c
atp_c + damp_c <=> adp_c + dadp_c
15dap_c + akg_c --> glu__L_c + h2o_c + h_c + pprdn_c
26dap__M_c + h_c --> co2_c + lys__L_c
ctp_c + h_c + pa120_c --> cdpdddecg_c + ppi_c
ctp_c + h_c + pa160_c --> cdpdhdecg_c + ppi_c
ctp_c + h_c + pa161_c --> cdpdhdec9eg_c + ppi_c
ctp_c + h_c + pa180_c --> cdpdodecg_c + ppi_c
ctp_c + h_c + pa181_c --> cdpdodec11eg_c + ppi_c
ru5p__D_c --> db4p_c + for_c + h_c
dca_e <=> dca_p
dctp_c + h2o_c + h_c --> dutp_c + nh4_c
ctp_c + h2o_c + h_c --> nh4_c + utp_c
ddca_e <=> ddca_p
e4p_c + h2o_c + pep_c --> 2dda7p_c + pi_c
atp_c + dgmp_c <=> adp_c + dgdp_c
dh3mchc_c + nad_c --> 3mcat_c + co2_c + nadh_c
dh4mchc_c + nad_c --> 4mcat_c + co2_c + nadh_c
23dhmb_c --> 3mob_c + h2o_c
23dhmp_c --> 3mop_c + h2o_c
23dhdp_c + h_c + nadph_c --> nadp_c + thdp_c
aspsa_c + pyr_c --> 23dhdp_c + 2.0 h2o_c + h_c
dhf_c + h_c + nadph_c <=> nadp_c + thf_c
atp_c + dhpt_c + glu__L_c --> adp_c + dhf_c + h_c + pi_c
dhnpt_c --> 2ahhmp_c + gcald_c + h_c
dhor__S_c + o2_c <=> h2o2_c + orot_c
dhor__S_c + h2o_c <=> cbasp_c + h_c
2dhphaccoa_c + coa_c + 2.0 h2o_c --> 3hadpcoa_c + accoa_c + h2_c + h_c
56dura_c + h2o_c --> cala_c + h_c
25dhpp_c + h2o_c + h_c --> 5apru_c + nh4_c
dhbpt_c + h_c + nadh_c --> nad_c + thbpt_c
2ahhmp_c + 4abz_c --> dhpt_c + h2o_c
3dhq_c <=> 3dhsk_c + h2o_c
2dda7p_c --> 3dhq_c + pi_c
3dhsk_c --> 34dhbz_c + h2o_c
akg_c + lys__D_c <=> 6a2ohxnt_c + glu__D_c
lys__D_c + pyr_c <=> 6a2ohxnt_c + ala__D_c
dmpp_c + ipdp_c --> grdp_c + ppi_c
dmgly_c + fad_c + h2o_c <=> fadh2_c + fald_c + sarcs_c
aacald_c -->
C100mclPHA_c -->
C120mclPHA_c -->
C121mclPHA_c -->
C140mclPHA_c -->
C141mclPHA_c -->
C60mclPHA_c -->
C80mclPHA_c -->
dad_5_c -->
fald_c -->
mclPHA_c -->
ptal_c -->
amet_c + dna_c <=> ahcys_c + dna5mtc_c + h_c
dhpmp_c + h2o_c --> dhnpt_c + pi_c
ahdt_c + h2o_c --> dhpmp_c + h_c + ppi_c
atp_c + dpcoa_c --> adp_c + coa_c + h_c
C100mclPHA_c + coa_c --> R_3hdcoa_c + mclPHAg_c
C120mclPHA_c + coa_c --> R_3hddcoa_c + mclPHAg_c
C121mclPHA_c + coa_c --> R_3hcddec5ecoa_c + mclPHAg_c
C140mclPHA_c + coa_c --> R_3hmrscoa_c + mclPHAg_c
C141mclPHA_c + coa_c --> R_3hcmrs7ecoa_c + mclPHAg_c
C60mclPHA_c + coa_c --> R_3hhcoa_c + mclPHAg_c
C80mclPHA_c + coa_c --> R_3hocoa_c + mclPHAg_c
2dhp_c + h_c + nadph_c --> nadp_c + pant__R_c
atp_c + dtmp_c <=> adp_c + dtdp_c
56dura_c + nadp_c <=> h_c + nadph_c + ura_c
dutp_c + h2o_c --> dump_c + h_c + ppi_c
dxyl5p_c + h_c + nadph_c --> 2me4p_c + nadp_c
g3p_c + h_c + pyr_c --> co2_c + dxyl5p_c
h_p + lac__D_p <=> h_c + lac__D_c
lac__D_e <=> lac__D_p
e4p_c + h2o_c + nad_c <=> 4per_c + 2.0 h_c + nadh_c
h_c + nadph_c + tdec2eACP_c --> dcaACP_c + nadp_c
h_c + nadph_c + tddec2eACP_c --> ddcaACP_c + nadp_c
h_c + nadph_c + t3c5ddeceACP_c --> cddec5eACP_c + nadp_c
h_c + nadph_c + tmrs2eACP_c --> myrsACP_c + nadp_c
h_c + nadph_c + t3c7mrseACP_c --> nadp_c + tdeACP_c
h_c + nadph_c + tpalm2eACP_c --> nadp_c + palmACP_c
h_c + nadph_c + t3c9palmeACP_c --> hdeACP_c + nadp_c
h_c + nadph_c + toctd2eACP_c --> nadp_c + ocdcaACP_c
h_c + nadph_c + t3c11vaceACP_c --> nadp_c + octeACP_c
but2eACP_c + h_c + nadph_c --> butACP_c + nadp_c
h_c + nadph_c + thex2eACP_c --> hexACP_c + nadp_c
h_c + nadph_c + toct2eACP_c --> nadp_c + ocACP_c
3hbcoa_c <=> b2coa_c + h2o_c
2mp2coa_c + h2o_c --> 3hibutcoa_c
3hhcoa_c <=> h2o_c + hx2coa_c
3hocoa_c <=> h2o_c + oc2coa_c
3hdcoa_c <=> dc2coa_c + h2o_c
3hddcoa_c <=> dd2coa_c + h2o_c
3htdcoa_c <=> h2o_c + td2coa_c
3hhdcoa_c <=> h2o_c + hdd2coa_c
2mb2coa_c + h2o_c --> 3hmbcoa_c
2ddg6p_c --> g3p_c + pyr_c
6pgc_c --> 2ddg6p_c + h2o_c
2pg_c <=> h2o_c + pep_c
atp_c + ethso3_p + h2o_c --> adp_c + ethso3_c + h_c + pi_c
ethso3_e <=> ethso3_p
2ddglcn_e -->
2dhglcn_e -->
34dhbz_e -->
34dhcinm_e -->
3oxoadp_e -->
4abut_e -->
4hbz_e -->
T4hcinnm_e -->
ac_e -->
acon_C_e -->
akg_e -->
ala__L_e -->
arg__L_e -->
asp__L_e -->
bz_e -->
catechol_e -->
chol_e -->
cobalt2_e <=>
confrl_e -->
crn_e -->
cys__L_e -->
dca_e -->
ddca_e -->
ethso3_e -->
fe2_e <=>
fer_e -->
fru_e -->
fum_e -->
ga_e -->
glc__D_e <=>
glcn_e -->
glu__L_e -->
gly_e -->
glyald_e -->
glyb_e -->
glyc_e -->
glyclt_e -->
h2_e <=>
h2o_e <=>
h_e <=>
hco3_e <=>
hdca_e -->
his__L_e -->
hxa_e -->
icit_e -->
ile__L_e -->
isetac_e -->
lac__D_e -->
lac__L_e -->
leu__L_e -->
lys__L_e -->
m_xyl_e -->
mal__L_e -->
met__L_e -->
mso3_e -->
na1_e <=>
nac_e -->
nh4_e <=>
ni2_e -->
no2_e -->
o2_e <=>
octa_e -->
orn_e -->
p_xyl_e -->
pac_e -->
pentso3_e -->
phe__L_e -->
pi_e <=>
pro__L_e -->
ptrc_e -->
quin_e -->
rib__D_e -->
ser__L_e -->
so4_e <=>
spmd_e -->
succ_e -->
taur_e -->
thr__L_e -->
tol_e -->
tsul_e -->
ttdca_e -->
tyr__L_e -->
val__L_e -->
vanln_e -->
vanlt_e -->
atp_c + coa_c + dca_p + h_p --> amp_c + dcacoa_c + h_c + ppi_c
atp_c + coa_c + ddca_p + h_p --> amp_c + ddcacoa_c + h_c + ppi_c
atp_c + coa_c + h_p + ttdca_p --> amp_c + h_c + ppi_c + tdcoa_c
atp_c + coa_c + h_p + hdca_p --> amp_c + h_c + pmtcoa_c + ppi_c
atp_c + coa_c + h_p + hxa_p --> amp_c + h_c + hxcoa_c + ppi_c
atp_c + coa_c + h_p + octa_p --> amp_c + h_c + occoa_c + ppi_c
2.0 fald_c + 2.0 focytc_c + o2_c --> 2.0 cytcc_c + 2.0 for_c + 4.0 h_c
fdp_c <=> dhap_c + g3p_c
fdp_c + h2o_c --> f6p_c + pi_c
fe2_c + ppp9_c --> 2.0 h_c + pheme_c
ferulcoa_c + h2o_c --> accoa_c + vanln_c
for_c + nad_c --> co2_c + nadh_c
fmnh2_c + isetac_c + o2_c --> fmn_c + gcald_c + h2o_c + h_c + so3_c
fmnh2_c + mso3_c + o2_c --> fald_c + fmn_c + h2o_c + h_c + so3_c
ethso3_c + fmnh2_c + o2_c --> acald_c + fmn_c + h2o_c + h_c + so3_c
fmnh2_c + o2_c + pentso3_c --> fmn_c + h2o_c + h_c + ptal_c + so3_c
fmnh2_c + o2_c + taur_c --> aacald_c + fmn_c + h2o_c + h_c + so3_c
atp_c + fe2_e + h2o_c --> adp_c + fe2_c + h_c + pi_c
fe2_e <=> fe2_c
atp_c + coa_c + fer_c --> amp_c + ferulcoa_c + ppi_c
fer_e <=> fer_p
fer_p <=> fer_c
10fthf_c + mettrna_c --> fmettrna_c + h_c + thf_c
atp_c + fmn_c + h_c --> fad_c + ppi_c
fmn_c + h_c + nadph_c --> fmnh2_c + nadp_c
2ahhmd_c + 4abz_c --> dhpt_c + ppi_c
forglu_c + h2o_c + 2.0 h_c --> Nforglu_c + nh3_c
atp_c + f1p_c <=> adp_c + fdp_c + h_c
fru_e + pep_c --> f1p_c + pyr_c
10fthf_c + h2o_c --> for_c + h_c + thf_c
fum_c + h2o_c <=> mal__L_c
4fumacac_c + h2o_c --> acac_c + fum_c + h_c
fum_p + 2.0 h_p --> fum_c + 2.0 h_c
fum_e <=> fum_p
accoa_c + gam1p_c --> acgam1p_c + coa_c + h_c
glu1sa_c --> 5aop_c
ddcaACP_c + glyc3p_c --> 1ddecg3p_c + ACP_c
glyc3p_c + palmACP_c --> 1hdecg3p_c + ACP_c
glyc3p_c + hdeACP_c --> 1hdec9eg3p_c + ACP_c
glyc3p_c + ocdcaACP_c --> 1odecg3p_c + ACP_c
glyc3p_c + octeACP_c --> 1odec11eg3p_c + ACP_c
fad_c + glyc3p_c --> dhap_c + fadh2_c
glyc3p_c + nadp_c <=> dhap_c + h_c + nadph_c
glu5sa_c <=> 1pyr5c_c + h2o_c + h_c
glu5p_c + h_c + nadph_c --> glu5sa_c + nadp_c + pi_c
g6p_B_c + nadp_c --> 6pgl_c + h_c + nadph_c
g6p_c + nadp_c --> 6pgl_c + h_c + nadph_c
g6p_c <=> g6p_B_c
ga_c + o2_c --> 2.0 h_c + omaketo_c
fad_c + glcn_p <=> 2dhglcn_p + fadh2_c
g1p_c + h_c + utp_c <=> ppi_c + udpg_c
g3p_c + nad_c + pi_c <=> 13dpg_c + h_c + nadh_c
10fthf_c + gar_c <=> fgam_c + h_c + thf_c
atp_c + for_c + gar_c --> adp_c + fgam_c + h_c + pi_c
ga_e <=> ga_p
ga_p + h_p <=> ga_c + h_c
gcald_c + h2o_c + nad_c --> glyclt_c + 2.0 h_c + nadh_c
gdbtal_c + h2o_c + nad_c --> 4gudbutn_c + 2.0 h_c + nadh_c
f6p_c + gln__L_c --> gam6p_c + glu__L_c
ser__L_c + thf_c <=> gly_c + h2o_c + mlthf_c
atp_c + gmp_c <=> adp_c + gdp_c
glc__D_p + h2o_p + q8_c --> glcn_p + h_p + q8h2_c
glcn_p + h_p <=> glcn_c + h_c
glcn_e <=> glcn_p
atp_c + coa_c + glutar_c --> adp_c + glutcoa_c + pi_c
S_gtrdhdlp_c + coa_c --> dhlam_c + glutcoa_c
atp_c + glc__D_p + h2o_c --> adp_c + glc__D_c + h_c + pi_c
glc__D_e <=> glc__D_p
atp_c + glu__L_c + nh4_c --> adp_c + gln__L_c + h_c + pi_c
atp_c + gln__L_c + glutrna_gln_c + h2o_c --> adp_c + glntrna_c + glu__L_c + h_c + pi_c
atp_c + gln__L_c + trnagln_c --> amp_c + glntrna_c + ppi_c
atp_c + glu__L_c --> adp_c + glu5p_c
atp_c + cys__L_c + glu__L_c --> adp_c + glucys_c + h_c + pi_c
glu__L_c + h_c --> 4abut_c + co2_c
glu__L_c + h2o_c + nadp_c <=> akg_c + h_c + nadph_c + nh4_c
gln__L_c + h2o_c --> glu__L_c + nh4_c
gln__L_c + h2o_c + prpp_c --> glu__L_c + ppi_c + pram_c
glu__D_c <=> glu__L_c
akg_c + gln__L_c + h_c + nadph_c --> 2.0 glu__L_c + nadp_c
fad_c + glutcoa_c + h_c --> b2coa_c + co2_c + fadh2_c
glutrna_c + h_c + nadph_c --> glu1sa_c + nadp_c + trnaglu_c
atp_c + glu__L_c + trnaglu_c --> amp_c + glutrna_c + ppi_c
atp_c + glu__L_p + h2o_c --> adp_c + glu__L_c + h_c + pi_c
glu__L_p + na1_p --> glu__L_c + na1_c
glu__L_e <=> glu__L_p
2.0 glx_c + h_c --> 2h3oppan_c + co2_c
glyald_c + h2o_c + nad_c <=> glyc__R_c + 2.0 h_c + nadh_c
glyald_e <=> glyald_p
glyald_p <=> glyald_c
atp_c + glyb_p + h2o_c --> adp_c + glyb_c + h_c + pi_c
glyb_e <=> glyb_p
atp_c + glyc__R_c --> 3pg_c + adp_c + h_c
gly_c + nad_c + thf_c --> co2_c + mlthf_c + nadh_c + nh4_c
glyclt_p + h_p <=> glyclt_c + h_c
glyclt_e <=> glyclt_p
co2_c + mlthf_c + nadh_c + nh4_c --> gly_c + nad_c + thf_c
glyclt_c + o2_c --> glx_c + h2o2_c
glyc_e <=> glyc_p
glyc_c <=> glyc_p
h_c + hpyr_c + nadh_c <=> glyc__R_c + nad_c
atp_c + glyc_c --> adp_c + glyc3p_c + h_c
atp_c + gly_c + trnagly_c --> amp_c + glytrna_c + ppi_c
atp_c + gly_p + h2o_c <=> adp_c + gly_c + h_c + pi_c
gly_e <=> gly_p
atp_c + gln__L_c + h2o_c + xmp_c --> amp_c + glu__L_c + gmp_c + 2.0 h_c + ppi_c
6pgc_c + nadp_c --> co2_c + nadph_c + ru5p__D_c
atp_c + glcn_c --> 6pgc_c + adp_c + h_c
gsn_c + h2o_c --> gua_c + rib__D_c
grdp_c + ipdp_c --> frdp_c + ppi_c
gthox_c + h_c + nadph_c --> 2.0 gthrd_c + nadp_c
2.0 gthrd_c + h2o2_c <=> gthox_c + 2.0 h2o_c
atp_c + glucys_c + gly_c --> adp_c + gthrd_c + h_c + pi_c
gtp_c + h2o_c --> ahdt_c + for_c + h_c
gtp_c + 3.0 h2o_c --> 25dhpp_c + for_c + 2.0 h_c + ppi_c
gdptp_c + h2o_c <=> h_c + pi_c + ppgpp_c
atp_c + gtp_c --> amp_c + gdptp_c + h_c
gua_c + h2o_c + h_c --> nh4_c + xan_c
gua_c + prpp_c --> gmp_c + ppi_c
4gudbutn_c + h2o_c --> 4abut_c + urea_c
co2_c + h2o_c <=> h2co3_c
h_c + hco3_c <=> h2co3_c
h2o_e <=> h2o_p
h2o_p <=> h2o_c
h2_e <=> h2_p
h2_p <=> h2_c
3hbcoa_c + nad_c --> aacoa_c + h_c + nadh_c
3hhcoa_c + nad_c --> 3ohcoa_c + h_c + nadh_c
3hocoa_c + nad_c --> 3oocoa_c + h_c + nadh_c
3hdcoa_c + nad_c --> 3odcoa_c + h_c + nadh_c
3hddcoa_c + nad_c --> 3oddcoa_c + h_c + nadh_c
3htdcoa_c + nad_c --> 3otdcoa_c + h_c + nadh_c
3hhdcoa_c + nad_c --> 3ohdcoa_c + h_c + nadh_c
3hmbcoa_c + nad_c <=> 2maacoa_c + h_c + nadh_c
3hadpcoa_c --> h2_c + oxadpcoa_c
co2_c + h2o_c <=> h_c + hco3_c
hco3_e + na1_e <=> hco3_c + na1_c
hdca_e <=> hdca_p
frdp_c + h2o_c + pheme_c --> hemeO_c + ppi_c
atp_c + glc__D_c --> adp_c + g6p_c + h_c
hgentis_c + o2_c --> 4mlacac_c + h_c
3hmp_c + nad_c --> h_c + mmtsa_c + nadh_c
his__L_c --> nh4_c + urcan_c
h2o_c + histd_c + 2.0 nad_c --> 3.0 h_c + his__L_c + 2.0 nadh_c
h2o_c + hisp_c --> histd_c + pi_c
atp_c + his__L_c + trnahis_c --> amp_c + histrna_c + ppi_c
atp_c + h2o_c + his__L_p --> adp_c + h_c + his__L_c + pi_c
his__L_e <=> his__L_p
h2o_c + 4.0 ppbng_c --> hmbil_c + 4.0 nh4_c
hmgcoa_c --> acac_c + accoa_c
4ahmmp_c + atp_c --> 4ampm_c + adp_c + h_c
2hmcnsad_c + h2o_c + nad_c --> 2hmc_c + 3.0 h_c + nadh_c
h2o_c + hmccms_c + nad_c --> 2.0 h_c + hmccm_c + nadh_c
2hmcnsad_c + h2o_c --> for_c + 2.0 h_c + op4en_c
h2o_c + hmccms_c --> 2hchd_c + for_c + h_c
cchoxod_c + h2o_c --> ac_c + h_c + op4en_c
4h2opntn_c --> acald_c + pyr_c
4hoxoh_c --> ppal_c + pyr_c
4h2opntn_c --> acald_c + pyr_c
2ahhmp_c + atp_c --> 2ahhmd_c + amp_c + h_c
hpyr_c <=> 2h3oppan_c
hom__L_c + nad_c <=> aspsa_c + h_c + nadh_c
accoa_c + hom__L_c <=> achms_c + coa_c
atp_c + hom__L_c --> adp_c + h_c + phom_c
glu__L_c + imacp_c <=> akg_c + hisp_c
h2o_c + hxan_c + nad_c --> h_c + nadh_c + xan_c
hxa_e <=> hxa_p
hxan_c + prpp_c --> imp_c + ppi_c
h_e <=> h_p
icit_c + nadp_c <=> akg_c + co2_c + nadph_c
h_p + icit_p <=> h_c + icit_c
icit_e <=> icit_p
icit_c --> glx_c + succ_c
gln__L_c + prlp_c --> aicar_c + eig3p_c + glu__L_c + h_c
eig3p_c --> h2o_c + imacp_c
2cpr5p_c + h_c --> 3ig3p_c + co2_c + h2o_c
akg_c + ile__L_c <=> 3mop_c + glu__L_c
atp_c + ile__L_c + trnaile_c --> amp_c + iletrna_c + ppi_c
atp_c + h2o_c + ile__L_p --> adp_c + h_c + ile__L_c + pi_c
ile__L_e <=> ile__L_p
h2o_c + imp_c <=> fprica_c
h2o_c + imp_c + nad_c --> h_c + nadh_c + xmp_c
h2o_c + ins_c --> hxan_c + rib__D_c
ipdp_c <=> dmpp_c
h2mb4p_c + h_c + nadh_c --> h2o_c + ipdp_c + nad_c
3c2hmp_c + nad_c <=> 3c4mop_c + h_c + nadh_c
3c2hmp_c <=> 2ippm_c + h2o_c
2ippm_c + h2o_c <=> 3c3hmp_c
3mob_c + accoa_c + h2o_c --> 3c3hmp_c + coa_c + h_c
atp_c + h2o_c + isetac_p --> adp_c + h_c + isetac_c + pi_c
isetac_e <=> isetac_p
4izp_c + h2o_c --> forglu_c + h_c
23dhmb_c + nadp_c <=> alac__S_c + h_c + nadph_c
2ahbut_c + h_c + nadph_c <=> 23dhmp_c + nadp_c
acACP_c + h_c + malACP_c --> ACP_c + actACP_c + co2_c
accoa_c + h_c + malACP_c --> actACP_c + co2_c + coa_c
aacoa_c + coa_c --> 2.0 accoa_c
3ohcoa_c + coa_c --> accoa_c + btcoa_c
3oocoa_c + coa_c --> accoa_c + hxcoa_c
3odcoa_c + coa_c --> accoa_c + occoa_c
3oddcoa_c + coa_c --> accoa_c + dcacoa_c
3otdcoa_c + coa_c --> accoa_c + ddcacoa_c
3ohdcoa_c + coa_c --> accoa_c + tdcoa_c
lac__D_c + nad_c <=> h_c + nadh_c + pyr_c
akg_c + leu__L_c <=> 4mop_c + glu__L_c
atp_c + leu__L_c + trnaleu_c --> amp_c + leutrna_c + ppi_c
atp_c + h2o_c + leu__L_p --> adp_c + h_c + leu__L_c + pi_c
leu__L_e <=> leu__L_p
Lpipecol_c + o2_c --> h2o2_c + h_c + thp2c_c
h_c + lys__L_c --> 15dap_c + co2_c
lys__L_c + o2_c --> 5apentam_c + co2_c + h2o_c + h_c
lys__L_c <=> lys__D_c
atp_c + lys__L_c + trnalys_c --> amp_c + lystrna_c + ppi_c
atp_c + h2o_c + lys__L_p --> adp_c + h_c + lys__L_c + pi_c
lys__L_e <=> lys__L_p
lac__L_c + q8_c --> pyr_c + q8h2_c
h_p + lac__L_p <=> h_c + lac__L_c
lac__L_e <=> lac__L_p
4mlacac_c --> 4fumacac_c
2maacoa_c + coa_c --> accoa_c + ppcoa_c
h_c + malACP_c --> acACP_c + co2_c
male_c <=> fum_c
h2o_c + malm_c --> h_c + male_c + nh3_c
accoa_c + glx_c + h2o_c --> coa_c + h_c + mal__L_c
2.0 h_p + mal__L_p --> 2.0 h_c + mal__L_c
mal__L_e <=> mal__L_p
fad_c + ivcoa_c --> 3mb2coa_c + fadh2_c
3mb2coa_c + atp_c + hco3_c --> 3mgcoa_c + adp_c + h_c + pi_c
2mcit_c --> 2mcacn_c + h2o_c
micit_c <=> pyr_c + succ_c
h2o_c + oaa_c + ppcoa_c --> 2mcit_c + coa_c + h_c
ACP_c + malcoa_c <=> coa_c + malACP_c
mal__L_c + nad_c <=> h_c + nadh_c + oaa_c
mal__L_c + q8_c --> oaa_c + q8h2_c
mal__L_c + nad_c --> co2_c + nadh_c + pyr_c
2mecdp_c + h_c --> h2mb4p_c + h2o_c
2p4c2me_c --> 2mecdp_c + cmp_c
2me4p_c + ctp_c + h_c --> 4c2me_c + ppi_c
achms_c + h2s_c <=> ac_c + h_c + hcys__L_c
atp_c + h2o_c + met__L_c --> amet_c + pi_c + ppi_c
h2o_c + met__L_c --> 2obut_c + ch4s_c + nh4_c
5mthf_c + hcys__L_c <=> h_c + met__L_c + thf_c
atp_c + met__L_c + trnamet_c --> amp_c + mettrna_c + ppi_c
atp_c + h2o_c + met__L_p --> adp_c + h_c + met__L_c + pi_c
met__L_e <=> met__L_p
3mgcoa_c + h2o_c --> hmgcoa_c
2mcacn_c + h2o_c <=> micit_c
coa_c + mmtsa_c + nad_c --> co2_c + nadh_c + ppcoa_c
3mob_c + h2o_c + mlthf_c --> 2dhp_c + thf_c
atp_c + h2o_c + mso3_p --> adp_c + h_c + mso3_c + pi_c
mso3_e <=> mso3_p
ch4s_c + 3.0 h2o_c + 3.0 nadp_c <=> 4.0 h_c + mso3_c + 3.0 nadph_c
h2o_c + methf_c <=> 10fthf_c + h_c
mlthf_c + nadp_c <=> methf_c + nadph_c
2.0 h_c + mlthf_c + nadph_c --> 5mthf_c + nadp_c
hcys__L_c + mhpglu_c <=> hpglu_c + met__L_c
h_c + m_tol_c + nadh_c + o2_c --> dh3mchc_c + nad_c
ccmuac_c + h_c <=> mucl_c
CCbuttc_c + h_c --> 4cml_c
mucl_c <=> 5odhf2a_c
h_c + m_xyl_c + nadh_c + o2_c --> 3mbzalc_c + h2o_c + nad_c
m_xyl_p <=> m_xyl_c
m_xyl_e <=> m_xyl_p
nac_c + 0.5 o2_c --> 6hnac_c
h_p + nac_p <=> h_c + nac_c
nac_e <=> nac_p
4.0 h_c + nadh_c + q8_c --> 3.0 h_p + nad_c + q8h2_c
h_c + nadh_c + q8_c --> nad_c + q8h2_c
atp_c + nad_c --> adp_c + h_c + nadp_c
h_c + nadph_c + q8_c --> nadp_c + q8h2_c
atp_c + dnad_c + gln__L_c + h2o_c --> amp_c + glu__L_c + h_c + nad_c + ppi_c
atp_c + h2o_c + nac_c + prpp_c --> adp_c + nicrnt_c + pi_c + ppi_c
3.0 h_p + 2.0 na1_c --> 3.0 h_c + 2.0 na1_p
2.0 h_p + na1_c --> 2.0 h_c + na1_p
na1_e <=> na1_p
atp_c + gdp_c <=> adp_c + gtp_c
atp_c + udp_c <=> adp_c + utp_c
atp_c + cdp_c <=> adp_c + ctp_c
atp_c + dtdp_c <=> adp_c + dttp_c
atp_c + dgdp_c <=> adp_c + dgtp_c
atp_c + dudp_c <=> adp_c + dutp_c
atp_c + dcdp_c <=> adp_c + dctp_c
atp_c + dadp_c <=> adp_c + datp_c
h2o_c + nfmalm_c --> for_c + h_c + malm_c
Nforglu_c + h2o_c --> for_c + glu__L_c + 2.0 h_c
nh4_e <=> nh4_p
nh4_p <=> nh4_c
ni2_e <=> ni2_p
atp_c + h2o_c + ni2_p --> adp_c + h_c + ni2_c + pi_c
atp_c + h_c + nicrnt_c <=> dnad_c + ppi_c
dmbzid_c + nicrnt_c --> 5prdmbz_c + h_c + nac_c
2.0 h_c + prpp_c + quln_c --> co2_c + nicrnt_c + ppi_c
h_p + no2_p <=> h_c + no2_c
no2_e <=> no2_p
h2o_c + xmp_c --> pi_c + xtsn_c
h2o_p + xmp_p --> pi_p + xtsn_p
h2o_c + imp_c --> ins_c + pi_c
h2o_p + imp_p --> ins_p + pi_p
h2o_c + ump_c --> pi_c + uri_c
h2o_p + ump_p --> pi_p + uri_p
dcmp_c + h2o_c --> dcyt_c + pi_c
dcmp_p + h2o_p --> dcyt_p + pi_p
cmp_c + h2o_c --> cytd_c + pi_c
cmp_p + h2o_p --> cytd_p + pi_p
dtmp_c + h2o_c --> pi_c + thymd_c
dtmp_p + h2o_p --> pi_p + thymd_p
damp_c + h2o_c --> dad_2_c + pi_c
damp_p + h2o_p --> dad_2_p + pi_p
amp_c + h2o_c --> adn_c + pi_c
amp_p + h2o_p --> adn_p + pi_p
dgmp_c + h2o_c --> dgsn_c + pi_c
dgmp_p + h2o_p --> dgsn_p + pi_p
gmp_c + h2o_c --> gsn_c + pi_c
gmp_p + h2o_p --> gsn_p + pi_p
5.0 h_c + 3.0 nadh_c + no2_c --> 2.0 h2o_c + 3.0 nad_c + nh4_c
o2_e <=> o2_p
o2_p <=> o2_c
h_c + oaa_c --> co2_c + pyr_c
5g2oxpt_c + h_c --> co2_c + gdbtal_c
2obut_c + coa_c + nad_c --> co2_c + nadh_c + ppcoa_c
oca_c --> oaa_c + pyr_c
cbp_c + orn_c <=> citr__L_c + h_c + pi_c
acac_c + succoa_c --> aacoa_c + succ_c
octa_e <=> octa_p
glu__L_c + ohpb_c <=> akg_c + phthr_c
4mop_c + coa_c + nad_c <=> co2_c + ivcoa_c + nadh_c
3mob_c + coa_c + nad_c --> co2_c + ibcoa_c + nadh_c
3mop_c + coa_c + nad_c --> 2mbcoa_c + co2_c + nadh_c
h2o_c + omaenol_c --> oca_c
omaketo_c <=> omaenol_c
3c4mop_c + h_c --> 4mop_c + co2_c
h_c + orot5p_c --> co2_c + ump_c
h2o_c + op4en_c --> 4h2opntn_c
2hchd_c + h2o_c --> 4hoxoh_c
h2o_c + op4en_c --> 4h2opntn_c
orn_c --> nh4_c + pro__L_c
h_c + orn_c --> co2_c + ptrc_c
acorn_c + glu__L_c <=> acglu_c + orn_c
atp_c + h2o_c + orn_p --> adp_c + h_c + orn_c + pi_c
orn_e <=> orn_p
orot5p_c + ppi_c <=> orot_c + prpp_c
2oxoadp_c + h_c + lpam_c --> S_gtrdhdlp_c + co2_c
5odhf2a_c + h2o_c --> 3oxoadp_c + h_c
h2o_c + nad_c + oxptn_c <=> glutar_c + 2.0 h_c + nadh_c
1pyr5c_c + 2.0 h2o_c + nad_c --> glu__L_c + h_c + nadh_c
1pyr5c_c + 2.0 h_c + nadph_c --> nadp_c + pro__L_c
chor_c + nh4_c --> 4adcho_c + h2o_c
atp_c + coa_c + pac_c <=> amp_c + phaccoa_c + ppi_c
na1_p + pac_p <=> na1_c + pac_c
pac_e <=> pac_p
ala_B_c + atp_c + pant__R_c --> amp_c + h_c + pnto__R_c + ppi_c
udcpp_c + ugmda_c --> uagmda_c + ump_c
atp_c + hco3_c + pyr_c --> adp_c + h_c + oaa_c + pi_c
amet_c + pre4_c --> ahcys_c + h_c + pre5_c
amet_c + pre3b_c --> ahcys_c + 3.0 h_c + pre4_c
amet_c + dscl_c --> ahcys_c + h_c + pre3a_c
h_c + nadph_c + pre6a_c --> nadp_c + pre6b_c
2.0 amet_c + pre6b_c --> 2.0 ahcys_c + co2_c + 2.0 h_c + pre8_c
h_c + pre8_c --> hgbyr_c
34dhbz_c + o2_c --> CCbuttc_c + 2.0 h_c
coa_c + nad_c + pyr_c --> accoa_c + co2_c + nadh_c
h_c + lpam_c + pyr_c --> adhlam_c + co2_c
adhlam_c + coa_c <=> accoa_c + dhlam_c
dhlam_c + nad_c <=> h_c + lpam_c + nadh_c
o2_c + pdx5p_c --> h2o2_c + pydx5p_c
dxyl5p_c + nad_c + phthr_c --> co2_c + 2.0 h2o_c + h_c + nadh_c + pdx5p_c + pi_c
h2o_c + pdx5p_c --> pi_c + pydxn_c
atp_c + h2o_c + pe120_c --> adp_c + h_c + pe120_p + pi_c
atp_c + h2o_c + pe160_c --> adp_c + h_c + pe160_p + pi_c
atp_c + h2o_c + pe161_c --> adp_c + h_c + pe161_p + pi_c
atp_c + h2o_c + pe180_c --> adp_c + h_c + pe180_p + pi_c
atp_c + h2o_c + pe181_c --> adp_c + h_c + pe181_p + pi_c
pentso3_e <=> pentso3_p
4per_c + nad_c <=> h_c + nadh_c + ohpb_c
gam1p_c <=> gam6p_c
3pg_c + nad_c <=> 3php_c + h_c + nadh_c
g6p_c <=> f6p_c
3pg_c + atp_c <=> 13dpg_c + adp_c
6pgl_c + h2o_c --> 6pgc_c + h_c
6p2dhglcn_c + nadph_c <=> 6pgc_c + 2.0 h_c + nadp_c
2pg_c <=> 3pg_c
g1p_c <=> g6p_c
atp_c + h2o_c + pgp120_c --> adp_c + h_c + pgp120_p + pi_c
atp_c + h2o_c + pgp160_c --> adp_c + h_c + pgp160_p + pi_c
atp_c + h2o_c + pgp161_c --> adp_c + h_c + pgp161_p + pi_c
atp_c + h2o_c + pgp180_c --> adp_c + h_c + pgp180_p + pi_c
atp_c + h2o_c + pgp181_c --> adp_c + h_c + pgp181_p + pi_c
h2o_c + pgp120_c --> pg120_c + pi_c
h2o_p + pgp120_p --> pg120_p + pi_p
h2o_c + pgp160_c --> pg160_c + pi_c
h2o_p + pgp160_p --> pg160_p + pi_p
h2o_c + pgp161_c --> pg161_c + pi_c
h2o_p + pgp161_p --> pg161_p + pi_p
h2o_c + pgp180_c --> pg180_c + pi_c
h2o_p + pgp180_p --> pg180_p + pi_p
h2o_c + pgp181_c --> pg181_c + pi_c
h2o_p + pgp181_p --> pg181_p + pi_p
cdpdddecg_c + glyc3p_c --> cmp_c + h_c + pgp120_c
cdpdhdecg_c + glyc3p_c --> cmp_c + h_c + pgp160_c
cdpdhdec9eg_c + glyc3p_c --> cmp_c + h_c + pgp161_c
cdpdodecg_c + glyc3p_c --> cmp_c + h_c + pgp180_c
cdpdodec11eg_c + glyc3p_c --> cmp_c + h_c + pgp181_c
C100mclPHA_c + C120mclPHA_c + C60mclPHA_c + C80mclPHA_c <=> mclPHA_c
h2_c + o2_c + phaccoa_c --> 2dhphaccoa_c
R_3hdcoa_c + mclPHAg_c --> C100mclPHA_c + coa_c
R_3hddcoa_c + mclPHAg_c --> C120mclPHA_c + coa_c
R_3hcddec5ecoa_c + mclPHAg_c --> C121mclPHA_c + coa_c
R_3hmrscoa_c + mclPHAg_c --> C140mclPHA_c + coa_c
R_3hcmrs7ecoa_c + mclPHAg_c --> C141mclPHA_c + coa_c
R_3hhcoa_c + mclPHAg_c --> C60mclPHA_c + coa_c
R_3hocoa_c + mclPHAg_c --> C80mclPHA_c + coa_c
akg_c + phe__L_c <=> glu__L_c + phpyr_c
o2_c + phe__L_c + thbpt_c --> dhbpt_c + h2o_c + tyr__L_c
atp_c + phe__L_c + trnaphe_c --> amp_c + phetrna_c + ppi_c
h_p + phe__L_p <=> h_c + phe__L_c
phe__L_e <=> phe__L_p
h_p + pi_p <=> h_c + pi_c
pi_e <=> pi_p
atp_c + h2o_c + pi_p --> adp_c + h_c + 2.0 pi_c
5aprbu_c + h2o_c --> 4r5au_c + pi_c
4ampm_c + atp_c --> 2mahmp_c + adp_c
atp_c + pnto__R_c --> 4ppan_c + adp_c + h_c
h2o_c + ppi_c --> h_c + 2.0 pi_c
2.0 5aop_c --> 2.0 h2o_c + h_c + ppbng_c
co2_c + h2o_c + pep_c --> h_c + oaa_c + pi_c
4ppcys_c + h_c --> co2_c + pan4p_c
h2o_c + ppgpp_c --> gdp_c + ppi_c
atp_c + ppi_c <=> adp_c + pppi_c
r1p_c <=> r5p_c
4ppan_c + ctp_c + cys__L_c --> 4ppcys_c + cdp_c + h_c + pi_c
nad_c + pphn_c --> 34hpp_c + co2_c + nadh_c
h_c + pphn_c --> co2_c + h2o_c + phpyr_c
1.5 o2_c + pppg9_c --> 3.0 h2o_c + ppp9_c
2.0 h2o_c + nad_c + pprdn_c --> 5aptn_c + h_c + nadh_c
atp_c + h2o_c + pyr_c --> amp_c + 2.0 h_c + pep_c + pi_c
uaagmda_c --> h_c + peptido_kt_c + udcpdp_c
atp_c + gly_c + pram_c --> adp_c + gar_c + h_c + pi_c
pran_c <=> 2cpr5p_c
atp_c + fpram_c --> adp_c + air_c + 2.0 h_c + pi_c
h2o_c + prbamp_c --> prfp_c
5aizc_c + asp__L_c + atp_c <=> 25aics_c + adp_c + h_c + pi_c
h2o_c + prbatp_c --> h_c + ppi_c + prbamp_c
atp_c + fgam_c + gln__L_c + h2o_c --> adp_c + fpram_c + glu__L_c + h_c + pi_c
prfp_c --> prlp_c
fad_c + pro__L_c --> 1pyr5c_c + fadh2_c + h_c
atp_c + pro__L_c + trnapro_c --> amp_c + ppi_c + protrna_c
atp_c + h2o_c + pro__L_p --> adp_c + h_c + pi_c + pro__L_c
h_p + pro__L_p --> h_c + pro__L_c
na1_p + pro__L_p --> na1_c + pro__L_c
pro__L_e <=> pro__L_p
atp_c + r5p_c <=> amp_c + h_c + prpp_c
pep_c + skm5p_c <=> 3psme_c + pi_c
h_c + ps120_c --> co2_c + pe120_c
h_c + ps160_c --> co2_c + pe160_c
h_c + ps161_c --> co2_c + pe161_c
h_c + ps180_c --> co2_c + pe180_c
h_c + ps181_c --> co2_c + pe181_c
3php_c + glu__L_c <=> akg_c + pser__L_c
h2o_c + pser__L_c --> pi_c + ser__L_c
cdpdddecg_c + ser__L_c --> cmp_c + h_c + ps120_c
cdpdhdecg_c + ser__L_c --> cmp_c + h_c + ps160_c
cdpdhdec9eg_c + ser__L_c --> cmp_c + h_c + ps161_c
cdpdodecg_c + ser__L_c --> cmp_c + h_c + ps180_c
cdpdodec11eg_c + ser__L_c --> cmp_c + h_c + ps181_c
accoa_c + pi_c <=> actp_c + coa_c
h_c + nadh_c + o2_c + p_tol_c --> dh4mchc_c + nad_c
atp_c + h_c + pan4p_c <=> dpcoa_c + ppi_c
atp_c + h2o_c + ptrc_p --> adp_c + h_c + pi_c + ptrc_c
ptrc_e <=> ptrc_p
h_c + nadh_c + o2_c + p_xyl_c --> 4mbzalc_c + h2o_c + nad_c
h2o_c + pydx5p_c --> pi_c + pydx_c
adp_c + h_c + pep_c --> atp_c + pyr_c
pi_c + uri_c <=> r1p_c + ura_c
dhpyr_c + o2_c --> h_c + nfmalm_c
p_xyl_p <=> p_xyl_c
p_xyl_e <=> p_xyl_p
pqq_c + quin_c --> 3dhq_c + pqqh2_c
quin_e <=> quin_p
h_p + quin_p <=> h_c + quin_c
dhap_c + iasp_c --> 2.0 h2o_c + pi_c + quln_c
h_c + 0.5 o2_c + pre3a_c --> pre3b_c
amet_c + h2o_c + pre5_c --> ac_c + ahcys_c + h_c + pre6a_c
2.0 atp_c + 2.0 gln__L_c + h2o_c + hgbyr_c --> 2.0 adp_c + 2.0 glu__L_c + h_c + hgbam_c + ppi_c
atp_c + r15bp_c --> adp_c + prpp_c
atp_c + r1p_c --> adp_c + h_c + r15bp_c
atp_c + ribflv_c --> adp_c + fmn_c + h_c
4r5au_c + db4p_c --> dmlz_c + 2.0 h2o_c + pi_c
2.0 dmlz_c --> 4r5au_c + ribflv_c
atp_c + rib__D_c <=> adp_c + h_c + r5p_c
3odcoa_c + h_c + nadph_c <=> R_3hdcoa_c + nadp_c
3oddcoa_c + h_c + nadph_c <=> R_3hddcoa_c + nadp_c
3otdcoa_c + h_c + nadph_c <=> R_3hmrscoa_c + nadp_c
3ohcoa_c + h_c + nadph_c <=> R_3hhcoa_c + nadp_c
3oocoa_c + h_c + nadph_c <=> R_3hocoa_c + nadp_c
atp_c + h2o_c + rib__D_p --> adp_c + h_c + pi_c + rib__D_c
rib__D_e <=> rib__D_p
nadh_c + rbrdxOX_c <=> h_c + nad_c + rbrdxRD_c
adp_c + trdrd_c --> dadp_c + h2o_c + trdox_c
gdp_c + trdrd_c --> dgdp_c + h2o_c + trdox_c
cdp_c + trdrd_c --> dcdp_c + h2o_c + trdox_c
trdrd_c + udp_c --> dudp_c + h2o_c + trdox_c
ru5p__D_c <=> xu5p__D_c
r5p_c <=> ru5p__D_c
5prdmbz_c + h2o_c --> pi_c + rdmbzi_c
2.0 h2o_c + 2.0 h_c + sucarg_c --> co2_c + 2.0 nh4_c + sucorn_c
atp_c + h_c + so4_c --> aps_c + ppi_c
h2o_c + o2_c + sarcs_c --> fald_c + gly_c + h2o2_c
2.0 gthrd_c + scys__L_c <=> cys__L_c + gthox_c + h_c + so3_c
h2o_c + sl26da_c --> 26dap_LL_c + succ_c
akg_c + sl26da_c <=> glu__L_c + sl2a6o_c
atp_c + h2o_c + selmeth_c --> pi_c + ppi_c + seasmet_c
accoa_c + ser__L_c <=> acser_c + coa_c
ser__L_c <=> nh4_c + pyr_c
atp_c + ser__L_c + trnaser_c --> amp_c + ppi_c + sertrna_c
ser__L_c <=> h_c + nh3_c + pyr_c
h_p + ser__L_p <=> h_c + ser__L_c
ser__L_e <=> ser__L_p
h2o_c + sucglu_c --> glu__L_c + succ_c
h2o_c + nad_c + sucgsa_c --> 2.0 h_c + nadh_c + sucglu_c
dscl_c + nad_c --> h_c + nadh_c + scl_c
fe2_c + scl_c --> 3.0 h_c + sheme_c
3dhsk_c + h_c + nadph_c <=> nadp_c + skm_c
atp_c + skm_c --> adp_c + h_c + skm5p_c
cys__L_c + suchms_c --> cyst__L_c + h_c + succ_c
h2s_c + suchms_c <=> h_c + hcys__L_c + succ_c
h2o_c + suchms_c <=> 2obut_c + h_c + nh4_c + succ_c
2.0 na1_e + so4_e <=> 2.0 na1_c + so4_c
so4_e <=> so4_p
akg_c + sucorn_c --> glu__L_c + sucgsa_c
atp_c + h2o_c + spmd_p --> adp_c + h_c + pi_c + spmd_c
spmd_e <=> spmd_p
ametam_c + ptrc_c --> 5mta_c + h_c + spmd_c
h2o_c + nadp_c + sucsal_c <=> 2.0 h_c + nadph_c + succ_c
2.0 h_p + succ_p --> 2.0 h_c + succ_c
succ_e <=> succ_p
fad_c + succ_c <=> fadh2_c + fum_c
q8_c + succ_c --> fum_c + q8h2_c
atp_c + coa_c + succ_c <=> adp_c + pi_c + succoa_c
5.0 h_c + 3.0 nadph_c + so3_c --> 3.0 h2o_c + h2s_c + 3.0 nadp_c
atp_c + h2o_c + so4_p --> adp_c + h_c + pi_c + so4_c
tdec2eACP_c <=> cdec3eACP_c
T4hcinnm_e <=> T4hcinnm_p
T4hcinnm_p <=> T4hcinnm_c
g3p_c + s7p_c <=> e4p_c + f6p_c
akg_c + o2_c + taur_c --> aacald_c + co2_c + h_c + so3_c + succ_c
atp_c + h2o_c + taur_p --> adp_c + h_c + pi_c + taur_c
taur_e <=> taur_p
nad_c + nadph_c <=> nadh_c + nadp_c
h2o_c + succoa_c + thdp_c --> coa_c + sl2a6o_c
athr__L_c <=> acald_c + gly_c
thr__L_c <=> acald_c + gly_c
thr__L_c --> 2obut_c + nh4_c
h2o_c + phom_c --> pi_c + thr__L_c
atp_c + thr__L_c + trnathr_c --> amp_c + ppi_c + thrtrna_c
atp_c + h2o_c + thr__L_p --> adp_c + h_c + pi_c + thr__L_c
thr__L_e <=> thr__L_p
r5p_c + xu5p__D_c <=> g3p_c + s7p_c
e4p_c + xu5p__D_c <=> f6p_c + g3p_c
dump_c + mlthf_c --> dhf_c + dtmp_c
tol_e <=> tol_p
tol_p <=> tol_c
dhap_c <=> g3p_c
h_c + nadph_c + trdox_c --> nadp_c + trdrd_c
3ig3p_c + ser__L_c <=> g3p_c + h2o_c + trp__L_c
indole_c + ser__L_c --> h2o_c + trp__L_c
3ig3p_c <=> g3p_c + indole_c
2h3oppan_c + h_c + nadh_c <=> glyc__R_c + nad_c
atp_c + h2o_c + tsul_p --> adp_c + h_c + pi_c + tsul_c
tsul_e <=> tsul_p
ttdca_e <=> ttdca_p
akg_c + tyr__L_c <=> 34hpp_c + glu__L_c
atp_c + trnatyr_c + tyr__L_c --> amp_c + ppi_c + tyrtrna_c
h_p + tyr__L_p <=> h_c + tyr__L_c
tyr__L_e <=> tyr__L_p
26dap__M_c + atp_c + uamag_c --> adp_c + h_c + pi_c + ugmd_c
pep_c + uacgam_c --> pi_c + uaccg_c
acgam1p_c + h_c + utp_c --> ppi_c + uacgam_c
uacgam_c + uagmda_c --> h_c + uaagmda_c + udp_c
atp_c + glu__D_c + uama_c --> adp_c + h_c + pi_c + uamag_c
ala__L_c + atp_c + uamr_c --> adp_c + h_c + pi_c + uama_c
h_c + nadph_c + uaccg_c --> nadp_c + uamr_c
h2o_c + udcpdp_c --> h_c + pi_c + udcpp_c
alaala_c + atp_c + ugmd_c --> adp_c + h_c + pi_c + ugmda_c
4hbz_p + h_p <=> 4hbz_c + h_c
atp_c + ump_c <=> adp_c + udp_c
2kmb_c + glu__L_c --> akg_c + met__L_c
2.0 amet_c + uppg3_c --> 2.0 ahcys_c + dscl_c + h_c
hmbil_c --> h2o_c + uppg3_c
4.0 h_c + uppg3_c --> 4.0 co2_c + cpppg3_c
4.0 h_c + uppg1_c --> 4.0 co2_c + cpppg1_c
cala_c + h2o_c + 2.0 h_c --> ala_B_c + co2_c + nh4_c
prpp_c + ura_c --> ppi_c + ump_c
h2o_c + urcan_c --> 4izp_c
h2o_c + 2.0 h_c + urea_c --> co2_c + 2.0 nh4_c
akg_c + val__L_c <=> 3mob_c + glu__L_c
atp_c + trnaval_c + val__L_c --> amp_c + ppi_c + valtrna_c
atp_c + h2o_c + val__L_p --> adp_c + h_c + pi_c + val__L_c
val__L_e <=> val__L_p
h_p + vanlt_p <=> h_c + vanlt_c
vanln_e <=> vanln_p
vanlt_e <=> vanlt_p
h2o_c + nad_c + vanln_c --> 2.0 h_c + nadh_c + vanlt_c
4hbald_c + h2o_c + nad_c --> 4hbz_c + 2.0 h_c + nadh_c
34dhbald_c + h2o_c + nad_c --> 34dhbz_c + 2.0 h_c + nadh_c
h_p + vanln_p <=> h_c + vanln_c
h_c + nadh_c + o2_c + vanlt_c --> 34dhbz_c + fald_c + h2o_c + nad_c
h2o_c + nad_c + xan_c --> h_c + nadh_c + urate_c
h_c + nadh_c + o2_c + tol_c --> bzalc_c + h2o_c + nad_c
h2o_c + xtsn_c --> rib__D_c + xan_c
atp_c + h2o_c + pentso3_p --> adp_c + h_c + pentso3_c + pi_c
mhpglu_c <=>
dna5mtc_c <=>
dna_c <=>
mclPHAg_c <=>
pqq_c <=>
pqqh2_c <=>
hpglu_c <=>
models.minho.iMM904
Name iMM904
Number of metabolites 1228
Number of reactions 1577
Reactions
13BDglcn_c + h2o_c --> glc_D_c
13BDglcn_e + h2o_e --> glc_D_e
udpg_c --> 13BDglcn_c + h_c + udp_c
udpg_c --> 16BDglcn_c + h_c + udp_c
23camp_c + h2o_c + h_c --> amp2p_c
2dda7p_c <=> 2dda7p_m
2dhp_c <=> 2dhp_m
2doxg6p_c + h2o_c --> 2dglc_c + pi_c
2hb_c + nad_c <=> 2obut_c + h_c + nadh_c
2hb_e + h_e <=> 2hb_c + h_c
2hpmhmbq_m + amet_m --> ahcys_m + h_m + q6_m
2hp6mp_m + o2_m --> 2hp6mbq_m + h2o_m
2hp6mbq_m + amet_m --> 2hpmmbq_m + ahcys_m + h_m
2hpmmbq_m + 0.5 o2_m --> 2hpmhmbq_m
2mbac_c --> 2mbac_e
2mbald_c <=> 2mbald_e
2mbald_c <=> 2mbald_m
2mbtoh_c <=> 2mbtoh_e
2mbtoh_c <=> 2mbtoh_m
2mppal_c <=> 2mppal_e
2mppal_c <=> 2mppal_m
2obut_c <=> 2obut_m
2oxoadp_m --> 2oxoadp_c
2phetoh_e <=> 2phetoh_c
2phetoh_m <=> 2phetoh_c
34hpp_m + h_m + nadh_m --> 34hpl_m + nad_m
34hpp_c + o2_c --> co2_c + hgentis_c
34hpp_c + h_c <=> 34hpp_m + h_m
34hpp_c + h_c <=> 34hpp_x + h_x
3c3hmp_c <=> 3c3hmp_e
3c3hmp_c <=> 3c3hmp_m
3c4mop_c <=> 3c4mop_m
3dh5hpb_m + amet_m --> 3hph5mb_m + ahcys_m + h_m
3dh5hpb_c <=> 3dh5hpb_m
3dsphgn_c + h_c + nadph_c --> nadp_c + sphgn_c
3hanthrn_c + o2_c --> cmusa_c + h_c
3hph5mb_m --> 2hp6mp_m + co2_m
3c2hmp_c + amet_c --> 3ipmmest_c + ahcys_c
3mbald_c <=> 3mbald_e
3mbald_c <=> 3mbald_m
3mob_c + h_c --> 2mppal_c + co2_c
3mob_c <=> 3mob_m
3mop_c + h_c --> 2mbald_c + co2_c
3mop_e <=> 3mop_c
3mop_c <=> 3mop_m
3ophb_5_c + 0.5 o2_c --> 3dh5hpb_c
3ophb_5_c <=> 3ophb_5_m
4abutn_c <=> 4abutn_m
4abut_c <=> 4abut_m
4abz_c <=> 4abz_e
4abz_c <=> 4abz_m
4h2oglt_c <=> 4h2oglt_m
4h2oglt_c <=> 4h2oglt_x
coa_m + coucoa_m + h2o_m + nad_m --> 4hbzcoa_m + accoa_m + h_m + nadh_m
4hbzcoa_m + h2o_m --> 4hbz_m + coa_m + h_m
4hbz_c <=> 4hbz_m
4hglusa_m + h2o_m + nad_m <=> e4hglu_m + 2.0 h_m + nadh_m
4hpro_LT_c <=> 4hpro_LT_m
h2o_c + phthr_c --> 4hthr_c + pi_c
4mop_c + h_c --> 3mbald_c + co2_c
5aop_e + h_e --> 5aop_c + h_c
5aop_c <=> 5aop_m
6pgl_c <=> 6pgl_r
8aonn_e + h_e <=> 8aonn_c + h_c
4aabutn_c + h2o_c --> 4abut_c + ac_c
aact_c + h2o_c + o2_c --> h2o2_c + mthgxl_c + nh4_c
L2aadp_c + atp_c + h_c + nadph_c --> L2aadp6sa_c + amp_c + nadp_c + ppi_c
L2aadp_c + atp_c + h_c + nadh_c --> L2aadp6sa_c + amp_c + nad_c + ppi_c
2oxoadp_c + glu_L_c <=> L2aadp_c + akg_c
4abut_c + akg_c --> glu_L_c + sucsal_c
abt_e <=> abt_c
4abutn_m + h2o_m + nad_m --> 4abut_m + 2.0 h_m + nadh_m
4abut_e + h_e <=> 4abut_c + h_c
2.0 accoa_c --> aacoa_c + coa_c
2.0 accoa_m --> aacoa_m + coa_m
3odcoa_x + coa_x --> accoa_x + occoa_x
3oddcoa_x + coa_x --> accoa_x + dcacoa_x
3otdcoa_x + coa_x --> accoa_x + ddcacoa_x
3ohdcoa_x + coa_x --> accoa_x + tdcoa_x
3ohodcoa_x + coa_x --> accoa_x + pmtcoa_x
3ohxccoa_x + coa_x --> accoa_x + ttccoa_x
2.0 acald_c --> actn_R_c
acald_e <=> acald_c
acald_m <=> acald_c
accoa_c + atp_c + hco3_c <=> adp_c + h_c + malcoa_c + pi_c
accoa_m + atp_m + hco3_m <=> adp_m + h_m + malcoa_m + pi_m
accoa_c <=> accoa_n
aces_c --> aces_e
accoa_c + gam6p_c <=> acgam6p_c + coa_c + h_c
acgam6p_c <=> acgam1p_c
acglu_m + atp_m --> acg5p_m + adp_m
accoa_m + glu_L_m --> acglu_m + coa_m + h_m
2obut_m + h_m + pyr_m --> 2ahbut_m + co2_m
h2o_c + iamac_c --> ac_c + h_c + iamoh_c
h2o_c + ibutac_c --> ac_c + h_c + ibutoh_c
aces_c + h2o_c --> ac_c + etoh_c + h_c
h_m + 2.0 pyr_m --> alac_S_m + co2_m
accoa_m + h2o_m --> ac_m + coa_m + h_m
dcacoa_x + o2_x --> dc2coa_x + h2o2_x
ddcacoa_x + o2_x --> dd2coa_x + h2o2_x
o2_x + tdcoa_x --> h2o2_x + td2coa_x
o2_x + pmtcoa_x --> h2o2_x + hdd2coa_x
o2_x + stcoa_x --> h2o2_x + od2coa_x
hexccoa_x + o2_x --> h2o2_x + hxc2coa_x
ACP_c + accoa_c <=> acACP_c + coa_c
ACP_m + accoa_m <=> acACP_m + coa_m
acon_T_c + amet_c --> acon5m_c + ahcys_c
cit_c <=> icit_c
2mcit_m <=> micit_m
cit_m <=> icit_m
acg5sa_m + glu_L_m --> acorn_m + akg_m
fmn_e + h2o_e --> pi_e + ribflv_e
coa_m + h2o_m --> 2.0 h_m + pan4p_m + pap_m
acrn_c --> acrn_m
acrn_x --> acrn_c
ac_c + atp_c + coa_c --> accoa_c + amp_c + ppi_c
ac_m + atp_m + coa_m --> accoa_m + amp_m + ppi_m
ac_x + atp_x + coa_x --> accoa_x + amp_x + ppi_x
ac_e + h_e <=> ac_c + h_c
ac_c <=> ac_m
ac_c <=> ac_x
ac_e <=> ac_c
adn_c + h2o_c + h_c --> ins_c + nh4_c
4adcho_c --> 4abz_c + h_c + pyr_c
chor_c + gln_L_c --> 4adcho_c + glu_L_c
ade_c + h2o_c + h_c --> hxan_c + nh4_c
ade_e + h_e --> ade_c + h_c
ade_c <=> ade_m
0.01 1agly3p_SC_c + h_c + nadph_c --> 0.01 1ag3p_SC_c + nadp_c
amp_c + atp_c <=> 2.0 adp_c
amp_m + atp_m <=> 2.0 adp_m
amp_c + gtp_c <=> adp_c + gdp_c
amp_m + gtp_m <=> adp_m + gdp_m
amp_c + itp_c <=> adp_c + idp_c
amp_m + itp_m <=> adp_m + idp_m
amet_c + h_c --> ametam_c + co2_c
atp_c --> camp_c + ppi_c
adn_c + atp_c --> adp_c + amp_c + h_c
adn_c + h2o_c --> ade_c + rib_D_c
adn_e + h_e --> adn_c + h_c
ade_c + prpp_c --> amp_c + ppi_c
aps_c + atp_c --> adp_c + h_c + paps_c
dcamp_c <=> amp_c + fum_c
25aics_c <=> aicar_c + fum_c
asp_L_c + gtp_c + imp_c --> dcamp_c + gdp_c + 2.0 h_c + pi_c
0.01 1ag3p_SC_c + 0.02 dcacoa_c + 0.06 ddcacoa_c + 0.17 hdcoa_c + 0.09 ocdycacoa_c + 0.24 odecoa_c + 0.27 pmtcoa_c + 0.05 stcoa_c + 0.1 tdcoa_c --> coa_c + 0.01 pa_SC_c
acg5p_m + h_m + nadph_m --> acg5sa_m + nadp_m + pi_m
ala_L_c + glx_c --> gly_c + pyr_c
ahcys_c <=> ahcys_m
ahcys_c + h2o_c --> adn_c + hcys_L_c
air_c + 2.0 h_c --> 4ahmmp_c + gcald_c + pi_c
achms_c + ch4s_c --> ac_c + h_c + met_L_c
achms_c + h2s_c --> ac_c + h_c + hcys_L_c
10fthf_c + aicar_c <=> fprica_c + thf_c
air_c + co2_c <=> 5aizc_c + h_c
akg_m + h_m + lpam_m <=> co2_m + sdhlam_m
coa_m + sdhlam_m --> dhlam_m + succoa_m
akg_c + mal_L_e <=> akg_e + mal_L_c
akg_c + h_c <=> akg_n + h_n
akg_e + h_e <=> akg_c + h_c
akg_c <=> akg_x
ahdt_c + 3.0 h2o_c --> dhnpt_c + 2.0 h_c + 3.0 pi_c
gly_m + h_m + succoa_m --> 5aop_m + co2_m + coa_m
akg_c + ala_L_c <=> glu_L_c + pyr_c
akg_m + ala_L_m <=> glu_L_m + pyr_m
ala_L_c + atp_c + trnaala_c --> alatrna_c + amp_c + ppi_c
ala_L_e + h_e <=> ala_L_c + h_c
ala_L_m --> ala_L_c
glyald_c + h_c + nadph_c --> glyc_c + nadp_c
2mbald_c + h_c + nadh_c --> 2mbtoh_c + nad_c
2mbald_m + h_m + nadh_m --> 2mbtoh_m + nad_m
2mbald_c + h_c + nadph_c --> 2mbtoh_c + nadp_c
2mppal_c + h_c + nadh_c --> ibutoh_c + nad_c
2mppal_m + h_m + nadh_m --> ibutoh_m + nad_m
2mppal_c + h_c + nadph_c --> ibutoh_c + nadp_c
3mbald_c + h_c + nadh_c --> iamoh_c + nad_c
3mbald_m + h_m + nadh_m --> iamoh_m + nad_m
3mbald_c + h_c + nadph_c --> iamoh_c + nadp_c
h_c + nadh_c + pacald_c --> 2phetoh_c + nad_c
h_m + nadh_m + pacald_m --> 2phetoh_m + nad_m
h_c + nadph_c + pacald_c --> 2phetoh_c + nadp_c
h_c + id3acald_c + nadh_c --> ind3eth_c + nad_c
h_m + id3acald_m + nadh_m --> ind3eth_m + nad_m
etoh_c + nad_c --> acald_c + h_c + nadh_c
acald_c + h_c + nadh_c --> etoh_c + nad_c
acald_m + h_m + nadh_m --> etoh_m + nad_m
etoh_c + nad_c <=> acald_c + h_c + nadh_c
h2o_c + nad_c + pacald_c --> 2.0 h_c + nadh_c + pac_c
h2o_m + id3acald_m + nad_m --> 2.0 h_m + ind3ac_m + nadh_m
h2o_c + id3acald_c + nadp_c --> 2.0 h_c + ind3ac_c + nadph_c
h2o_m + id3acald_m + nadp_m --> 2.0 h_m + ind3ac_m + nadph_m
aproa_c + h2o_c + nad_c --> ala_B_c + 2.0 h_c + nadh_c
acald_m + h2o_m + nad_m --> ac_m + 2.0 h_m + nadh_m
acald_c + h2o_c + nadp_c --> ac_c + 2.0 h_c + nadph_c
acald_m + h2o_m + nadp_m --> ac_m + 2.0 h_m + nadph_m
alltt_c + h2o_c <=> urdglyc_c + urea_c
alltn_c + h2o_c <=> alltt_c + h_c
alltn_e --> alltn_c
alltt_e --> alltt_c
allphn_c + h2o_c + 3.0 h_c --> 2.0 co2_c + 2.0 nh4_c
8aonn_c + amet_c <=> amob_c + dann_c
amet_e + h_e --> amet_c + h_c
amet_c <=> amet_m
4gudbd_c + h2o_c --> 4gudbutn_c + nh4_c
h2o_c + pad_c --> nh4_c + pac_c
h2o_c + iad_c --> ind3ac_c + nh4_c
amp_c + h2o_c + h_c --> imp_c + nh4_c
amp_c + h2o_c --> ade_c + r5p_c
amp_n <=> amp_c
anth_c + prpp_c --> ppi_c + pran_c
chor_c + gln_L_c --> anth_c + glu_L_c + h_c + pyr_c
2aobut_c + h_c --> aact_c + co2_c
ap4a_c + h2o_c <=> 2.0 adp_c + 2.0 h_c
aprut_c + h2o_c + o2_c --> h2o2_c + n4abutn_c + nh4_c
Dara14lac_c + o2_c <=> ertascb_D_c + h2o2_c
arab_D_c + nadp_c --> Dara14lac_c + h_c + nadph_c
arab_L_c + h_c + nadph_c --> abt_c + nadp_c
arab_D_e <=> arab_D_c
arab_L_e <=> arab_L_c
arg_L_c + h2o_c --> orn_c + urea_c
argsuc_c <=> arg_L_c + fum_c
asp_L_c + atp_c + citr_L_c <=> amp_c + argsuc_c + h_c + ppi_c
arg_L_c + atp_c + trnaarg_c --> amp_c + argtrna_c + ppi_c
arg_L_m + atp_m + trnaarg_m --> amp_m + argtrna_m + ppi_m
arg_L_c + h_c <=> arg_L_m + h_m
arg_L_e + h_e <=> arg_L_c + h_c
arg_L_c + h_v --> arg_L_v + h_c
amet_c + his_L_c --> NPmehis_c + ahcys_c + h_c
4pasp_c + h_c + nadph_c --> aspsa_c + nadp_c + pi_c
asn_L_c + h2o_c --> asp_L_c + nh4_c
asn_L_e + h2o_e --> asp_L_e + nh4_e
asp_L_c + atp_c + gln_L_c + h2o_c --> amp_c + asn_L_c + glu_L_c + h_c + ppi_c
asn_L_c + atp_c + trnaasn_c --> amp_c + asntrna_c + ppi_c
asn_L_m + atp_m + trnaasn_m --> amp_m + asntrna_m + ppi_m
asn_L_c + h_c <=> asn_L_m + h_m
asn_L_e + h_e <=> asn_L_c + h_c
asn_L_c + h_v --> asn_L_v + h_c
asn_L_v + h_v --> asn_L_c + h_c
asp_L_c + cbp_c --> cbasp_c + h_c + pi_c
asp_L_m + glu_L_c --> asp_L_c + glu_L_m
asp_L_c + glu_L_x <=> asp_L_x + glu_L_c
asp_L_c + atp_c --> 4pasp_c + adp_c
asp_L_c + fad_m --> fadh2_m + h_c + iasp_c
akg_c + asp_L_c <=> glu_L_c + oaa_c
akg_m + asp_L_m <=> glu_L_m + oaa_m
akg_x + asp_L_x <=> glu_L_x + oaa_x
asp_L_c + atp_c + trnaasp_c --> amp_c + asptrna_c + ppi_c
asp_L_m + atp_m + trnaasp_m --> amp_m + asptrna_m + ppi_m
asp_L_c + h_c <=> asp_L_m + h_m
asp_L_c + h_c <=> asp_L_n + h_n
asp_L_e + h_e <=> asp_L_c + h_c
asp_L_n <=> asp_L_c
asp_L_v + h_v --> asp_L_c + h_c
athr_L_c + nadp_c <=> 2aobut_c + h_c + nadph_c
amp_x + atp_c + h_x --> amp_c + atp_x + h_c
adp_c + atp_c + h_c --> ap4a_c + pi_c
adp_c + gtp_c + h_c --> ap4g_c + pi_c
gdp_c + gtp_c + h_c --> gp4g_c + pi_c
atp_c + 2.0 h2o_c --> amp_c + 2.0 h_c + 2.0 pi_c
atp_c + h2o_c --> adp_c + h_c + pi_c
atp_c + prpp_c --> ppi_c + prbatp_c
atp_c + h2o_c --> adp_c + h_e + pi_c
adp_g + 3.0 h_c + pi_g --> atp_g + h2o_g + 2.0 h_g
adp_m + 3.0 h_c + pi_m --> atp_m + h2o_m + 2.0 h_m
adp_v + 3.0 h_c + pi_v --> atp_v + h2o_v + 2.0 h_v
adp_c + atp_m + h_c --> adp_m + atp_c + h_m
adp_x + atp_c + h_x --> adp_c + atp_x + h_c
atp_c + btn_c + h_c --> btamp_c + ppi_c
h2o_c + pap_c --> amp_c + pi_c
btd_RR_c + nad_c <=> actn_R_c + h_c + nadh_c
btd_RR_c <=> btd_RR_e
btn_e + h_e --> btn_c + h_c
dtbt_c + s_c <=> btn_c + 2.0 h_c
44mctr_c + h_c + nadph_c --> 44mzym_c + nadp_c
ergtrol_c + h_c + nadph_c + o2_c --> ergtetrol_c + 2.0 h2o_c + nadp_c
ergtrol_c + h_c + nadh_c + o2_c --> ergtetrol_c + 2.0 h2o_c + nad_c
ergtetrol_r + h_r + nadph_r --> ergst_r + nadp_r
4mzym_int1_c + nad_c --> 4mzym_int2_c + co2_c + h_c + nadh_c
nad_c + zym_int1_c --> co2_c + h_c + nadh_c + zym_int2_c
4mzym_int2_c + h_c + nadph_c --> 4mzym_c + nadp_c
h_c + nadph_c + zym_int2_c --> nadp_c + zymst_c
44mzym_c + 3.0 h_c + 3.0 nadph_c + 3.0 o2_c --> 4mzym_int1_c + 4.0 h2o_c + 3.0 nadp_c
4mzym_c + 3.0 h_c + 3.0 nadph_c + 3.0 o2_c --> 4.0 h2o_c + 3.0 nadp_c + zym_int1_c
epist_c + h_c + nadph_c + o2_c --> ergtrol_c + 2.0 h2o_c + nadp_c
fecost_c --> epist_c
2.0 h2o2_c --> 2.0 h2o_c + o2_c
2.0 h2o2_x --> 2.0 h2o_x + o2_x
cbasp_n <=> cbasp_c
2.0 atp_c + gln_L_c + h2o_c + hco3_c --> 2.0 adp_c + cbp_c + glu_L_c + 2.0 h_c + pi_c
cbp_c <=> cbp_n
2.0 focytc_m + h2o2_m --> 2.0 ficytc_m + 2.0 h2o_m
0.01 cdpdag_SC_m + glyc3p_m <=> cmp_m + h_m + 0.01 pgp_SC_m
cdp_c <=> cdp_n
cer1_24_c <=> cer1_24_r
cer1_26_c <=> cer1_26_r
cer2_24_c <=> cer2_24_r
cer2_26_c <=> cer2_26_r
cer1_24_r + coa_r + h_r --> sphgn_r + ttccoa_r
cer1_26_r + coa_r + h_r --> hexccoa_r + sphgn_r
cer2_24_r + coa_r + h_r --> psphings_r + ttccoa_r
cer2_26_r + coa_r + h_r --> hexccoa_r + psphings_r
cer1_24_c + h_c + nadph_c + o2_c --> cer2_24_c + h2o_c + nadp_c
cer1_26_c + h_c + nadph_c + o2_c --> cer2_26_c + h2o_c + nadp_c
sphgn_c + ttccoa_c --> cer1_24_c + coa_c + h_c
sphgn_r + ttccoa_r --> cer1_24_r + coa_r + h_r
hexccoa_c + sphgn_c --> cer1_26_c + coa_c + h_c
hexccoa_r + sphgn_r --> cer1_26_r + coa_r + h_r
psphings_c + ttccoa_c --> cer2_24_c + coa_c + h_c
psphings_r + ttccoa_r --> cer2_24_r + coa_r + h_r
hexccoa_c + psphings_c --> cer2_26_c + coa_c + h_c
hexccoa_r + psphings_r --> cer2_26_r + coa_r + h_r
cer1_24_c + h_c + nadph_c + o2_c --> cer2__24_c + h2o_c + nadp_c
cer1_26_c + h_c + nadph_c + o2_c --> cer2__26_c + h2o_c + nadp_c
cer2_24_c + h_c + nadph_c + o2_c --> cer3_24_c + h2o_c + nadp_c
cer2_26_c + h_c + nadph_c + o2_c --> cer3_26_c + h2o_c + nadp_c
cholp_c + ctp_c + h_c --> cdpchol_c + ppi_c
amet_c + o2_c + zymst_c --> ahcys_c + ergtetrol_c + 2.0 h2o_c + h_c
chol_e + h_e --> chol_c + h_c
atp_c + chol_c --> adp_c + cholp_c + h_c
chor_c --> pphn_c
3psme_c --> chor_c + pi_c
chor_c --> 4hbz_c + pyr_c
chitin_c + h2o_c --> ac_c + chitos_c + h_c
udpacgal_c --> chitin_c + h_c + udp_c
cit_e + h_e <=> cit_c + h_c
cit_c + mal_L_m <=> cit_m + mal_L_c
cit_x + mal_L_c <=> cit_c + mal_L_x
cit_c + pep_m <=> cit_m + pep_c
cit_c + icit_m <=> cit_m + icit_c
cit_c + icit_x <=> cit_x + icit_c
0.01 cdpdag_SC_m + 0.01 pg_SC_m --> 0.01 clpn_SC_m + cmp_m + h_m
cmp_c + h2o_c --> csn_c + r5p_c
co2_e <=> co2_c
co2_c <=> co2_g
co2_c <=> co2_m
co2_n <=> co2_c
co2_c <=> co2_x
co2_c <=> co2_v
coa_x + h2o_x --> 2.0 h_x + pan4p_x + pap_x
coa_c --> coa_m
coa_c <=> coa_n
T4hcinnm_m + atp_m + coa_m --> amp_m + coucoa_m + ppi_m
cpppg3_c + 2.0 h_c + o2_c --> 2.0 co2_c + 2.0 h2o_c + pppg9_c
acrn_c + crn_m --> acrn_m + crn_c
acrn_x + crn_c --> acrn_c + crn_x
crn_e <=> crn_c
crn_m --> crn_c
crn_c --> crn_x
acrn_m + coa_m <=> accoa_m + crn_m
accoa_x + crn_x <=> acrn_x + coa_x
accoa_c + crn_c <=> acrn_c + coa_c
csn_c + h2o_c + h_c --> nh4_c + ura_c
csn_e + h_e --> csn_c + h_c
accoa_m + h2o_m + oaa_m --> cit_m + coa_m + h_m
accoa_x + h2o_x + oaa_x --> cit_x + coa_x + h_x
atp_c + nh4_c + utp_c --> adp_c + ctp_c + 2.0 h_c + pi_c
atp_c + gln_L_c + h2o_c + utp_c --> adp_c + ctp_c + glu_L_c + 2.0 h_c + pi_c
cmp_m + ctp_c + 2.0 h_c --> cmp_c + ctp_m + 2.0 h_m
4.0 focytc_m + 6.0 h_m + o2_m --> 4.0 ficytc_m + 2.0 h2o_m + 6.0 h_c
2.0 ficytc_m + 1.5 h_m + q6h2_m --> 2.0 focytc_m + 1.5 h_c + q6_m
acser_c + h2s_c --> ac_c + cys_L_c + h_c
cyst_L_c + h2o_c --> 2obut_c + cys_L_c + nh4_c
cyst_L_c + h2o_c --> hcys_L_c + nh4_c + pyr_c
cyst_L_x + h2o_x --> hcys_L_x + nh4_x + pyr_x
atp_c + cys_L_c + trnacys_c --> amp_c + cystrna_c + ppi_c
hcys_L_c + ser_L_c --> cyst_L_c + h2o_c
cyst_L_c <=> cyst_L_x
cys_L_e + h_e <=> cys_L_c + h_c
cytd_c + h2o_c + h_c --> nh4_c + uri_c
cytd_c + gtp_c --> cmp_c + gdp_c + h_c
cytd_e + h_e --> cytd_c + h_c
atp_c + cmp_c <=> adp_c + cdp_c
atp_c + dcmp_c <=> adp_c + dcdp_c
dad_2_c + h2o_c + h_c --> din_c + nh4_c
atp_c + damp_c <=> adp_c + dadp_c
dad_2_e + h_e --> dad_2_c + h_c
dadp_c <=> dadp_n
0.01 12dgr_SC_c + cdpchol_c --> cmp_c + h_c + 0.01 pc_SC_c
h2o_c + 0.01 pa_SC_c --> 0.01 12dgr_SC_c + pi_c
dann_e + h_e <=> dann_c + h_c
ctp_c + h_c + 0.01 pa_SC_c <=> 0.01 cdpdag_SC_c + ppi_c
ctp_m + h_m + 0.01 pa_SC_m <=> 0.01 cdpdag_SC_m + ppi_m
ru5p_D_c --> db4p_c + for_c + h_c
atp_c + co2_c + dann_c <=> adp_c + dtbt_c + 3.0 h_c + pi_c
dcdp_c <=> dcdp_n
dcmp_c + h2o_c + h_c <=> dump_c + nh4_c
dctp_c + h2o_c + h_c --> dutp_c + nh4_c
dcyt_c + h2o_c + h_c --> duri_c + nh4_c
dcyt_e + h_e --> dcyt_c + h_c
e4p_c + h2o_c + pep_c --> 2dda7p_c + pi_c
e4p_m + h2o_m + pep_m --> 2dda7p_m + pi_m
h_c + nadph_c + o2_c + tdcoa_c --> 2.0 h2o_c + nadp_c + tdecoa_c
h_c + nadph_c + o2_c + pmtcoa_c --> 2.0 h2o_c + hdcoa_c + nadp_c
h_c + nadph_c + o2_c + stcoa_c --> 2.0 h2o_c + nadp_c + odecoa_c
h_c + nadph_c + o2_c + odecoa_c --> 2.0 h2o_c + nadp_c + ocdycacoa_c
dgdp_c <=> dgdp_n
6dg_c + h2o_c --> gal_c + glc_D_c
atp_c + dgmp_c <=> adp_c + dgdp_c
dgsn_e + h_e --> dgsn_c + h_c
23dhmb_m --> 3mob_m + h2o_m
23dhmp_m --> 3mop_m + h2o_m
atp_c + dha_c --> adp_c + dhap_c + h_c
dhap_m --> dhap_c
dhf_c + h_c + nadph_c --> nadp_c + thf_c
dhf_m + h_m + nadph_m --> nadp_m + thf_m
atp_c + dhpt_c + glu_L_c --> adp_c + dhf_c + h_c + pi_c
dhf_c <=> dhf_m
dhnpt_m --> 2ahhmp_m + gcald_m + h_m
dhnpt_c <=> dhnpt_m
dhor_S_c + q6_m --> orot_c + q6h2_m
dhor_S_c + fum_c --> orot_c + succ_c
dhor_S_c + o2_c --> h2o2_c + orot_c
dhor_S_c + h2o_c <=> cbasp_c + h_c
2ahhmp_m + 4abz_m --> dhpt_m + h2o_m
dhpt_c <=> dhpt_m
2dda7p_c --> 3dhq_c + pi_c
3dhq_c --> 3dhsk_c + h2o_c
accoa_c + sprm_c --> N1sprm_c + coa_c + h_c
din_e + h_e --> din_c + h_c
amet_c + caphis_c --> ahcys_c + cmaphis_c + h_c
dkmpp_c + 3.0 h2o_c --> 2kmb_c + for_c + 6.0 h_c + pi_c
dmpp_c + ipdp_c --> grdp_c + ppi_c
dhpmp_c + h2o_c --> dhnpt_c + pi_c
ahdt_c + h2o_c --> dhpmp_c + h_c + ppi_c
ctp_c + dolichol_c --> cdp_c + dolp_c + h_c
dolmanp_r --> dolp_r + h_r + mannan_r
dolp_c + gdpmann_c --> dolmanp_r + gdp_c
dolp_c + h_c <=> dolp_r + h_r
atp_c + dpcoa_c --> adp_c + coa_c + h_c
atp_m + dpcoa_m --> adp_m + coa_m + h_m
13dpg_c <=> 23dpg_c + h_c
5dpmev_c + atp_c --> adp_c + co2_c + ipdp_c + pi_c
2dhp_c + h_c + nadph_c --> nadp_c + pant_R_c
2dhp_m + h_m + nadph_m --> nadp_m + pant_R_m
atp_c + drib_c --> 2dr5p_c + adp_c + h_c
25dhpp_c + h_c + nadph_c --> 25dthpp_c + nadp_c
25dthpp_c + h2o_c + h_c --> 5aprbu_c + nh4_c
atp_c + dtmp_c <=> adp_c + dtdp_c
dttp_e <=> dttp_c
dump_c <=> dump_n
atp_c + duri_c --> adp_c + dump_c + h_c
duri_c + pi_c <=> 2dr1p_c + ura_c
duri_e + h_e --> duri_c + h_c
dutp_c + h2o_c --> dump_c + h_c + ppi_c
h2o_c + q6_m + spmd_c --> 13dampp_c + 4abutn_c + q6h2_m
2.0 ficytc_m + lac_D_c --> 2.0 focytc_m + pyr_c
2.0 ficytc_m + lac_D_m --> 2.0 focytc_m + pyr_m
h_e + lac_D_e <=> h_c + lac_D_c
lac_D_c + pyr_m <=> lac_D_m + pyr_c
h_c + lac_D_c <=> h_m + lac_D_m
e4hglu_c <=> e4hglu_m
e4hglu_c <=> e4hglu_x
e4p_c <=> e4p_m
h2o_x + hxc2coa_x <=> 3hxccoa_x
3hdcoa_x <=> dc2coa_x + h2o_x
3hddcoa_x <=> dd2coa_x + h2o_x
3htdcoa_x <=> h2o_x + td2coa_x
3hhdcoa_x <=> h2o_x + hdd2coa_x
3hodcoa_x <=> h2o_x + od2coa_x
akg_c + e4hglu_c --> 4h2oglt_c + glu_L_c
akg_m + e4hglu_m --> 4h2oglt_m + glu_L_m
akg_x + e4hglu_x --> 4h2oglt_x + glu_L_x
2pg_c <=> h2o_c + pep_c
h2o_e + pectin_e --> galur_e
0.01 epist_c + 0.655 hdcoa_c + 0.01 hexccoa_c + 0.27 odecoa_c + 0.02 pmtcoa_c + 0.03 stcoa_c + 0.015 tdcoa_c --> coa_c + 0.01 epistest_SC_c
0.01 epistest_SC_c + h2o_c --> 0.01 epist_c + h_c + 0.02 hdca_c + 0.655 hdcea_c + 0.01 hexc_c + 0.03 ocdca_c + 0.27 ocdcea_c + 0.015 ttdca_c
0.01 epistest_SC_e + h2o_e --> 0.01 epist_e + h_e + 0.02 hdca_e + 0.655 hdcea_e + 0.01 hexc_e + 0.03 ocdca_e + 0.27 ocdcea_e + 0.015 ttdca_e
epist_e <=> epist_c
epm_c + h2o_c <=> gal_c + man_c
0.01 ergst_c + 0.655 hdcoa_c + 0.01 hexccoa_c + 0.27 odecoa_c + 0.02 pmtcoa_c + 0.03 stcoa_c + 0.015 tdcoa_c --> coa_c + 0.01 ergstest_SC_c
0.01 ergstest_SC_c + h2o_c --> 0.01 ergst_c + h_c + 0.02 hdca_c + 0.655 hdcea_c + 0.01 hexc_c + 0.03 ocdca_c + 0.27 ocdcea_c + 0.015 ttdca_c
0.01 ergstest_SC_e + h2o_e --> 0.01 ergst_e + h_e + 0.02 hdca_e + 0.655 hdcea_e + 0.01 hexc_e + 0.03 ocdca_e + 0.27 ocdcea_e + 0.015 ttdca_e
ergst_c + udpg_c --> ergst3glc_c + h_c + udp_c
ergst_e <=> ergst_c
ergst_r <=> ergst_c
ergtetrol_c <=> ergtetrol_r
atp_c + etha_c --> adp_c + ethamp_c + h_c
0.01 12dgr_SC_c + cdpea_c <=> cmp_c + h_c + 0.01 pe_SC_c
etha_e <=> etha_c
etoh_e <=> etoh_c
etoh_c <=> etoh_m
13BDglcn_e -->
2hb_e -->
2mbac_e -->
2mbald_e -->
2mbtoh_e -->
2mppal_e -->
2phetoh_e -->
3c3hmp_e -->
3mbald_e -->
3mop_e -->
4abut_e -->
4abz_e -->
5aop_e -->
8aonn_e -->
Nbfortyr_e -->
abt_e -->
ac_e -->
acald_e -->
aces_e -->
ade_e -->
adn_e -->
akg_e -->
ala_L_e -->
alltn_e -->
alltt_e -->
amet_e -->
arab_D_e -->
arab_L_e -->
arg_L_e -->
asn_L_e -->
asp_L_e -->
btd_RR_e -->
btn_e -->
chol_e -->
cit_e -->
co2_e -->
crn_e -->
csn_e -->
cys_L_e -->
cytd_e -->
dad_2_e -->
dann_e -->
dca_e -->
dcyt_e -->
ddca_e -->
dgsn_e -->
din_e -->
dttp_e -->
duri_e -->
epist_e -->
epistest_SC_e -->
ergst_e -->
ergstest_SC_e -->
etha_e -->
etoh_e -->
fe2_e <=>
fecost_e -->
fecostest_SC_e -->
fmn_e -->
for_e -->
fru_e -->
fum_e -->
g3pc_e -->
g3pi_e -->
gal_e -->
galur_e -->
gam6p_e -->
gcald_e -->
glc_D_e <=>
gln_L_e -->
glu_L_e -->
glx_e -->
gly_e -->
glyc_e -->
gsn_e -->
gthox_e -->
gthrd_e -->
gua_e -->
h2o_e <=>
h_e <=>
hdca_e -->
hdcea_e -->
hexc_e -->
his_L_e -->
hxan_e -->
iamac_e -->
iamoh_e -->
ibutac_e -->
ibutoh_e -->
id3acald_e -->
ile_L_e -->
ind3eth_e -->
inost_e -->
ins_e -->
k_e <=>
lac_D_e -->
lac_L_e -->
lanost_e -->
lanostest_SC_e -->
leu_L_e -->
lys_L_e -->
mal_L_e -->
malt_e -->
man_e -->
melib_e -->
met_L_e -->
mmet_e -->
na1_e <=>
nac_e -->
nadp_e -->
nh4_e <=>
nmn_e -->
o2_e <=>
oaa_e -->
ocdca_e -->
ocdcea_e -->
ocdcya_e -->
orn_e -->
pacald_e -->
pap_e -->
pc_SC_e -->
pectin_e -->
pepd_e -->
phe_L_e -->
pheac_e -->
pi_e <=>
pnto_R_e -->
pro_L_e -->
ptd1ino_SC_e -->
ptrc_e -->
pyr_e -->
rib_D_e -->
ribflv_e -->
sbt_D_e -->
sbt_L_e -->
ser_L_e -->
so3_e -->
so4_e <=>
spmd_e -->
sprm_e -->
srb_L_e -->
succ_e -->
sucr_e -->
taur_e -->
thm_e -->
thmmp_e -->
thmpp_e -->
thr_L_e -->
thym_e -->
thymd_e -->
tre_e -->
trp_L_e -->
ttdca_e -->
tyr_L_e -->
ura_e -->
urea_e -->
uri_e -->
val_L_e -->
xan_e -->
xtsn_e -->
xyl_D_e -->
xylt_e -->
zymst_e -->
zymstest_SC_e -->
dca_c --> dca_x
ddcaACP_c + h2o_c <=> ACP_c + ddca_c + h_c
ddcaACP_m --> ddcaACP_c
ddca_c --> ddca_x
h2o_c + myrsACP_c <=> ACP_c + h_c + ttdca_c
myrsACP_m --> myrsACP_c
atp_x + h2o_x + tdcoa_c --> adp_x + h_x + pi_x + tdcoa_x
ttdca_c --> ttdca_x
h2o_c + tdeACP_c <=> ACP_c + h_c + ttdcea_c
tdeACP_m --> tdeACP_c
atp_x + h2o_x + tdecoa_c --> adp_x + h_x + pi_x + tdecoa_x
ttdcea_c --> ttdcea_x
h2o_c + palmACP_c <=> ACP_c + h_c + hdca_c
palmACP_m --> palmACP_c
atp_x + h2o_x + pmtcoa_c --> adp_x + h_x + pi_x + pmtcoa_x
hdca_c --> hdca_x
h2o_c + hdeACP_c <=> ACP_c + h_c + hdcea_c
hdeACP_m --> hdeACP_c
atp_x + h2o_x + hdcoa_c --> adp_x + h_x + hdcoa_x + pi_x
hdcea_c --> hdcea_x
h2o_c + ocdcaACP_c <=> ACP_c + h_c + ocdca_c
ocdcaACP_m --> ocdcaACP_c
atp_x + h2o_x + stcoa_c --> adp_x + h_x + pi_x + stcoa_x
h2o_c + octeACP_c <=> ACP_c + h_c + ocdcea_c
octeACP_m --> octeACP_c
atp_x + h2o_x + odecoa_c --> adp_x + h_x + odecoa_x + pi_x
h2o_c + ocdcyaACP_c <=> ACP_c + h_c + ocdcya_c
ocdcyaACP_m --> ocdcyaACP_c
atp_x + h2o_x + ocdycacoa_c --> adp_x + h_x + ocdycacoa_x + pi_x
ttc_c --> ttc_x
hexc_c --> hexc_x
octa_c --> octa_x
atp_x + coa_x + dca_x <=> amp_x + dcacoa_x + ppi_x
atp_x + coa_x + ddca_x <=> amp_x + ddcacoa_x + ppi_x
atp_c + coa_c + ttdca_c <=> amp_c + ppi_c + tdcoa_c
atp_x + coa_x + ttdca_x <=> amp_x + ppi_x + tdcoa_x
atp_c + coa_c + ttdcea_c <=> amp_c + ppi_c + tdecoa_c
atp_x + coa_x + ttdcea_x <=> amp_x + ppi_x + tdecoa_x
atp_c + coa_c + hdca_c <=> amp_c + pmtcoa_c + ppi_c
atp_x + coa_x + hdca_x <=> amp_x + pmtcoa_x + ppi_x
atp_c + coa_c + hdcea_c <=> amp_c + hdcoa_c + ppi_c
atp_x + coa_x + hdcea_x <=> amp_x + hdcoa_x + ppi_x
atp_c + coa_c + ocdca_c <=> amp_c + ppi_c + stcoa_c
atp_c + coa_c + ocdcea_c <=> amp_c + odecoa_c + ppi_c
atp_c + coa_c + ocdcya_c <=> amp_c + ocdycacoa_c + ppi_c
atp_x + coa_x + ttc_x <=> amp_x + ppi_x + ttccoa_x
atp_x + coa_x + hexc_x <=> amp_x + hexccoa_x + ppi_x
atp_x + coa_x + octa_x <=> amp_x + occoa_x + ppi_x
fad_c + fmn_m --> fad_m + fmn_c
fald_c + gthrd_c + nad_c <=> Sfglutth_c + h_c + nadh_c
6.0 coa_x + 6.0 h2o_x + 6.0 nad_x + nadph_x + 6.0 o2_x + tdecoa_x --> 7.0 accoa_x + 6.0 h2o2_x + 5.0 h_x + 6.0 nadh_x + nadp_x
6.0 coa_x + 6.0 h2o_x + 6.0 nad_x + 5.0 o2_x + tdecoa_x --> 7.0 accoa_x + 5.0 h2o2_x + 6.0 h_x + 6.0 nadh_x
7.0 coa_x + 7.0 h2o_x + hdcoa_x + 7.0 nad_x + nadph_x + 7.0 o2_x --> 8.0 accoa_x + 7.0 h2o2_x + 6.0 h_x + 7.0 nadh_x + nadp_x
7.0 coa_x + 7.0 h2o_x + hdcoa_x + 7.0 nad_x + 6.0 o2_x --> 8.0 accoa_x + 6.0 h2o2_x + 7.0 h_x + 7.0 nadh_x
8.0 coa_x + 8.0 h2o_x + 8.0 nad_x + nadph_x + 8.0 o2_x + odecoa_x --> 9.0 accoa_x + 8.0 h2o2_x + 7.0 h_x + 8.0 nadh_x + nadp_x
8.0 coa_x + 8.0 h2o_x + 8.0 nad_x + 7.0 o2_x + odecoa_x --> 9.0 accoa_x + 7.0 h2o2_x + 8.0 h_x + 8.0 nadh_x
8.0 coa_x + 8.0 h2o_x + 8.0 nad_x + 2.0 nadph_x + 8.0 o2_x + ocdycacoa_x --> 9.0 accoa_x + 8.0 h2o2_x + 6.0 h_x + 8.0 nadh_x + 2.0 nadp_x
8.0 coa_x + 8.0 h2o_x + 8.0 nad_x + nadph_x + 7.0 o2_x + ocdycacoa_x --> 9.0 accoa_x + 7.0 h2o2_x + 7.0 h_x + 8.0 nadh_x + nadp_x
8.0 coa_x + 8.0 h2o_x + 8.0 nad_x + 6.0 o2_x + ocdycacoa_x --> 9.0 accoa_x + 6.0 h2o2_x + 8.0 h_x + 8.0 nadh_x
3.0 coa_x + 3.0 h2o_x + 3.0 nad_x + 3.0 o2_x + ttccoa_x --> 3.0 accoa_x + 3.0 h2o2_x + 3.0 h_x + 3.0 nadh_x + stcoa_x
3.0 coa_x + 3.0 h2o_x + 3.0 nad_x + 3.0 o2_x + occoa_x --> 4.0 accoa_x + 3.0 h2o2_x + 3.0 h_x + 3.0 nadh_x
3.0 h_c + malcoa_c + 2.0 nadph_c + octa_c --> co2_c + coa_c + dca_c + h2o_c + 2.0 nadp_c
3.0 h_m + malACP_m + 2.0 nadph_m + ocACP_m --> ACP_m + co2_m + dcaACP_m + h2o_m + 2.0 nadp_m
3.0 h_c + malcoa_c + 2.0 nadph_c + occoa_c --> co2_c + coa_c + dcacoa_c + h2o_c + 2.0 nadp_c
dca_c + 3.0 h_c + malcoa_c + 2.0 nadph_c --> co2_c + coa_c + ddca_c + h2o_c + 2.0 nadp_c
dcaACP_m + 3.0 h_m + malACP_m + 2.0 nadph_m --> ACP_m + co2_m + ddcaACP_m + h2o_m + 2.0 nadp_m
dcacoa_c + 3.0 h_c + malcoa_c + 2.0 nadph_c --> co2_c + coa_c + ddcacoa_c + h2o_c + 2.0 nadp_c
ddca_c + 3.0 h_c + malcoa_c + 2.0 nadph_c --> co2_c + coa_c + h2o_c + 2.0 nadp_c + ttdca_c
ddcaACP_m + 3.0 h_m + malACP_m + 2.0 nadph_m --> ACP_m + co2_m + h2o_m + myrsACP_m + 2.0 nadp_m
ddcacoa_c + 3.0 h_c + malcoa_c + 2.0 nadph_c --> co2_c + coa_c + h2o_c + 2.0 nadp_c + tdcoa_c
ddca_c + 4.0 h_c + malcoa_c + 3.0 nadph_c + o2_c --> co2_c + coa_c + 3.0 h2o_c + 3.0 nadp_c + ttdcea_c
ddcaACP_m + 4.0 h_m + malACP_m + 3.0 nadph_m + o2_m --> ACP_m + co2_m + 3.0 h2o_m + 3.0 nadp_m + tdeACP_m
3.0 h_c + malcoa_c + 2.0 nadph_c + ttdca_c --> co2_c + coa_c + h2o_c + hdca_c + 2.0 nadp_c
3.0 h_m + malACP_m + myrsACP_m + 2.0 nadph_m --> ACP_m + co2_m + h2o_m + 2.0 nadp_m + palmACP_m
3.0 h_c + malcoa_c + 2.0 nadph_c + tdcoa_c --> co2_c + coa_c + h2o_c + 2.0 nadp_c + pmtcoa_c
4.0 h_c + malcoa_c + 3.0 nadph_c + o2_c + ttdca_c --> co2_c + coa_c + 3.0 h2o_c + hdcea_c + 3.0 nadp_c
4.0 h_m + malACP_m + myrsACP_m + 3.0 nadph_m + o2_m --> ACP_m + co2_m + 3.0 h2o_m + hdeACP_m + 3.0 nadp_m
3.0 h_c + hdca_c + malcoa_c + 2.0 nadph_c --> co2_c + coa_c + h2o_c + 2.0 nadp_c + ocdca_c
3.0 h_m + malACP_m + 2.0 nadph_m + palmACP_m --> ACP_m + co2_m + h2o_m + 2.0 nadp_m + ocdcaACP_m
3.0 h_c + malcoa_c + 2.0 nadph_c + pmtcoa_c --> co2_c + coa_c + h2o_c + 2.0 nadp_c + stcoa_c
4.0 h_c + hdca_c + malcoa_c + 3.0 nadph_c + o2_c --> co2_c + coa_c + 3.0 h2o_c + 3.0 nadp_c + ocdcea_c
4.0 h_m + malACP_m + 3.0 nadph_m + o2_m + palmACP_m --> ACP_m + co2_m + 3.0 h2o_m + 3.0 nadp_m + octeACP_m
5.0 h_m + malACP_m + 4.0 nadph_m + 2.0 o2_m + palmACP_m --> ACP_m + co2_m + 5.0 h2o_m + 4.0 nadp_m + ocdcyaACP_m
9.0 h_c + 3.0 malcoa_c + 6.0 nadph_c + ocdca_c --> 3.0 co2_c + 3.0 coa_c + 3.0 h2o_c + 6.0 nadp_c + ttc_c
3.0 h_c + malcoa_c + 2.0 nadph_c + ttc_c --> co2_c + coa_c + h2o_c + hexc_c + 2.0 nadp_c
acACP_m + 9.0 h_m + 3.0 malACP_m + 6.0 nadph_m --> 3.0 ACP_m + 3.0 co2_m + 3.0 h2o_m + 6.0 nadp_m + ocACP_m
accoa_c + 9.0 h_c + 3.0 malcoa_c + 6.0 nadph_c --> 3.0 co2_c + 3.0 coa_c + 3.0 h2o_c + 6.0 nadp_c + occoa_c
accoa_c + 8.0 h_c + 3.0 malcoa_c + 6.0 nadph_c --> 3.0 co2_c + 4.0 coa_c + 2.0 h2o_c + 6.0 nadp_c + octa_c
fdp_c <=> dhap_c + g3p_c
f1p_c <=> dhap_c + glyald_c
s17bp_c <=> dhap_c + e4p_c
fdp_c + h2o_c --> f6p_c + pi_c
f26bp_c + h2o_c --> f6p_c + pi_c
fe2_m + ppp9_m --> 2.0 h_m + pheme_m
for_c + nad_c --> co2_c + nadh_c
for_c + h_c + q6_m --> co2_c + q6h2_m
fe2_e --> fe2_c
fe2_c --> fe2_m
0.01 fecost_c + 0.655 hdcoa_c + 0.01 hexccoa_c + 0.27 odecoa_c + 0.02 pmtcoa_c + 0.03 stcoa_c + 0.015 tdcoa_c --> coa_c + 0.01 fecostest_SC_c
0.01 fecostest_SC_c + h2o_c --> 0.01 fecost_c + h_c + 0.02 hdca_c + 0.655 hdcea_c + 0.01 hexc_c + 0.03 ocdca_c + 0.27 ocdcea_c + 0.015 ttdca_c
0.01 fecostest_SC_e + h2o_e --> 0.01 fecost_e + h_e + 0.02 hdca_e + 0.655 hdcea_e + 0.01 hexc_e + 0.03 ocdca_e + 0.27 ocdcea_e + 0.015 ttdca_e
fecost_e <=> fecost_c
fe2_m --> fe2_c
Lfmkynr_c + h2o_c --> Lkynr_c + for_c + h_c
10fthf_m + mettrna_m --> fmettrna_m + h_m + thf_m
atp_c + fmn_c + h_c --> fad_c + ppi_c
atp_m + fmn_m + h_m --> fad_m + ppi_m
fmn_c + h_c + nadh_c --> fmnh2_c + nad_c
fmn_c + h_c + nadph_c --> fmnh2_c + nadp_c
2ahhmd_m + 4abz_m --> dhpt_m + ppi_m
for_e <=> for_c
for_m --> for_c
frdp_c <=> frdp_m
fadh2_m + fum_c --> fad_m + succ_c
fadh2_m + fum_m --> fad_m + succ_m
frdp_c + ipdp_c --> ggdp_c + ppi_c
atp_c + f1p_c --> adp_c + fdp_c + h_c
fru_e + h_e --> fru_c + h_c
5fthf_c + atp_c --> adp_c + methf_c + pi_c
5fthf_m + atp_m --> adp_m + methf_m + pi_m
5fthf_c + atp_c + h2o_c --> 10fthf_c + adp_c + h_c + pi_c
atp_c + for_c + thf_c --> 10fthf_c + adp_c + pi_c
atp_m + for_m + thf_m --> 10fthf_m + adp_m + pi_m
fum_c + h2o_c <=> mal_L_c
4fumacac_c + h2o_c --> acac_c + fum_c + h_c
fum_m + h2o_m <=> mal_L_m
fum_e + h_e <=> fum_c + h_c
gdpmann_g + m2macchitppdol_g --> gdp_g + h_g + m3macchitppdol_g
gdpmann_g + m3macchitppdol_g --> gdp_g + h_g + m4macchitppdol_g
gdpmann_g + macchitppdol_g --> gdp_g + h_g + m1macchitppdol_g
gdpmann_g + m1macchitppdol_g --> gdp_g + h_g + m2macchitppdol_g
g3pc_e <=> g3pc_c
dhap_c + h_c + nadh_c --> glyc3p_c + nad_c
dhap_m + h_m + nadh_m --> glyc3p_m + nad_m
fad_m + glyc3p_m --> dhap_m + fadh2_m
g3pi_e <=> g3pi_c
glyc3p_c + h2o_c --> glyc_c + pi_c
glu5sa_c <=> 1pyr5c_c + h2o_c + h_c
glu5sa_m <=> 1pyr5c_m + h2o_m + h_m
glu5p_c + h_c + nadph_c --> glu5sa_c + nadp_c + pi_c
glu5p_c + h_c + nadh_c --> glu5sa_c + nad_c + pi_c
gam6p_c + h2o_c --> f6p_c + nh4_c
g6p_c + nadp_c --> 6pgl_c + h_c + nadph_c
g6p_r + nadp_r --> 6pgl_r + h_r + nadph_r
g6p_c <=> g6p_B_c
g6p_B_c <=> f6p_c
g6p_c <=> g6p_r
1Dgali_c + h2o_c <=> gal_c + inost_c
atp_c + gal_c --> adp_c + gal1p_c + h_c
h2o_c + melib_c --> gal_c + glc_D_c
gal1p_c + h_c + utp_c <=> ppi_c + udpgal_c
g1p_c + h_c + utp_c <=> ppi_c + udpg_c
gal_e + h_e --> gal_c + h_c
gam6p_e <=> gam6p_c
g3p_c + nad_c + pi_c <=> 13dpg_c + h_c + nadh_c
10fthf_c + gar_c --> fgam_c + h_c + thf_c
0.02 dcacoa_c + 0.06 ddcacoa_c + glyc3p_c + 0.17 hdcoa_c + 0.09 ocdycacoa_c + 0.24 odecoa_c + 0.27 pmtcoa_c + 0.05 stcoa_c + 0.1 tdcoa_c --> 0.01 1ag3p_SC_c + coa_c
0.02 dcacoa_c + 0.06 ddcacoa_c + dhap_c + 0.17 hdcoa_c + 0.09 ocdycacoa_c + 0.24 odecoa_c + 0.27 pmtcoa_c + 0.05 stcoa_c + 0.1 tdcoa_c --> 0.01 1agly3p_SC_c + coa_c
14glun_c --> glycogen_c + h2o_c
gcald_e <=> gcald_c
gcald_c <=> gcald_m
gly_m + h_m + lpam_m <=> alpam_m + co2_m
alpam_m + thf_m --> dhlam_m + mlthf_m + nh4_m
dhlam_m + nad_m <=> h_m + lpam_m + nadh_m
gly_m + h_m + lpro_m <=> alpro_m + co2_m
alpro_m + thf_m --> dhlpro_m + mlthf_m + nh4_m
dhlpro_m + nad_m <=> h_m + lpro_m + nadh_m
gdpmann_c + gmp_g --> gdpmann_g + gmp_c
gdp_g + h_c <=> gdp_c + h_g
gdp_c <=> gdp_n
f6p_c + gln_L_c --> gam6p_c + glu_L_c
ggl_c + h2o_c <=> gal_c + glyc_c
ggdp_c + ipdp_c --> pendp_c + ppi_c
ser_L_c + thf_c <=> gly_c + h2o_c + mlthf_c
ser_L_m + thf_m <=> gly_m + h2o_m + mlthf_m
atp_c + gmp_c <=> adp_c + gdp_c
datp_c + gmp_c <=> dadp_c + gdp_c
glycogen_c + h2o_c --> glc_D_c
glycogen_v + h2o_v --> glc_D_v
glycogen_c --> glycogen_v
glycogen_c + pi_c --> g1p_c
udpg_c --> glycogen_c + h_c + udp_c
glc_D_e --> glc_D_c
glc_D_c <=> glc_D_v
atp_c + glu_L_c + nh4_c --> adp_c + gln_L_c + h_c + pi_c
atp_c + gln_L_c + trnagln_c --> amp_c + glntrna_c + ppi_c
gln_L_c + h_c <=> gln_L_n + h_n
gln_L_e + h_e <=> gln_L_c + h_c
gln_L_c + h_v --> gln_L_v + h_c
gln_L_v + h_v --> gln_L_c + h_c
glp_c + tdcoa_c --> coa_c + tglp_c
atp_c + glu_L_c --> adp_c + glu5p_c
atp_c + cys_L_c + glu_L_c --> adp_c + glucys_c + h_c + pi_c
glu_L_c + h_c --> 4abut_c + co2_c
glu_L_c + h2o_c + nad_c --> akg_c + h_c + nadh_c + nh4_c
akg_c + h_c + nadph_c + nh4_c --> glu_L_c + h2o_c + nadp_c
atp_c + glc_D_c --> adp_c + g6p_B_c + h_c
gln_L_c + h2o_c --> glu_L_c + nh4_c
gln_L_c + h2o_c + prpp_c --> glu_L_c + ppi_c + pram_c
akg_c + gln_L_c + h_c + nadh_c --> 2.0 glu_L_c + nad_c
atp_c + glu_L_c + trnaglu_c --> amp_c + glutrna_c + ppi_c
atp_m + glu_L_m + trnaglu_m --> amp_m + glutrna_m + ppi_m
glu_L_c + h_c <=> glu_L_n + h_n
glu_L_e + h_e <=> glu_L_c + h_c
glu_L_c + oh1_m --> glu_L_m + oh1_c
glu_L_v + h_v --> glu_L_c + h_c
glu_L_c --> glu_L_m
glx_c <=> glx_e
glx_c <=> glx_x
2aobut_c + coa_c --> accoa_c + gly_c
glyc3p_c --> glyc3p_m
glyc_c + nadp_c --> dha_c + h_c + nadph_c
gly_m + nad_m + thf_m --> co2_m + mlthf_m + nadh_m + nh4_m
glyc_c <=> glyc_e
glyc_e + h_e --> glyc_c + h_c
h2o_c + udpg_c --> 14glun_c + h_c + udp_c
atp_c + glyc_c --> adp_c + glyc3p_c + h_c
h2o_c + lgt_S_c --> gthrd_c + h_c + lac_D_c
h2o_m + lgt_S_m --> gthrd_m + h_m + lac_D_m
atp_c + gly_c + trnagly_c --> amp_c + glytrna_c + ppi_c
gly_c + h_c <=> gly_m + h_m
gly_e + h_e <=> gly_c + h_c
atp_c + gln_L_c + h2o_c + xmp_c --> amp_c + glu_L_c + gmp_c + 2.0 h_c + ppi_c
6pgc_c + nadp_c --> co2_c + nadph_c + ru5p_D_c
gsn_c + h2o_c --> gua_c + rib_D_c
g3pc_c + h2o_c --> chol_c + glyc3p_c + h_c
grdp_c + ipdp_c --> frdp_c + ppi_c
atp_c + gsn_c --> adp_c + gmp_c + h_c
gsn_e + h_e --> gsn_c + h_c
gsn_c + h_c <=> gsn_m + h_m
gthox_c + h_c + nadph_c --> 2.0 gthrd_c + nadp_c
gthox_e --> gthox_c
gthox_m + h_m + nadph_m --> 2.0 gthrd_m + nadp_m
2.0 gthrd_c + h2o2_c <=> gthox_c + 2.0 h2o_c
2.0 gthrd_m + h2o2_m <=> gthox_m + 2.0 h2o_m
atp_v + gthrd_c + h2o_v --> adp_v + gthrd_v + h_v + pi_v
gthrd_e --> gthrd_c
atp_c + glucys_c + gly_c --> adp_c + gthrd_c + h_c + pi_c
ala_L_c + gthrd_c --> cgly_c + gluala_c
gtp_c + h2o_c --> ahdt_c + for_c + h_c
gtp_c + 3.0 h2o_c --> 25dhpp_c + for_c + 2.0 h_c + ppi_c
gtp_c + 2.0 h2o_c --> gmp_c + 2.0 h_c + 2.0 pi_c
gdp_m + gtp_c + h_c --> gdp_c + gtp_m + h_m
gua_c + h2o_c + h_c --> nh4_c + xan_c
gua_c + prpp_c --> gmp_c + ppi_c
gua_e + h_e <=> gua_c + h_c
gua_c <=> gua_m
h2o2_c <=> h2o2_n
h2o_e <=> h2o_c
h2o_c <=> h2o_r
h2o_c <=> h2o_m
h2o_n <=> h2o_c
h2o_c <=> h2o_x
h2o_c <=> h2o_v
3hxccoa_x + nad_x <=> 3ohxccoa_x + h_x + nadh_x
3odcoa_x + h_x + nadh_x <=> 3hdcoa_x + nad_x
3oddcoa_x + h_x + nadh_x <=> 3hddcoa_x + nad_x
3otdcoa_x + h_x + nadh_x <=> 3htdcoa_x + nad_x
3ohdcoa_x + h_x + nadh_x <=> 3hhdcoa_x + nad_x
3ohodcoa_x + h_x + nadh_x <=> 3hodcoa_x + nad_x
b124tc_m + h2o_m <=> hicit_m
4hbz_m + hexdp_m --> 3ophb_5_m + ppi_m
accoa_m + akg_m + h2o_m --> coa_m + h_m + hcit_m
accoa_n + akg_n + h2o_n --> coa_n + h_n + hcit_n
co2_c + h2o_c <=> h_c + hco3_c
co2_m + h2o_m <=> h_m + hco3_m
co2_n + h2o_n <=> h_n + hco3_n
hco3_c <=> hco3_n
amet_c + hcys_L_c --> ahcys_c + h_c + met_L_c
h_c + hcys_L_c <=> h_x + hcys_L_x
hdca_e --> hdca_c
hdcea_e --> hdcea_c
hemeO_m + nadh_m + o2_m --> h2o_m + hemeA_m + nad_m
frdp_m + h2o_m + pheme_m --> hemeO_m + ppi_m
4mhetz_c + atp_c --> 4mpetz_c + adp_c + h_c
atp_c + glc_D_c --> adp_c + g6p_c + h_c
atp_c + man_c --> adp_c + h_c + man6p_c
atp_c + fru_c --> adp_c + f6p_c + h_c
hexccoa_c <=> hexccoa_x
hexdp_c <=> hexdp_m
hgentis_c + o2_c --> 4mlacac_c + h_c
hicit_m + nad_m <=> h_m + nadh_m + oxag_m
h2o_c + histd_c + 2.0 nad_c --> 3.0 h_c + his_L_c + 2.0 nadh_c
h2o_c + hisp_c --> histd_c + pi_c
atp_c + his_L_c + trnahis_c --> amp_c + histrna_c + ppi_c
atp_m + his_L_m + trnahis_m --> amp_m + histrna_m + ppi_m
h_m + his_L_m <=> h_c + his_L_c
h_e + his_L_e <=> h_c + his_L_c
h_v + his_L_c --> h_c + his_L_v
h2o_c + hLkynr_c --> 3hanthrn_c + ala_L_c
h2o_c + 4.0 ppbng_c --> hmbil_c + 4.0 nh4_c
coa_c + mev_R_c + 2.0 nadp_c <=> 2.0 h_c + hmgcoa_c + 2.0 nadph_c
coa_c + h_c + hmgcoa_c <=> aacoa_c + accoa_c + h2o_c
coa_m + h_m + hmgcoa_m <=> aacoa_m + accoa_m + h2o_m
hmgcoa_c <=> hmgcoa_m
4ahmmp_c + atp_c --> 4ampm_c + adp_c + h_c
2ahhmp_m + atp_m --> 2ahhmd_m + amp_m + h_m
1p3h5c_c + 2.0 h_c + nadh_c --> 4hpro_LT_c + nad_c
1p3h5c_c + 2.0 h_c + nadph_c --> 4hpro_LT_c + nadp_c
4hpro_LT_m + nad_m --> 1p3h5c_m + 2.0 h_m + nadh_m
4hpro_LT_m + nadp_m --> 1p3h5c_m + 2.0 h_m + nadph_m
aspsa_c + h_c + nadh_c --> hom_L_c + nad_c
aspsa_c + h_c + nadph_c --> hom_L_c + nadp_c
accoa_c + hom_L_c <=> achms_c + coa_c
atp_c + hom_L_c --> adp_c + h_c + phom_c
glu_L_c + imacp_c --> akg_c + hisp_c
h_e + hxan_e <=> h_c + hxan_c
hxan_c + prpp_c --> imp_c + ppi_c
h2o_c + pyam5p_c --> pi_c + pydam_c
iamac_c --> iamac_e
iamoh_c <=> iamoh_e
iamoh_c <=> iamoh_m
ibutac_c --> ibutac_e
ibutoh_c <=> ibutoh_e
ibutoh_c <=> ibutoh_m
icit_m + nad_m --> akg_m + co2_m + nadh_m
icit_c + nadp_c --> akg_c + co2_c + nadph_c
icit_m + nadp_m --> akg_m + co2_m + nadph_m
icit_x + nadp_x --> akg_x + co2_x + nadph_x
icit_c --> glx_c + succ_c
id3acald_c <=> id3acald_e
id3acald_c <=> id3acald_m
gln_L_c + prlp_c --> aicar_c + eig3p_c + glu_L_c + h_c
eig3p_c --> h2o_c + imacp_c
2cpr5p_c + h_c --> 3ig3p_c + co2_c + h2o_c
akg_c + ile_L_c <=> 3mop_c + glu_L_c
akg_m + ile_L_m <=> 3mop_m + glu_L_m
atp_c + ile_L_c + trnaile_c --> amp_c + iletrna_c + ppi_c
atp_m + ile_L_m + trnaile_m --> amp_m + iletrna_m + ppi_m
h_e + ile_L_e <=> h_c + ile_L_c
h_v + ile_L_c --> h_c + ile_L_v
h_v + ile_L_v --> h_c + ile_L_c
ile_L_m --> ile_L_c
h2o_c + imp_c <=> fprica_c
h2o_c + imp_c + nad_c --> h_c + nadh_c + xmp_c
ind3ac_c <=> ind3ac_m
ind3eth_c <=> ind3eth_e
ind3eth_c <=> ind3eth_m
h_c + indpyr_c <=> co2_c + id3acald_c
atp_c + ins_c --> adp_c + h_c + imp_c
h_e + inost_e --> h_c + inost_c
h_e + ins_e --> h_c + ins_c
h2o_c + 0.01 ipc124_SC_c --> cer1_24_c + h_c + mi1p_D_c
h2o_c + 0.01 ipc126_SC_c --> cer1_26_c + h_c + mi1p_D_c
h2o_c + 0.01 ipc224_SC_c --> cer2_24_c + h_c + mi1p_D_c
h2o_c + 0.01 ipc226_SC_c --> cer2_26_c + h_c + mi1p_D_c
h2o_c + 0.01 ipc324_SC_c --> cer3_24_c + h_c + mi1p_D_c
h2o_c + 0.01 ipc326_SC_c --> cer3_26_c + h_c + mi1p_D_c
cer1_24_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 ipc124_SC_c
cer1_26_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 ipc126_SC_c
cer2_24_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 ipc224_SC_c
cer2_26_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 ipc226_SC_c
cer3_24_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 ipc324_SC_c
cer3_26_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 ipc326_SC_c
ipdp_c <=> dmpp_c
ipdp_c <=> ipdp_m
3c2hmp_c + nad_c --> 3c4mop_c + h_c + nadh_c
3c2hmp_c <=> 2ippm_c + h2o_c
2ippm_c + h2o_c <=> 3c3hmp_c
3mob_c + accoa_c + h2o_c --> 3c3hmp_c + coa_c + h_c
3mob_m + accoa_m + h2o_m --> 3c3hmp_m + coa_m + h_m
atp_m + coa_m + itacon_m <=> adp_m + itaccoa_m + pi_m
alac_S_m + h_m + nadph_m --> 23dhmb_m + nadp_m
2ahbut_m + h_m + nadph_m --> 23dhmp_m + nadp_m
Lkynr_c + h2o_c --> ala_L_c + anth_c + h_c
Lkynr_c + h_c + nadph_c + o2_c --> h2o_c + hLkynr_c + nadp_c
h_e + k_e <=> h_c + k_c
h_c + mthgxl_c + nadph_c --> lald_L_c + nadp_c
0.655 hdcoa_c + 0.01 hexccoa_c + 0.01 lanost_c + 0.27 odecoa_c + 0.02 pmtcoa_c + 0.03 stcoa_c + 0.015 tdcoa_c --> coa_c + 0.01 lanostest_SC_c
h2o_c + 0.01 lanostest_SC_c --> h_c + 0.02 hdca_c + 0.655 hdcea_c + 0.01 hexc_c + 0.01 lanost_c + 0.03 ocdca_c + 0.27 ocdcea_c + 0.015 ttdca_c
h2o_e + 0.01 lanostest_SC_e --> h_e + 0.02 hdca_e + 0.655 hdcea_e + 0.01 hexc_e + 0.01 lanost_e + 0.03 ocdca_e + 0.27 ocdcea_e + 0.015 ttdca_e
lanost_e <=> lanost_c
h2o_c + lald_L_c + nad_c --> 2.0 h_c + lac_L_c + nadh_c
Lcystin_v + h_v --> Lcystin_c + h_c
akg_c + leu_L_c <=> 4mop_c + glu_L_c
akg_m + leu_L_m <=> 4mop_m + glu_L_m
atp_c + leu_L_c + trnaleu_c --> amp_c + leutrna_c + ppi_c
atp_m + leu_L_m + trnaleu_m --> amp_m + leutrna_m + ppi_m
h_e + leu_L_e <=> h_c + leu_L_c
h_v + leu_L_c --> h_c + leu_L_v
h_v + leu_L_v --> h_c + leu_L_c
gthrd_c + mthgxl_c --> lgt_S_c
2.0 h_c + lanost_c + 3.0 nadph_c + 3.0 o2_c --> 44mctr_c + for_c + 4.0 h2o_c + 3.0 nadp_c
2.0 h_c + lanost_c + 3.0 nadh_c + 3.0 o2_c --> 44mctr_c + for_c + 4.0 h2o_c + 3.0 nad_c
Ssq23epx_c --> lanost_c
0.01 1agpc_SC_c + 0.02 dcacoa_c + 0.06 ddcacoa_c + 0.17 hdcoa_c + 0.09 ocdycacoa_c + 0.24 odecoa_c + 0.27 pmtcoa_c + 0.05 stcoa_c + 0.1 tdcoa_c --> coa_c + 0.01 pc_SC_c
0.01 dagpy_SC_c + h2o_c --> h_c + 0.01 pa_SC_c + pi_c
nadp_c + ser_L_c <=> 2amsa_c + h_c + nadph_c
atp_c + lys_L_c + trnalys_c --> amp_c + lystrna_c + ppi_c
atp_m + lys_L_m + trnalys_m --> amp_m + lystrna_m + ppi_m
h_c + lys_L_c <=> h_m + lys_L_m
h_e + lys_L_e <=> h_c + lys_L_c
h_v + lys_L_c --> h_c + lys_L_v
2.0 ficytc_m + lac_L_c --> 2.0 focytc_m + pyr_c
h_e + lac_L_e <=> h_c + lac_L_c
h_c + lac_L_c <=> h_m + lac_L_m
4mlacac_c --> 4fumacac_c
mal_L_x + oaa_c <=> mal_L_c + oaa_x
accoa_c + glx_c + h2o_c --> coa_c + h_c + mal_L_c
accoa_x + glx_x + h2o_x --> coa_x + h_x + mal_L_x
h2o_c + malt_c --> 2.0 glc_D_c
h_e + malt_e --> h_c + malt_c
h_e + mal_L_e <=> h_c + mal_L_c
mal_L_c + pi_m <=> mal_L_m + pi_c
gtp_c + h_c + man1p_c --> gdpmann_c + ppi_c
man6p_c <=> f6p_c
mannan_c <=> mannan_r
h_e + man_e --> h_c + man_c
hcit_m <=> b124tc_m + h2o_m
micit_m --> pyr_m + succ_m
h2o_m + oaa_m + ppcoa_m --> 2mcit_m + coa_m + h_m
ACP_c + malcoa_c <=> coa_c + malACP_c
ACP_m + malcoa_m <=> coa_m + malACP_m
mal_L_c + nad_c <=> h_c + nadh_c + oaa_c
mal_L_m + nad_m <=> h_m + nadh_m + oaa_m
mal_L_x + nad_x <=> h_x + nadh_x + oaa_x
5mdru1p_c --> dkmpp_c + h2o_c
mal_L_m + nad_m --> co2_m + nadh_m + pyr_m
mal_L_m + nadp_m --> co2_m + nadph_m + pyr_m
h_e + melib_e --> h_c + melib_c
h2o_c + melt_c <=> gal_c + sbt_D_c
atp_c + h2o_c + met_L_c --> amet_c + pi_c + ppi_c
achms_c + cys_L_c --> ac_c + cyst_L_c + h_c
5mthf_c + hcys_L_c --> h_c + met_L_c + thf_c
atp_c + met_L_c + trnamet_c --> amp_c + mettrna_c + ppi_c
atp_m + met_L_m + trnamet_m --> amp_m + mettrna_m + ppi_m
h_m + met_L_m <=> h_c + met_L_c
h_e + met_L_e <=> h_c + met_L_c
atp_c + mev_R_c --> 5pmev_c + adp_c + h_c
ctp_c + mev_R_c --> 5pmev_c + cdp_c + h_c
gtp_c + mev_R_c --> 5pmev_c + gdp_c + h_c
mev_R_c + utp_c --> 5pmev_c + h_c + udp_c
amet_c + 0.01 ptdmeeta_SC_c --> ahcys_c + h_c + 0.01 ptd2meeta_SC_c
dhap_c --> mthgxl_c + pi_c
hcys_L_c + mhpglu_c --> hpglu_c + met_L_c
atp_n + mi13456p_n --> adp_n + h_n + minohp_n
atp_n + mi1345p_n --> adp_n + h_n + mi13456p_n
atp_n + mi1456p_n --> adp_n + h_n + mi13456p_n
atp_n + mi145p_n --> adp_n + h_n + mi1456p_n
atp_n + mi145p_n --> adp_n + h_n + mi1345p_n
mi145p_c <=> mi145p_n
h2o_c + mi1p_D_c --> inost_c + pi_c
g6p_c --> mi1p_D_c
minohp_c <=> minohp_n
h2o_c + 0.01 mip2c124_SC_c --> cer1_24_c + h_c + man2mi1p_D_c
h2o_c + 0.01 mip2c126_SC_c --> cer1_26_c + h_c + man2mi1p_D_c
h2o_c + 0.01 mip2c224_SC_c --> cer2_24_c + h_c + man2mi1p_D_c
h2o_c + 0.01 mip2c226_SC_c --> cer2_26_c + h_c + man2mi1p_D_c
h2o_c + 0.01 mip2c324_SC_c --> cer3_24_c + h_c + man2mi1p_D_c
h2o_c + 0.01 mip2c326_SC_c --> cer3_26_c + h_c + man2mi1p_D_c
0.01 mipc124_SC_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 mip2c124_SC_c
0.01 mipc126_SC_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 mip2c126_SC_c
0.01 mipc224_SC_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 mip2c224_SC_c
0.01 mipc226_SC_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 mip2c226_SC_c
0.01 mipc324_SC_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 mip2c324_SC_c
0.01 mipc326_SC_c + 0.01 ptd1ino_SC_c --> 0.01 12dgr_SC_c + 0.01 mip2c326_SC_c
h2o_c + 0.01 mipc124_SC_c --> cer1_24_c + h_c + manmi1p_D_c
h2o_c + 0.01 mipc126_SC_c --> cer1_26_c + h_c + manmi1p_D_c
h2o_c + 0.01 mipc224_SC_c --> cer2_24_c + h_c + manmi1p_D_c
h2o_c + 0.01 mipc226_SC_c --> cer2_26_c + h_c + manmi1p_D_c
h2o_c + 0.01 mipc324_SC_c --> cer3_24_c + h_c + manmi1p_D_c
h2o_c + 0.01 mipc326_SC_c --> cer3_26_c + h_c + manmi1p_D_c
gdpmann_c + 0.01 ipc124_SC_c --> gdp_c + h_c + 0.01 mipc124_SC_c
gdpmann_c + 0.01 ipc126_SC_c --> gdp_c + h_c + 0.01 mipc126_SC_c
gdpmann_c + 0.01 ipc224_SC_c --> gdp_c + h_c + 0.01 mipc224_SC_c
gdpmann_c + 0.01 ipc226_SC_c --> gdp_c + h_c + 0.01 mipc226_SC_c
gdpmann_c + 0.01 ipc324_SC_c --> gdp_c + h_c + 0.01 mipc324_SC_c
gdpmann_c + 0.01 ipc326_SC_c --> gdp_c + h_c + 0.01 mipc326_SC_c
h_e + mmet_e --> h_c + mmet_c
3mob_c + h2o_c + mlthf_c --> 2dhp_c + thf_c
5mta_c + pi_c --> 5mdr1p_c + ade_c
h2o_c + methf_c <=> 10fthf_c + h_c
h2o_m + methf_m <=> 10fthf_m + h_m
mlthf_c + nadp_c <=> methf_c + nadph_c
mlthf_c + nad_c --> methf_c + nadh_c
mlthf_m + nadp_m <=> methf_m + nadph_m
2.0 h_c + mlthf_c + nadph_c --> 5mthf_c + nadp_c
5mdr1p_c <=> 5mdru1p_c
h2o_c + n4abutn_c + nad_c --> 4aabutn_c + 2.0 h_c + nadh_c
nac_e <=> nac_c
h2o_x + nad_x --> amp_x + 2.0 h_x + nmn_x
h_c + nadh_c + q6_m --> nad_c + q6h2_m
h_m + nadh_m + q6_m --> nad_m + q6h2_m
atp_c + nad_c --> adp_c + h_c + nadp_c
atp_m + nad_m --> adp_m + h_m + nadp_m
h2o_c + nad_c --> adprib_c + h_c + ncam_c
h2o_m + nad_m --> adprib_m + h_m + ncam_m
h2o_c + nadp_c --> nad_c + pi_c
h2o_m + nadp_m --> nad_m + pi_m
nadp_c <=> nadp_e
atp_c + dnad_c + nh4_c --> amp_c + h_c + nad_c + ppi_c
atp_n + dnad_n + nh4_n --> amp_n + h_n + nad_n + ppi_n
nad_n <=> nad_c
h_c + nac_c + prpp_c --> nicrnt_c + ppi_c
h_m + nac_m + prpp_m --> nicrnt_m + ppi_m
h_e + na1_c <=> h_c + na1_e
adp_c + h2o_c --> amp_c + h_c + pi_c
gdp_c + h2o_c --> gmp_c + h_c + pi_c
gdp_g + h2o_g --> gmp_g + h_g + pi_g
dgdp_c + h2o_c --> dgmp_c + h_c + pi_c
h2o_c + udp_c --> h_c + pi_c + ump_c
atp_c + gdp_c <=> adp_c + gtp_c
atp_c + udp_c <=> adp_c + utp_c
atp_c + cdp_c <=> adp_c + ctp_c
atp_c + dtdp_c <=> adp_c + dttp_c
atp_c + dgdp_c <=> adp_c + dgtp_c
atp_c + dudp_c <=> adp_c + dutp_c
atp_c + dcdp_c <=> adp_c + dctp_c
atp_c + dadp_c <=> adp_c + datp_c
atp_c + idp_c <=> adp_c + itp_c
Nbfortyr_c --> Nbfortyr_e
2.0 Nfortyr_c + h_c + nadph_c --> Nbfortyr_c + nadp_c
nh4_e <=> nh4_c
nh4_c --> nh4_e
nh4_c <=> nh4_m
nh4_c <=> nh4_n
nh4_c <=> nh4_x
atp_c + h_c + nmn_c --> nad_c + ppi_c
atp_m + h_m + nmn_m --> nad_m + ppi_m
h_e + nmn_e --> h_c + nmn_c
h_c + nmn_c <=> h_m + nmn_m
h_c + nmn_c <=> h_x + nmn_x
h2o_c + ncam_c <=> nac_c + nh4_c
h2o_m + ncam_m <=> nac_m + nh4_m
atp_c + h_c + nicrnt_c --> dnad_c + ppi_c
atp_m + h_m + nicrnt_m --> dnad_m + ppi_m
2.0 h_c + prpp_c + quln_c --> co2_c + nicrnt_c + ppi_c
2.0 h_m + prpp_m + quln_m --> co2_m + nicrnt_m + ppi_m
amet_c + ncam_c --> 1mncam_c + ahcys_c
dump_c + h2o_c --> duri_c + pi_c
h2o_c + xmp_c --> pi_c + xtsn_c
h2o_c + imp_c --> ins_c + pi_c
h2o_c + ump_c --> pi_c + uri_c
dcmp_c + h2o_c --> dcyt_c + pi_c
cmp_c + h2o_c --> cytd_c + pi_c
dtmp_c + h2o_c --> pi_c + thymd_c
damp_c + h2o_c --> dad_2_c + pi_c
amp_c + h2o_c --> adn_c + pi_c
dgmp_c + h2o_c --> dgsn_c + pi_c
gmp_c + h2o_c --> gsn_c + pi_c
gtp_c + h2o_c --> gdp_c + h_c + pi_c
dgtp_c + h2o_c --> dgdp_c + h_c + pi_c
2.0 h2o_c + ind3acnl_c --> ind3ac_c + nh4_c
aprop_c + 2.0 h2o_c --> ala_L_c + nh4_c
acybut_c + 2.0 h2o_c --> glu_L_c + nh4_c
o2_e <=> o2_c
o2_c <=> o2_r
o2_c <=> o2_m
oaa_c <=> oaa_e
h_c + oaa_c <=> h_m + oaa_m
2obut_m + coa_m + nad_m --> co2_m + nadh_m + ppcoa_m
cbp_c + orn_c --> citr_L_c + h_c + pi_c
ocdca_e --> ocdca_c
ocdcea_e --> ocdcea_c
ocdcya_e --> ocdcya_c
accoa_c + etoh_c --> aces_c + coa_c
accoa_c + iamoh_c --> coa_c + iamac_c
2mbtoh_c + accoa_c --> 2mbac_c + coa_c
accoa_c + ibutoh_c --> coa_c + ibutac_c
2phetoh_c + accoa_c --> coa_c + pheac_c
glu_L_c + ohpb_c <=> akg_c + phthr_c
3c4mop_c + h_c --> 4mop_c + co2_c
3c4mop_m + h_m --> 4mop_m + co2_m
h_c + orot5p_c --> co2_c + ump_c
h_c + orn_c --> co2_c + ptrc_c
akg_c + orn_c --> glu5sa_c + glu_L_c
acorn_m + glu_L_m --> acglu_m + orn_m
h_e + orn_e <=> h_c + orn_c
h_c + orn_m <=> h_m + orn_c
orot5p_c + ppi_c <=> orot_c + prpp_c
h_m + oxag_m <=> 2oxoadp_m + co2_m
akg_m + oxag_c <=> akg_c + oxag_m
1pyr5c_m + 2.0 h2o_m + nad_m --> glu_L_m + h_m + nadh_m
1pyr5c_c + 2.0 h_c + nadph_c --> nadp_c + pro_L_c
pacald_c <=> pacald_e
pacald_c <=> pacald_m
atp_c + 0.01 pa_SC_c --> adp_c + 0.01 dagpy_SC_c
pan4p_c <=> pan4p_m
ala_B_c + atp_c + pant_R_c --> amp_c + h_c + pnto_R_c + ppi_c
pant_R_c <=> pant_R_m
paps_c + trdrd_c --> 2.0 h_c + pap_c + so3_c + trdox_c
pap_e <=> pap_c
pap_c <=> pap_m
pa_SC_c <=> pa_SC_m
atp_c + hco3_c + pyr_c --> adp_c + h_c + oaa_c + pi_c
12dgr_SC_c + pc_SC_c --> 1agpc_SC_c + triglyc_SC_c
camp_c + h2o_c --> amp_c + h_c
35cdamp_c + h2o_c --> damp_c + h_c
35cimp_c + h2o_c --> h_c + imp_c
35cgmp_c + h2o_c --> gmp_c + h_c
35ccmp_c + h2o_c --> cmp_c + h_c
dhlam_m + nad_m --> h_m + lpam_m + nadh_m
coa_m + nad_m + pyr_m --> accoa_m + co2_m + nadh_m
o2_c + pdx5p_c <=> h2o2_c + pydx5p_c
pendp_c <=> pendp_m
accoa_c + pepd_c --> apep_c + coa_c + h_c
h_e + pepd_e --> h_c + pepd_c
ctp_c + ethamp_c + h_c --> cdpea_c + ppi_c
amet_c + 0.01 pe_SC_c --> ahcys_c + h_c + 0.01 ptdmeeta_SC_c
pe_SC_c <=> pe_SC_g
pe_SC_c <=> pe_SC_m
pe_SC_c <=> pe_SC_v
atp_c + f6p_c --> adp_c + fdp_c + h_c
atp_c + f6p_c --> adp_c + f26bp_c + h_c
atp_c + tag6p_D_c --> adp_c + h_c + tagdp_D_c
atp_c + s7p_c --> adp_c + h_c + s17bp_c
gam1p_c <=> gam6p_c
3pg_c + nad_c --> 3php_c + h_c + nadh_c
g6p_c <=> f6p_c
3pg_c + atp_c <=> 13dpg_c + adp_c
6pgl_c + h2o_c --> 6pgc_c + h_c
2pg_c <=> 3pg_c
g1p_c <=> g6p_c
h2o_m + 0.01 pgp_SC_m --> 0.01 pg_SC_m + pi_m
1p3h5c_m + 2.0 h2o_m + nad_m --> e4hglu_m + h_m + nadh_m
1p3h5c_m + h2o_m + h_m <=> 4hglusa_m
pheac_c --> pheac_e
akg_c + phe_L_c <=> glu_L_c + phpyr_c
atp_c + phe_L_c + trnaphe_c --> amp_c + phetrna_c + ppi_c
atp_m + phe_L_m + trnaphe_m --> amp_m + phetrna_m + ppi_m
h_m + phe_L_m <=> h_c + phe_L_c
h_e + phe_L_e <=> h_c + phe_L_c
h2o_c + 0.01 ptd135bp_SC_c --> pi_c + 0.01 ptd3ino_SC_c
atp_c + 0.01 ptd3ino_SC_c --> adp_c + h_c + 0.01 ptd134bp_SC_c
atp_c + 0.01 ptd3ino_SC_c --> adp_c + h_c + 0.01 ptd135bp_SC_c
h2o_c + 0.01 ptd145bp_SC_c --> pi_c + 0.01 ptd4ino_SC_c
h2o_c + 0.01 ptd145bp_SC_c --> 0.01 12dgr_SC_c + h_c + mi145p_c
atp_c + 0.01 ptd4ino_SC_c --> adp_c + h_c + 0.01 ptd145bp_SC_c
atp_c + 0.01 ptd1ino_SC_c --> adp_c + h_c + 0.01 ptd3ino_SC_c
atp_c + 0.01 ptd1ino_SC_c --> adp_c + h_c + 0.01 ptd4ino_SC_c
atp_n + 0.01 ptd1ino_SC_n --> adp_n + h_n + 0.01 ptd4ino_SC_n
0.01 cdpdag_SC_c + inost_c --> cmp_c + h_c + 0.01 ptd1ino_SC_c
h_c + pi_c <=> h_m + pi_m
h_c + pi_c <=> h_n + pi_n
h_c + pi_c <=> h_x + pi_x
h_e + pi_e <=> h_c + pi_c
h_c + pi_c <=> h_v + pi_v
oh1_m + pi_c <=> oh1_c + pi_m
h2o_e + 0.005 ptd1ino_SC_e --> 0.02 dca_e + 0.06 ddca_e + 0.5 g3pi_e + h_e + 0.27 hdca_e + 0.17 hdcea_e + 0.05 ocdca_e + 0.24 ocdcea_e + 0.09 ocdcya_e + 0.1 ttdca_e
h2o_c + 0.005 pc_SC_c --> 0.02 dca_c + 0.06 ddca_c + 0.5 g3pc_c + h_c + 0.27 hdca_c + 0.17 hdcea_c + 0.05 ocdca_c + 0.24 ocdcea_c + 0.09 ocdcya_c + 0.1 ttdca_c
h2o_e + 0.005 pc_SC_e --> 0.02 dca_e + 0.06 ddca_e + 0.5 g3pc_e + h_e + 0.27 hdca_e + 0.17 hdcea_e + 0.05 ocdca_e + 0.24 ocdcea_e + 0.09 ocdcya_e + 0.1 ttdca_e
h2o_c + 0.01 pc_SC_c --> chol_c + h_c + 0.01 pa_SC_c
man1p_c <=> man6p_c
5aprbu_c + h2o_c --> 4r5au_c + pi_c
amet_c + 0.01 ptd2meeta_SC_c --> ahcys_c + h_c + 0.01 pc_SC_c
5pmev_c + atp_c --> 5dpmev_c + adp_c
h2o_c + ppmi12346p_c --> h_c + minohp_c + pi_c
atp_c + minohp_c --> adp_c + ppmi12346p_c
h2o_c + ppmi1346p_c --> h_c + mi13456p_c + pi_c
atp_c + mi13456p_c --> adp_c + ppmi1346p_c
4ampm_c + atp_c --> 2mahmp_c + adp_c
pi_c + rnam_c <=> h_c + ncam_c + r1p_c
atp_c + pnto_R_c --> 4ppan_c + adp_c + h_c
h_e + pnto_R_e <=> h_c + pnto_R_c
N1aspmd_c + h2o_c + o2_c --> aproa_c + aprut_c + h2o2_c
N1sprm_c + h2o_c + o2_c --> N1aspmd_c + aproa_c + h2o2_c
h2o_c + o2_c + sprm_c --> aproa_c + h2o2_c + spmd_c
h2o_c + ppi_c --> h_c + 2.0 pi_c
h2o_m + ppi_m --> h_m + 2.0 pi_m
2.0 5aop_c --> 2.0 h2o_c + h_c + ppbng_c
4ppcys_c + h_c --> co2_c + pan4p_c
atp_c + oaa_c --> adp_c + co2_c + pep_c
r1p_c <=> r5p_c
4ppan_c + ctp_c + cys_L_c --> 4ppcys_c + cmp_c + h_c + ppi_c
nad_c + pphn_c --> 34hpp_c + co2_c + nadh_c
nadp_c + pphn_c --> 34hpp_c + co2_c + nadph_c
h_c + pphn_c --> co2_c + h2o_c + phpyr_c
pppg9_c <=> pppg9_m
3.0 o2_m + 2.0 pppg9_m --> 6.0 h2o_m + 2.0 ppp9_m
ipdp_m + pendp_m --> hexdp_m + ppi_m
h_c + phpyr_c --> co2_c + pacald_c
atp_c + gly_c + pram_c <=> adp_c + gar_c + h_c + pi_c
atp_c + fpram_c --> adp_c + air_c + 2.0 h_c + pi_c
pran_c --> 2cpr5p_c
h2o_c + prbamp_c --> prfp_c
5aizc_c + asp_L_c + atp_c <=> 25aics_c + adp_c + h_c + pi_c
h2o_c + prbatp_c --> h_c + ppi_c + prbamp_c
atp_c + fgam_c + gln_L_c + h2o_c --> adp_c + fpram_c + glu_L_c + h_c + pi_c
prfp_c --> prlp_c
nad_m + pro_L_m --> 1pyr5c_m + 2.0 h_m + nadh_m
atp_c + pro_L_c + trnapro_c --> amp_c + ppi_c + protrna_c
h_e + pro_L_e <=> h_c + pro_L_c
pro_L_c <=> pro_L_m
atp_c + r5p_c <=> amp_c + h_c + prpp_c
prpp_c <=> prpp_m
pep_c + skm5p_c --> 3psme_c + pi_c
h_g + 0.01 ps_SC_g --> co2_g + 0.01 pe_SC_g
h_m + 0.01 ps_SC_m --> co2_m + 0.01 pe_SC_m
h_v + 0.01 ps_SC_v --> co2_v + 0.01 pe_SC_v
0.01 cdpdag_SC_c + ser_L_c <=> cmp_c + h_c + 0.01 ps_SC_c
0.01 cdpdag_SC_m + ser_L_m <=> cmp_m + h_m + 0.01 ps_SC_m
3php_c + glu_L_c --> akg_c + pser_L_c
psph1p_c --> psph1p_r
psph1p_c --> 2hhxdal_c + ethamp_c
h_c + nadph_c + o2_c + sphgn_c --> h2o_c + nadp_c + psphings_c
h2o_c + pser_L_c --> pi_c + ser_L_c
ps_SC_c <=> ps_SC_g
ps_SC_c <=> ps_SC_m
ps_SC_c <=> ps_SC_v
ptd1ino_SC_c <=> ptd1ino_SC_n
ptd4ino_SC_c <=> ptd4ino_SC_n
dcacoa_x + h2o_x --> coa_x + dca_x + h_x
ddcacoa_x + h2o_x --> coa_x + ddca_x + h_x
h2o_x + ttccoa_x --> coa_x + h_x + ttc_x
h2o_x + pmtcoa_x --> coa_x + h_x + hdca_x
h2o_x + tdcoa_x --> coa_x + h_x + ttdca_x
h2o_x + stcoa_x --> coa_x + h_x + ocdca_x
h2o_x + occoa_x --> coa_x + h_x + octa_x
atp_c + h_c + pan4p_c --> dpcoa_c + ppi_c
atp_m + h_m + pan4p_m --> dpcoa_m + ppi_m
h_c + ptrc_e --> h_e + ptrc_c
ptrc_c --> ptrc_e
adn_c + pi_c <=> ade_c + r1p_c
adn_m + pi_m <=> ade_m + r1p_m
dad_2_c + pi_c <=> 2dr1p_c + ade_c
gsn_c + pi_c <=> gua_c + r1p_c
gsn_m + pi_m <=> gua_m + r1p_m
dgsn_c + pi_c <=> 2dr1p_c + gua_c
ins_c + pi_c <=> hxan_c + r1p_c
din_c + pi_c <=> 2dr1p_c + hxan_c
pi_c + xtsn_c <=> r1p_c + xan_c
h2o_c + o2_c + pyam5p_c --> h2o2_c + nh4_c + pydx5p_c
atp_c + pydam_c --> adp_c + h_c + pyam5p_c
atp_c + pydx_c --> adp_c + h_c + pydx5p_c
atp_c + pydxn_c --> adp_c + h_c + pdx5p_c
o2_c + pydxn_c <=> h2o2_c + pydx_c
2.0 h2o_c + nh4_c + 0.5 o2_c + pydx_c <=> 2.0 h2o2_c + pydam_c
adp_c + h_c + pep_c --> atp_c + pyr_c
pi_c + uri_c <=> r1p_c + ura_c
glu5sa_m + h2o_m + nadp_m --> glu_L_m + 2.0 h_m + nadph_m
h_c + pyr_c --> acald_c + co2_c
acald_c + h_c + pyr_c --> actn_R_c + co2_c
pyr_c --> pyr_e
h_e + pyr_e --> h_c + pyr_c
h_c + pyr_c <=> h_m + pyr_m
h_c + pyr_c <=> h_x + pyr_x
cmusa_c --> h2o_c + h_c + quln_c
dhap_c + iasp_c --> 2.0 h2o_c + pi_c + quln_c
quln_c <=> quln_m
h2o_c + raffin_c --> gal_c + sucr_c
atp_c + ribflv_c --> adp_c + fmn_c + h_c
atp_m + ribflv_m --> adp_m + fmn_m + h_m
4r5au_c + db4p_c --> dmlz_c + 2.0 h2o_c + pi_c
2.0 dmlz_c --> 4r5au_c + ribflv_c
atp_c + rib_D_c --> adp_c + h_c + r5p_c
h_e + ribflv_e --> h_c + ribflv_c
ribflv_c <=> ribflv_m
h_e + rib_D_e --> h_c + rib_D_c
adp_c + trdrd_c --> dadp_c + h2o_c + trdox_c
adp_n + trdrd_n --> dadp_n + h2o_n + trdox_n
gdp_c + trdrd_c --> dgdp_c + h2o_c + trdox_c
gdp_n + trdrd_n --> dgdp_n + h2o_n + trdox_n
cdp_c + trdrd_c --> dcdp_c + h2o_c + trdox_c
cdp_n + trdrd_n --> dcdp_n + h2o_n + trdox_n
trdrd_c + udp_c --> dudp_c + h2o_c + trdox_c
trdrd_n + udp_n --> dudp_n + h2o_n + trdox_n
atp_c + rnam_c --> adp_c + h_c + nmn_c
atp_c + trdrd_c --> datp_c + h2o_c + trdox_c
gtp_c + trdrd_c --> dgtp_c + h2o_c + trdox_c
ctp_c + trdrd_c --> dctp_c + h2o_c + trdox_c
trdrd_c + utp_c --> dutp_c + h2o_c + trdox_c
ru5p_D_c <=> xu5p_D_c
r5p_c <=> ru5p_D_c
L2aadp6sa_c + glu_L_c + h_c + nadph_c <=> h2o_c + nadp_c + saccrp_L_c
h2o_c + nad_c + saccrp_L_c <=> akg_c + h_c + lys_L_c + nadh_c
atp_c + h_c + so4_c --> aps_c + ppi_c
amet_c + zymst_c --> ahcys_c + fecost_c + h_c
h2o_r + sph1p_r --> pi_r + sphgn_r
h2o_r + psph1p_r --> pi_r + psphings_r
nad_c + sbt_D_c --> fru_c + h_c + nadh_c
nad_c + sbt_L_c --> h_c + nadh_c + srb_L_c
glc_D_c + h_c + nadph_c --> nadp_c + sbt_D_c
sbt_D_e <=> sbt_D_c
sbt_L_e <=> sbt_L_c
accoa_c + ser_L_c --> acser_c + coa_c
ser_L_c --> nh4_c + pyr_c
h_c + pmtcoa_c + ser_L_c --> 3dsphgn_c + co2_c + coa_c
atp_c + ser_L_c + trnaser_c --> amp_c + ppi_c + sertrna_c
h_c + ser_L_c <=> h_m + ser_L_m
h_e + ser_L_e <=> h_c + ser_L_c
Sfglutth_c + h2o_c <=> for_c + gthrd_c + h_c
dscl_c + nadp_c --> h_c + nadph_c + scl_c
fe2_c + scl_c --> 3.0 h_c + sheme_c
3dhsk_c + h_c + nadph_c --> nadp_c + skm_c
atp_c + skm_c --> adp_c + h_c + skm5p_c
cys_L_c + suchms_c --> cyst_L_c + h_c + succ_c
h2o_c + suchms_c <=> 2obut_c + h_c + nh4_c + succ_c
atp_c + sphgn_c --> adp_c + h_c + sph1p_c
atp_c + psphings_c --> adp_c + h_c + psph1p_c
adp_c + h_c + so4_c <=> aps_c + pi_c
so3_c --> so3_e
so4_e --> so4_c
sph1p_c --> sph1p_r
sph1p_c --> ethamp_c + hxdcal_c
accoa_c + spmd_c --> N1aspmd_c + coa_c + h_c
h_c + spmd_e --> h_e + spmd_c
spmd_c --> spmd_e
ametam_c + ptrc_c --> 5mta_c + h_c + spmd_c
ametam_c + spmd_c --> 5mta_c + h_c + sprm_c
h_c + sprm_e --> h_e + sprm_c
Ssq23epx_r <=> Ssq23epx_c
h_r + nadph_r + o2_r + sql_r --> Ssq23epx_r + h2o_r + nadp_r
h_r + nadh_r + o2_r + sql_r --> Ssq23epx_r + h2o_r + nad_r
2.0 frdp_c + h_c + nadph_c --> nadp_c + 2.0 ppi_c + sql_c
sql_c <=> sql_r
srb_L_e <=> srb_L_c
h2o_c + nadp_c + sucsal_c --> 2.0 h_c + nadph_c + succ_c
h_e + succ_e <=> h_c + succ_c
pi_m + succ_c --> pi_c + succ_m
fad_m + succ_m <=> fadh2_m + fum_m
q6_m + succ_m <=> fum_m + q6h2_m
fadh2_m + q6_m <=> fad_m + q6h2_m
fum_m + succ_c --> fum_c + succ_m
atp_m + coa_m + succ_m <=> adp_m + pi_m + succoa_m
h2o_e + sucr_e --> fru_e + glc_D_e
h_e + sucr_e --> h_c + sucr_c
3.0 h2o_c + h2s_c + 3.0 nadp_c <=> 5.0 h_c + 3.0 nadph_c + so3_c
34hpl_m --> T4hcinnm_m + h2o_m
h2o_c + 0.01 triglyc_SC_c --> 0.01 12dgr_SC_c + 0.02 dca_c + 0.06 ddca_c + h_c + 0.27 hdca_c + 0.17 hdcea_c + 0.05 ocdca_c + 0.24 ocdcea_c + 0.09 ocdcya_c + 0.1 ttdca_c
g3p_c + s7p_c <=> e4p_c + f6p_c
akg_c + o2_c + taur_c --> aacald_c + co2_c + h_c + so3_c + succ_c
taur_c <=> taur_e
atp_v + h2o_v + tchola_c --> adp_v + h_v + pi_v + tchola_v
h2o_m + methf_m --> 5fthf_m + h_m
atp_c + glu_L_c + thf_c <=> adp_c + h_c + pi_c + thfglu_c
h2o2_c + trdrd_c --> 2.0 h2o_c + trdox_c
h2o2_m + trdrd_m <=> 2.0 h2o_m + trdox_m
h2o2_n + trdrd_n --> 2.0 h2o_n + trdox_n
h2o2_x + trdrd_x <=> 2.0 h2o_x + trdox_x
2.0 h2o_e + thmpp_e --> h_e + 2.0 pi_e + thm_e
h_e + thymd_e --> h_c + thymd_c
h2o_c + thmmp_c --> pi_c + thm_c
thmpp_c --> thmpp_m
h2o_e + thmmp_e --> pi_e + thm_e
h_e + thm_e --> h_c + thm_c
athr_L_c --> acald_c + gly_c
thr_L_c --> acald_c + gly_c
thr_L_c --> 2obut_c + nh4_c
thr_L_m --> 2obut_m + nh4_m
h2o_c + phom_c --> pi_c + thr_L_c
atp_c + thr_L_c + trnathr_c --> amp_c + ppi_c + thrtrna_c
atp_m + thr_L_m + trnathr_m --> amp_m + ppi_m + thrtrna_m
h_c + thr_L_c <=> h_m + thr_L_m
h_e + thr_L_e <=> h_c + thr_L_c
h_e + thym_c <=> h_c + thym_e
achms_c + cys_L_c + gly_c + h_c + xu5p_D_c --> 4abut_c + 4mpetz_c + ac_c + co2_c + 3.0 h2o_c + nh4_c + pyr_c
achms_c + cys_L_c + gly_c + h_c + r5p_c --> 4abut_c + 4mpetz_c + ac_c + co2_c + 3.0 h2o_c + nh4_c + pyr_c
r5p_c + xu5p_D_c <=> g3p_c + s7p_c
e4p_c + xu5p_D_c <=> f6p_c + g3p_c
atp_c + thymd_c --> adp_c + dtmp_c + h_c
atp_c + thm_c --> amp_c + h_c + thmpp_c
pi_c + thymd_c <=> 2dr1p_c + thym_c
atp_c + thmpp_c --> adp_c + thmtp_c
dump_c + mlthf_c --> dhf_c + dtmp_c
h2o_c + thm_c --> 4ahmmp_c + 4mhetz_c + h_c
atp_c + thmmp_c <=> adp_c + thmpp_c
2mahmp_c + 4mpetz_c + h_c --> ppi_c + thmmp_c
dhap_c <=> g3p_c
trdox_c <=> trdox_x
h_c + nadph_c + trdox_c --> nadp_c + trdrd_c
trdrd_c <=> trdrd_x
h_m + nadph_m + trdox_m --> nadp_m + trdrd_m
h2o_c + tre6p_c --> pi_c + tre_c
g6p_c + udpg_c --> h_c + tre6p_c + udp_c
h2o_c + tre_c --> 2.0 glc_D_c
h2o_v + tre_v --> 2.0 glc_D_v
h_e + tre_e --> h_c + tre_c
h_c + tre_c <=> h_v + tre_v
0.01 12dgr_SC_c + 0.02 dcacoa_c + 0.06 ddcacoa_c + 0.17 hdcoa_c + 0.09 ocdycacoa_c + 0.24 odecoa_c + 0.27 pmtcoa_c + 0.05 stcoa_c + 0.1 tdcoa_c --> coa_c + 0.01 triglyc_SC_c
o2_c + trp_L_c --> Lfmkynr_c
3ig3p_c + ser_L_c --> g3p_c + h2o_c + trp_L_c
akg_c + trp_L_c <=> glu_L_c + indpyr_c
atp_c + trnatrp_c + trp_L_c --> amp_c + ppi_c + trptrna_c
atp_m + trnatrp_m + trp_L_m --> amp_m + ppi_m + trptrna_m
h_c + trp_L_c <=> h_m + trp_L_m
h_e + trp_L_e <=> h_c + trp_L_c
ttccoa_c <=> ttccoa_x
ttdca_e <=> ttdca_c
10fthf_c + tyr_L_c --> Nfortyr_c + h_c + thf_c
34hpp_c + glu_L_c --> akg_c + tyr_L_c
34hpp_m + glu_L_m --> akg_m + tyr_L_m
34hpp_x + glu_L_x --> akg_x + tyr_L_x
atp_c + trnatyr_c + tyr_L_c --> amp_c + ppi_c + tyrtrna_c
atp_m + trnatyr_m + tyr_L_m --> amp_m + ppi_m + tyrtrna_m
h_c + tyr_L_c <=> h_m + tyr_L_m
h_c + tyr_L_c <=> h_x + tyr_L_x
h_e + tyr_L_e <=> h_c + tyr_L_c
h_v + tyr_L_c --> h_c + tyr_L_v
h_v + tyr_L_v --> h_c + tyr_L_c
acgam1p_c + h_c + utp_c <=> ppi_c + udpacgal_c
udpg_c <=> udpgal_c
udpgal_c --> udpgal_g
gal1p_c + udpg_c <=> g1p_c + udpgal_c
h2o_c + 2.0 h_c + urdglyc_c <=> co2_c + glx_c + 2.0 nh4_c
atp_c + ump_c <=> adp_c + udp_c
atp_n + ump_n <=> adp_n + udp_n
ump_c <=> ump_n
2kmb_c + glu_L_c --> akg_c + met_L_c
2.0 amet_c + uppg3_c --> 2.0 ahcys_c + dscl_c + h_c
hmbil_c --> h2o_c + uppg3_c
4.0 h_c + uppg3_c --> 4.0 co2_c + cpppg3_c
prpp_c + ura_c --> ppi_c + ump_c
h_e + ura_e --> h_c + ura_c
2.0 h_e + urea_e <=> 2.0 h_c + urea_c
atp_c + hco3_c + urea_c <=> adp_c + allphn_c + h_c + pi_c
atp_c + dump_c <=> adp_c + dudp_c
atp_n + dump_n <=> adp_n + dudp_n
atp_c + uri_c --> adp_c + h_c + ump_c
gtp_c + uri_c --> gdp_c + h_c + ump_c
h_e + uri_e --> h_c + uri_c
2.0 h2o_c + utp_c --> 2.0 h_c + 2.0 pi_c + ump_c
2.0 h_c + ump_m + utp_c --> 2.0 h_m + ump_c + utp_m
akg_c + val_L_c <=> 3mob_c + glu_L_c
akg_m + val_L_m --> 3mob_m + glu_L_m
atp_c + trnaval_c + val_L_c --> amp_c + ppi_c + valtrna_c
atp_m + trnaval_m + val_L_m --> amp_m + ppi_m + valtrna_m
h_c + val_L_c <=> h_m + val_L_m
h_e + val_L_e <=> h_c + val_L_c
xan_e <=> xan_c
prpp_c + xan_c --> ppi_c + xmp_c
h_e + xtsn_e --> h_c + xtsn_c
atp_c + xylu_D_c --> adp_c + h_c + xu5p_D_c
h_c + nadph_c + xyl_D_c --> nadp_c + xylt_c
nad_c + xylt_c --> h_c + nadh_c + xylu_D_c
xylt_e <=> xylt_c
xyl_D_e <=> xyl_D_c
r5p_c + ura_c <=> h2o_c + psd5p_c
0.655 hdcoa_c + 0.01 hexccoa_c + 0.27 odecoa_c + 0.02 pmtcoa_c + 0.03 stcoa_c + 0.015 tdcoa_c + 0.01 zymst_c --> coa_c + 0.01 zymstest_SC_c
h2o_c + 0.01 zymstest_SC_c --> h_c + 0.02 hdca_c + 0.655 hdcea_c + 0.01 hexc_c + 0.03 ocdca_c + 0.27 ocdcea_c + 0.015 ttdca_c + 0.01 zymst_c
h2o_e + 0.01 zymstest_SC_e --> h_e + 0.02 hdca_e + 0.655 hdcea_e + 0.01 hexc_e + 0.03 ocdca_e + 0.27 ocdcea_e + 0.015 ttdca_e + 0.01 zymst_e
zymst_e <=> zymst_c
1.1348 13BDglcn_c + 0.4588 ala_L_c + 0.046 amp_c + 0.1607 arg_L_c + 0.1017 asn_L_c + 0.2975 asp_L_c + 59.276 atp_c + 0.0447 cmp_c + 0.0066 cys_L_c + 0.0036 damp_c + 0.0024 dcmp_c + 0.0024 dgmp_c + 0.0036 dtmp_c + 0.0007 ergst_c + 0.1054 gln_L_c + 0.3018 glu_L_c + 0.2904 gly_c + 0.5185 glycogen_c + 0.046 gmp_c + 59.276 h2o_c + 0.0663 his_L_c + 0.1927 ile_L_c + 0.2964 leu_L_c + 0.2862 lys_L_c + 0.8079 mannan_c + 0.0507 met_L_c + 6e-06 pa_SC_c + 6e-05 pc_SC_c + 4.5e-05 pe_SC_c + 0.1339 phe_L_c + 0.1647 pro_L_c + 1.7e-05 ps_SC_c + 5.3e-05 ptd1ino_SC_c + 0.00099 ribflv_c + 0.1854 ser_L_c + 0.02 so4_c + 0.1914 thr_L_c + 0.0234 tre_c + 6.6e-05 triglyc_SC_c + 0.0284 trp_L_c + 0.102 tyr_L_c + 0.0599 ump_c + 0.2646 val_L_c + 0.0015 zymst_c --> 59.276 adp_c + 58.70001 h_c + 59.305 pi_c

Models in Minho database have been manually verified if they can be used to run simulations as described in the publications.

models.minho.validated.VvuMBEL943 # use TAB completion to see the other models
Name HyunUkKim2010_VvuMBEL943_MetabolicModeling
Number of metabolites 912
Number of reactions 1019
Reactions
2.0 ATP + CO2 + GLN --> 2.0 ADP + CAP + GLU + PI
GLU --> CO2 + GABA
AKG + GLN + NADPH --> 2.0 GLU + NADP
NADMA + UDP <=> UDPNADMA
ATP + GLU + NH3 --> ADP + GLN + PI
NANEU9P + PI <=> NADMA6P + PEP
PI + URI <=> R1P + URA
NAGA6P <=> NADMA6P
DCMP --> DUMP + NH3
ATP + NADMA --> ADP + NADMA6P
CYTD --> NH3 + URI
NADMA + PI <=> NADMA6P
DC --> DU + NH3
CT --> NH3 + URA
a_5MC <=> NH3 + TM
NANEU <=> NADMA + PYR
NANEU + PI <=> NADMA + PEP
UDPNAG <=> UDPNADMA
2.0 NAD + UDPNADMA --> 2.0 NADH + UDPNADMAU
UDPNAG <=> NADMA + UDP
ATP + PYR --> AMP + PEP + PI
DTDPGLU <=> DTDPGLAC
ACCOA + PI <=> ACETYLP + COA
HSERxt --> HSERxt_b
NADH + PYR <=> LAC + NAD
SLACxt --> SLACxt_b
CTP + NANEU <=> CMPNANEU + PPI
CTP + NGNEU <=> CMPNGNEU + PPI
2.0 NAD + UDPGAL --> 2.0 NADH + UDPDGALAC
DTDPGLU + 2.0 NADP --> DTDPDGLUC + 2.0 NADPH
PEP + UDPNAG --> PI + UDPNAGEP
NADPH + UDPNAGEP --> NADP + UDPNAM
CYTD + DTTP --> CMP + DTDP
DGTP + URI --> DGDP + UMP
CYTD + DGTP --> CMP + DGDP
DCTP + URI --> DCDP + UMP
CYTD + GTP --> CMP + GDP
DUTP + URI --> DUDP + UMP
CYTD + DUTP --> CMP + DUDP
DTTP + URI --> DTDP + UMP
CYTD + DCTP --> CMP + DCDP
HISxt --> HISxt_b
GTP + URI --> GDP + UMP
NO2xt <=> NO2xt_b
O2xt <=> O2xt_b
ILExt --> ILExt_b
URI + UTP --> UDP + UMP
GA6P --> F6P + NH3
CYTD + UTP --> CMP + UDP
F6P + GLN --> GA6P + GLU
CMP --> CYTD + PI
GA6P <=> GA1P
UMP --> PI + URI
NAGA6P <=> AC + GA6P
NAGA1P + UTP <=> PPI + UDPNAG
DTMP --> DT + PI
DCMP --> DC + PI
ACCOA + GA1P --> COA + NAGA1P
a_23cUMP --> a_3UMP
a_23cCMP --> a_3CMP
ITP + URI --> IDP + UMP
CYTD + ITP --> CMP + IDP
SUC --> FRU + GLC
CB --> 2.0 bDGLC
TRE6P --> G6P + GLC
2.0 STA --> DEXTRIN
ATP + DU --> ADP + DUMP
PRPP + URA <=> PPI + UMP
NADPH + OTHIO --> NADP + RTHIO
ATP + DCMP <=> ADP + DCDP
ATP + DTDP <=> ADP + DTTP
ATP + CMP <=> ADP + CDP
NAD + a_2P1A --> NADH + PPN
ATP + DTMP <=> ADP + DTDP
NAD + a_2HBA --> NADH + OBUT
COA + OBUT <=> FORMATE + PPACOA
PI + PPACOA <=> COA + PROPIONYLP
ATP + PROPANOATE <=> ADP + PROPIONYLP
COA + PPA <=> AMP + PPACOA
DU + PI --> DR1P + URA
ATP + PROPANOATE <=> PPA + PPI
DUMP + METTHF --> DHF + DTMP
a_3HPCOA <=> PPCOA
R5P + URA <=> PURI5P
AKG + bALA <=> GLU + a_3OPP
a_2PPG --> GLYCOLATE + PI
URAxt --> URAxt_b
CTP + RTHIO --> DCTP + OTHIO
ATP + DUMP <=> ADP + DUDP
ATP + CYTD --> ADP + CMP
ATP + URI --> ADP + UMP
DT + PI --> DR1P + TM
ATP + DUDP <=> ADP + DUTP
RTHIO + UDP --> DUDP + OTHIO
RTHIO + UTP --> DUTP + OTHIO
a_3HBCOA <=> R3HBCOA
NADP + R3HBCOA <=> AACCOA + NADPH
BUTANAL + COA + NAD --> C040COA + NADH
a_3HBCOA <=> CCOA
PYR + THMPP --> CO2 + a_2HETPP
DATP + URI --> DADP + UMP
CYTD + DATP --> CMP + DADP
COA + MMSA + NAD --> CO2 + NADH + PPACOA
NAD + a_3HBCOA <=> AACCOA + NADH
PYR + a_2HETPP --> ACLAC + THMPP
a_3HB123TC <=> PYR + SUCC
COA + a_2MCIT <=> OA + PPACOA
FRUxt --> FRUxt_b
ACCOA + FORMATE <=> COA + PYR
GTP + RTHIO --> DGTP + OTHIO
MAL + NADP <=> CO2 + NADPH + PYR
OA --> CO2 + PYR
PPI + XMP <=> PRPP + XAN
pppGpp <=> PI + ppGpp
ATP + DAMP <=> ADP + DADP
GMP + PPI <=> GN + PRPP
ACETYLP + ADP <=> AC + ATP
DOROA + UQ <=> OROA + UQH2
AC + ATP <=> AAD + PPI
CAASP <=> DOROA
AAD + COA <=> ACCOA + AMP
ASP + CAP --> CAASP + PI
AppppA --> 2.0 ADP
MAL + NAD <=> CO2 + NADH + PYR
ATP + OA <=> ADP + CO2 + PEP
CO2 + PEP --> OA + PI
ACETYLP --> AC + PI
DOROA + MK <=> MKH2 + OROA
ATP + FORMATE + THF --> ADP + FTHF + PI
GLAL + NAD --> GLYCOLATE + NADH
OROA + PRPP <=> OMP + PPI
OMP --> CO2 + UMP
ATP + UMP <=> ADP + UDP
ATP + UDP <=> ADP + UTP
ATP + GLN + UTP --> ADP + CTP + GLU + PI
ATP + NH3 + UTP --> ADP + CTP + PI
2.0 ACCOA --> AACCOA + COA
CDP + RTHIO --> DCDP + OTHIO
ACCOA + GLX --> COA + MAL
ATP + CDP <=> ADP + CTP
MTG + RGT <=> LTG
ATP + DT --> ADP + DTMP
DHAP --> MTG + PI
ATP + DCDP <=> ADP + DCTP
ACAL + COA + NAD <=> ACCOA + NADH
LTG --> LAC + RGT
FORMATE + NAD --> CO2 + NADH
ICIT --> GLX + SUCC
GSNxt --> GSNxt_b
ATP + SLF --> APS + PPI
APS + ATP --> ADP + PAPS
PAPS + RTHIO --> H2SO3 + OTHIO + PAP
H2SO3 + 3.0 NADPH --> H2S + 3.0 NADP
ASP <=> FUM + NH3
ACCOA + ACP --> ACACP + COA
PAP --> AMP + PI
3.0 NADP + SELT --> 3.0 NADPH + SELD
ACCOA + ATP + CO2 --> ADP + MALCOA + PI
ACP + MALCOA --> COA + MALACP
NADPH + NAGLUP --> NADP + NAGLUS + PI
AG --> CO2 + PHE
ATP + NAGLU --> ADP + NAGLUP
ACCOA + GLU --> COA + NAGLU
NAD + PRO <=> NADH + P5C
NADPH + P5C <=> NADP + PRO
GLUGSAL <=> P5C
GLUP + NADPH --> GLUGSAL + NADP + PI
ATP + GLU --> ADP + GLUP
O2 + PHE + THBPT --> DHBPT + TYR
GLU + a_4HPP --> AKG + TYR
ATP + TRNATYR + TYR --> AMP + PPI + TRYTRNATYR
DAxt --> DAxt_b
NAD + a_1BOH <=> BUTANAL + NADH
NAD + SUCCSA --> NADH + SUCC
NADP + SUCCSA --> NADPH + SUCC
AKG + GABA <=> GLU + SUCCSA
a_3H3MGCOA --> AAC + ACCOA
NAD + a_3B1A --> NADH + a_3BUT
COA + NAD + a_3OPP --> ACCOA + CO2 + NADH
NADH + UQ --> NAD + UQH2
MK + NADH --> MKH2 + NAD
DCxt --> DCxt_b
DMK + NADH --> DMKH2 + NAD
URIxt --> URIxt_b
IGP + SER --> G3P + TRP
CPAD5P --> CO2 + IGP
G3P + INDOLE <=> IGP
INDOLE + SER --> TRP
PHEN --> CO2 + PHPYR
CHOR <=> PHEN
NAD + PHEN --> CO2 + NADH + a_4HPP
ATP + PHE + TRNAPHE --> AMP + PHETRNAPHE + PPI
NPRAN --> CPAD5P
CHOR + NH3 --> AN + PYR
AN + PRPP --> NPRAN + PPI
PPI --> 2.0 PI
ADP + 4.0 Hxt + PI <=> ATP
FADH2 + UQ --> FAD + UQH2
0.5 O2 + UQH2 --> 2.0 Hxt + UQ
FEROC + NO3 --> FERIC + NO2
3.0 NADH + NO2 --> 3.0 NAD + NH3
CO2 + METTHF + NADH + NH3 --> GLY + NAD + THF
CO2 --> H2CO3
BIOMASSxt --> BIOMASSxt_b
3.0 NADPH + NO2 --> 3.0 NADP + NH3
6.0 FEROC + NO2 --> 6.0 FERIC + NH3
TRExt --> TRExt_b
DHSK + NADPH --> NADP + SME
DHSK <=> a_34DHB
DQT --> DHSK
CHOR + GLN --> AN + GLU + PYR
a_3PSME --> CHOR + PI
PEP + SME3P --> PI + a_3PSME
ATP + SME --> ADP + SME3P
SLFxt <=> SLFxt_b
a_3PGxt --> a_3PGxt_b
GLYCOLATExt --> GLYCOLATExt_b
CTxt --> CTxt_b
LYSxt --> LYSxt_b
MALxt --> MALxt_b
PTRCxt --> PTRCxt_b
THIAMINxt <=> THIAMINxt_b
C140ACP + UDPNAG --> ACP + UDPG2AA
RGT --> CYSGLY + GLU
UDPG2AA --> AC + UDPG2A
C140ACP + UDPG2A --> ACP + UDPG23A
UDPG23A --> LIPX + UMP
LIPX + UDPG23A --> DISAC1P + UDP
ATP + DISAC1P --> ADP + LIPIV
CMPKDO + LIPIV --> CMP + KDOLIPIV
CMPKDO + KDOLIPIV --> CMP + K2LIPIV
C120ACP + K2LIPIV --> ACP + LK2LIPIV
KDOP --> KDO + PI
A5P + PEP --> KDOP + PI
C140ACP + LK2LIPIV --> ACP + K2LIPA
UREAxt --> UREAxt_b
ATP + DGDMH7P --> ADP + DGDMH17BP
DGDMH17BP --> DGDMH1P + PI
CTP + KDO --> CMPKDO + PPI
S7P --> DGDMH7P
0.387 ADPHEP + 0.09 F6P + 1.149 UDPG + 0.142 UDPNAG --> 0.387 ADP + LPS + 0.09 PI + 1.291 UDP
ATP + DGDMH1P --> ADPDGDMHEP + PPI
ADPDGDMHEP --> ADPHEP
Hxt + LYSxt --> LYS
ATP + LYSxt --> ADP + LYS + PI
ATP + METxt --> ADP + MET + PI
Hxt + MET <=> METxt
ATP + LEUxt --> ADP + LEU + PI
OPHSER + SCYS --> PI + SLLCT
AHSER + SCYS --> AC + SLLCT
Hxt + LEUxt --> LEU
SCYS + SHSER --> SLLCT + SUCC
Hxt + LYS <=> LYSxt
SLLCT --> NH3 + PYR + SHCYS
Hxt + LYS --> LYSxt
ALA + NAD --> NADH + NH3 + PYR
GLU + PPYR <=> AKG + a_2A3PP
Hxt + ILExt --> ILE
PYR + a_2AEP <=> ALA + PPAC
Hxt + LEU <=> LEUxt
MCB + PPAC --> VB12 + a_2HPP
PHExt --> PHExt_b
ATP + SMET + TRNAMET --> AMP + PPI + SMETTRNAMET
ATP + SMET --> PI + PPI + SeASMET
ASER + SELD --> AC + SCYS
ALA <=> DALA
ATP + 2.0 DALA --> ADP + ALAALA + PI
DGLN --> DGLU + NH3
DGLU <=> GLU
CGS --> CHD + GLC
GLN --> GLU + NH3
ATP + SELNT <=> ASELNT + PPI
ASELNT + ATP --> ADP + a_3PASELNT
CYSGLY --> CYS + GLY
a_2PGxt --> a_2PGxt_b
GLN + Hxt <=> GLNxt
ATP + GLNxt --> ADP + GLN + PI
A6RP5P + NADPH --> A6RP5P2 + NADP
GLNxt + Hxt --> GLN
A6RP5P2 --> A6RP + PI
GLU + Hxt <=> GLUxt
RL5P --> DB4P + FORMATE
ATP + GLUxt --> ADP + GLU + PI
GLUxt + Hxt --> GLU
CITxt --> CITxt_b
A6RP + DB4P --> D8RL + PI
2.0 D8RL --> A6RP + RIBFLAV
ATP + RIBFLAV --> ADP + FMN
FMN --> PI + RIBFLAV
ATP + FMN --> FAD + PPI
E4P + NAD <=> ER4P + NADH
DMB + NACN --> N15PADRDMB + NAC
CYSxt + Hxt --> CYS
ATP + CYSxt --> ADP + CYS + PI
DGLUxt + Hxt --> DGLU
DALAxt + Hxt --> DALA
HISxt + Hxt --> HIS
GLU + OHB <=> AKG + PHT
Hxt + ILE <=> ILExt
PHT --> PI + a_4HLT
HIS + Hxt <=> HISxt
ATP + HISxt --> ADP + HIS + PI
ER4P + NAD <=> NADH + OHB
ATP + PYRDX --> ADP + P5P
P5P --> PI + PYRDX
ATP + ILExt --> ADP + ILE + PI
NAD + PHT --> CO2 + NADH + a_3A2OP
DX5P + a_3A2OP --> P5P + PI
LEUxt --> LEUxt_b
GLUxt + Naxt --> GLU + Na
ATP + PL --> ADP + PL5P
PL5P --> PI + PL
O2 + P5P --> H2O2 + PL5P
GLYxt + Naxt --> GLY + Na
GLYxt + Hxt --> GLY
ATP + GLYxt --> ADP + GLY + PI
GLY + Hxt <=> GLYxt
ALA + Hxt <=> ALAxt
ALA + ATP + UDPNAM --> ADP + PI + UDPNAMA
ATP + DGLU + UDPNAMA --> ADP + PI + UDPNAMAG
ALAxt + ATP --> ADP + ALA + PI
SPRMDxt --> SPRMDxt_b
ATP + MDAPIM + UDPNAMAG --> ADP + PI + UDPMNLADGMD
ALAxt + Hxt --> ALA
ALAALA + ATP + UDPMNLADGMD --> ADP + PI + UDPMNLADGMDDADA
ALAxt + Naxt --> ALA + Na
Naxt + SLFxt --> Na + SLF
Hxt + SLFxt --> SLF
ATP + SLFxt --> ADP + PI + SLF
ATP + THIAMINxt --> ADP + PI + THIAMIN
DALA + PPEPTIDO --> DALAxt + PEPTIDO
UPPMNGNLADGNMDG5DADA --> PPEPTIDO + UDCPP
GLUxt --> GLUxt_b
ATP + PIxt --> ADP + 2.0 PI
3.0 Naxt + PIxt <=> 3.0 Na + PI
UDPNAG + UPPMNLADGMDDADA --> UDP + UPPMNGNLADGMDDADA
UDCP + UDPMNLADGMDDADA --> UMP + UPPMNLADGMDDADA
5.0 GLY + UPPMNGNLADGNMDDADA --> UPPMNGNLADGNMDG5DADA
ATP + NH3 + UPPMNGNLADGMDDADA --> ADP + PI + UPPMNGNLADGNMDDADA
AHM + ATP --> ADP + AHMP
CYS + Hxt <=> CYSxt
AHMP + ATP --> ADP + AHMPP
ASPxt + ATP --> ADP + ASP + PI
ACALA --> ACMUR + ALA
AIR --> AHM
ASPxt + Hxt --> ASP
ASNxt + Hxt --> ASN
ASP + Hxt <=> ASPxt
UDCPP --> PI + UDCP
ASN + Hxt <=> ASNxt
ASNxt + ATP --> ADP + ASN + PI
GLUCxt --> GLUCxt_b
ARGxt + Hxt --> ARG
ARGxt + ATP --> ADP + ARG + PI
ARG + Hxt <=> ARGxt
ORNxt --> ORNxt_b
D6RP5P --> A6RP5P + NH3
GTP --> D6RP5P + FORMATE + PPI
ATP + THMP <=> ADP + THMPP
THMP <=> PI + THIAMIN
AHMPP + THZP --> PPI + THMP
CYS + OAHSER <=> AC + LLCT
H2S + OAHSER --> AC + HCYS
H2S + OSLHSER --> HCYS + SUCC
OSLHSER --> NH3 + OBUT + SUCC
HO3S2 + OAHSER + RTHIO --> AC + H2SO3 + HCYS + OTHIO
BAL + FAD --> BETAINE + FADH2
ATP <=> ADP + Hxt + PI
GLYCOLATExt <=> GLYCOLATE
CYS + OSLHSER --> LLCT + SUCC
HSER + SUCCOA <=> COA + OSLHSER
MTG + NADPH --> HAC + NADP
BAL + NAD --> BETAINE + NADH
Hxt + SLACxt --> SLAC
MALxt + SUCC <=> MAL + SUCCxt
MALxt + Naxt --> MAL + Na
ADNxt --> ADNxt_b
Hxt + MALxt --> MAL
ATP + GL3Pxt --> ADP + GL3P + PI
GL3Pxt + PI <=> GL3P + PIxt
Naxt + SUCCxt --> Na + SUCC
Hxt + SUCCxt --> SUCC
CO2xt <=> CO2
THR --> NH3 + OBUT
SER + THMNP <=> GLY + MTHMNP
ATP + THR + TRNATHR --> AMP + PPI + THRTRNATHR
ATP + SER + TRNASER --> AMP + PPI + SERTRNASER
ATP + GLY + TRNAGLY --> AMP + GLYTRNAGLY + PPI
ASPSA + GLU --> AKG + a_24DAB
Hxt + PIxt <=> PI
DHLIPOYLPROTEIN + NAD --> LIPOYLPROTEIN + NADH
GLY + LIPOYLPROTEIN --> CO2 + SAP
SER <=> NH3 + PYR
SER --> NH3 + PYR
2.0 Hxt + Na <=> Naxt
Naxt <=> Hxt + Na
3.0 Hxt + 2.0 Na <=> 2.0 Naxt
3.0 Hxt + Na <=> Naxt
NO2 --> NO2xt
NH3xt <=> NH3
O2xt <=> O2
ATP + NO3xt --> ADP + NO3 + PI
ASPxt --> ASPxt_b
CYSxt --> CYSxt_b
SUCCxt --> SUCCxt_b
SAP + THF --> DHLIPOYLPROTEIN + METTHF + NH3
MELIxt --> MELIxt_b
ACCOA + GLY <=> COA + a_2A3OB
NAD + THR --> NADH + a_2A3OB
THR <=> ACAL + GLY
ATHR <=> ACAL + GLY
a_3PSER --> PI + SER
SER + THF <=> GLY + METTHF
GLU + PHP --> AKG + a_3PSER
NAD + a_3PG --> NADH + PHP
PHSER --> PI + THR
ATP + a_2PGxt --> ADP + PI + a_2PG
PEP + TRExt --> PYR + TRE6P
PEP + SUCxt --> PYR + SUC6P
NAGAxt + PEP --> NAGA6P + PYR
MNTxt + PEP --> MNT1P + PYR
MELIxt + Naxt --> MELI + Na
Hxt + MELIxt --> MELI
ATP + MLTxt --> ADP + MLT + PI
GLUCxt + Hxt --> GLUC
GLCxt + PEP --> G6P + PYR
BASP + NADPH --> ASPSA + NADP + PI
ASPSA + NADH <=> HSER + NAD
ASPSA + NADPH <=> HSER + NADP
ATP + HSER --> ADP + PHSER
GLU + PYR <=> AKG + ALA
ASP --> CO2 + bALA
CNS --> HIS + bALA
ASP + ATP --> ADP + BASP
ASN --> ASP + NH3
ASP + ATP + GLN --> AMP + ASN + GLU + PPI
FUMxt + SUCC <=> FUM + SUCCxt
FUMxt + Naxt --> FUM + Na
ICITxt + Naxt --> ICIT + Na
CITxt + Naxt --> CIT + Na
CITxt <=> CIT
FUMxt + Hxt --> FUM
FORMATE --> FORMATExt
ATP + a_3PGxt --> ADP + PI + a_3PG
AKGxt + Hxt --> AKG
AC <=> ACxt + Hxt
NAD + 2.0 RGT <=> NADH + OGT
ATP + GCYS + GLY --> ADP + PI + RGT
ATP + GLN + TRNAGLN --> AMP + GTRNA + PPI
ATP + GLU + TRNAGLU --> AMP + GLUTRNAGLU + PPI
ALA + ATP + TRNAALA <=> ALATRNA + AMP + PPI
ACACP + 4.0 MALACP + 8.0 NADPH --> 4.0 ACP + C100ACP + 4.0 CO2 + 8.0 NADP
ASP + ATP + TRNAASP --> AMP + ASPTRNAASP + PPI
3.0 MALACP + 6.0 NADPH + PPAACP --> 3.0 ACP + C090ACP + 3.0 CO2 + 6.0 NADP
GLU + OA <=> AKG + ASP
ACP + PPACOA --> COA + PPAACP
NADP + 2.0 RGT <=> NADPH + OGT
ASN + ATP + TRNAASN --> AMP + ASNTRNAASN + PPI
5.0 MALACP + 10.0 NADPH + PPAACP --> 5.0 ACP + C130ACP + 5.0 CO2 + 10.0 NADP
ACACP + 6.0 MALACP + 12.0 NADPH --> 6.0 ACP + C140ACP + 6.0 CO2 + 12.0 NADP
4.0 MALACP + 8.0 NADPH + PPAACP --> 4.0 ACP + C110ACP + 4.0 CO2 + 8.0 NADP
ACACP + 5.0 MALACP + 10.0 NADPH --> 5.0 ACP + C120ACP + 5.0 CO2 + 10.0 NADP
ACACP + 7.0 MALACP + 14.0 NADPH --> 7.0 ACP + C160ACP + 7.0 CO2 + 14.0 NADP
ATP + CYS + GLU --> ADP + GCYS + PI
6.0 MALACP + 12.0 NADPH + PPAACP --> 6.0 ACP + C150ACP + 6.0 CO2 + 12.0 NADP
6.0 MALACP + 11.0 NADPH + PPAACP --> 6.0 ACP + C151ACP + 6.0 CO2 + 11.0 NADP
CYSTEATE --> CO2 + TR
a_3SLALA --> CO2 + HTR
AKG + O2 + TR --> AAA + CO2 + H2SO3 + SUCC
GLU + NAGLUS --> AKG + NAORN
CAP + ORN <=> CITR + PI
NAORN --> AC + ORN
ARGSUCC <=> ARG + FUM
ASP + ATP + CITR <=> AMP + ARGSUCC + PPI
SPRM + a_5MTA --> SAMA + SPRMD
NAD + bAPA --> NADH + bALA
SAM + a_2P14NQ --> PQ + SAH
1.521 ALA + 0.384 ARG + 0.438 ASN + 0.438 ASP + 40.0 ATP + 0.108 CYS + 0.645 GLN + 0.645 GLU + 1.002 GLY + 0.196 HIS + 0.479 ILE + 0.673 LEU + 0.373 LYS + 0.126 MET + 0.283 PHE + 0.392 PRO + 0.407 SER + 0.5 THR + 0.109 TRP + 0.115 TYR + 0.712 VAL --> 40.0 ADP + 40.0 PI + PROTEIN
4.4 ATP + 0.863 DATP + 0.756 DCTP + 0.756 DGTP + 0.863 DTTP --> 4.4 ADP + DNA + 4.4 PI + 3.237 PPI
GLxt --> GLxt_b
2.023 ATP + 0.696 CTP + 0.946 GTP + 0.675 UTP --> 1.25 ADP + 1.25 PI + 3.09 PPI + RNA
0.908 PE + 0.268 PG + 0.155 a_2AG3PE --> PHOSPHOLIPID
0.163 COA + 0.159 FAD + 0.274 FMN + 0.405 MK + 0.188 NAD + 0.168 NADP + 0.739 PYRDX + 0.281 THF --> CAV
MNTxt --> MNTxt_b
46.0 ATP + 0.03 CAV + 0.031 DNA + 0.025 GLYCOGEN + 0.034 LPS + 0.025 PEPTIDO + 0.091 PHOSPHOLIPID + 0.55 PROTEIN + 0.205 RNA --> 46.0 ADP + BIOMASSxt + 46.0 PI
ATP --> ADP + PI
ATP + IMALxt <=> ADP + IMAL + PI
FRUxt + PEP --> F1P + PYR
GL3Pxt --> GL3Pxt_b
GLYxt --> GLYxt_b
NH3xt <=> NH3xt_b
FORMATExt --> FORMATExt_b
GLU + a_3MOP <=> AKG + ILE
DHMP --> a_3MOP
ACACP + 9.0 MALACP + 18.0 NADPH --> 9.0 ACP + C200ACP + 9.0 CO2 + 18.0 NADP
OICAP --> CO2 + a_4MOP
8.0 MALACP + 15.0 NADPH + PPAACP --> 8.0 ACP + C191ACP + 8.0 CO2 + 15.0 NADP
CBHCAP + NAD --> NADH + OICAP
8.0 MALACP + 16.0 NADPH + PPAACP --> 8.0 ACP + C190ACP + 8.0 CO2 + 16.0 NADP
Naxt <=> Naxt_b
IPPMAL <=> CBHCAP
ACACP + 8.0 MALACP + 15.0 NADPH --> 8.0 ACP + C181ACP + 8.0 CO2 + 15.0 NADP
ACCOA + OIVAL --> COA + IPPMAL
ATP + ILE + TRNAILE --> AMP + ILETRNAILE + PPI
ATP + TRNAVAL + VAL --> AMP + PPI + VALTRNAVAL
ATP + C140 + 7.0 COA + 6.0 FAD + 6.0 NAD --> 7.0 ACCOA + AMP + 6.0 FADH2 + 6.0 NADH + PPI
ATP + LEU + TRNALEU --> AMP + LEUTRNA + PPI
ATP + C120 + 6.0 COA + 5.0 FAD + 5.0 NAD --> 6.0 ACCOA + AMP + 5.0 FADH2 + 5.0 NADH + PPI
GLU + a_4MOP <=> AKG + LEU
7.0 MALACP + 13.0 NADPH + PPAACP --> 7.0 ACP + C171ACP + 7.0 CO2 + 13.0 NADP
ACACP + 8.0 MALACP + 16.0 NADPH --> 8.0 ACP + C180ACP + 8.0 CO2 + 16.0 NADP
ACACP + 7.0 MALACP + 13.0 NADPH --> 7.0 ACP + C161ACP + 7.0 CO2 + 13.0 NADP
7.0 MALACP + 14.0 NADPH + PPAACP --> 7.0 ACP + C170ACP + 7.0 CO2 + 14.0 NADP
CO2xt <=> CO2xt_b
DX5P + NADPH --> MDE4P + NADP
G3P + PYR --> CO2 + DX5P
ATP + CDPMDE --> ADP + a_2PCDPMDE
CTP + MDE4P --> CDPMDE + PPI
a_2PCDPMDE --> CMP + MDECPP
ATP + C150 + 7.0 COA + 6.0 FAD + 6.0 NAD --> 6.0 ACCOA + AMP + 6.0 FADH2 + 6.0 NADH + PPACOA + PPI
ATP + C160 + 8.0 COA + 7.0 FAD + 7.0 NAD --> 8.0 ACCOA + AMP + 7.0 FADH2 + 7.0 NADH + PPI
VALxt --> VALxt_b
ATP + C161 + 8.0 COA + 7.0 FAD + 7.0 NAD --> 8.0 ACCOA + AMP + 7.0 FADH2 + 7.0 NADH + PPI
ATP + C180 + 9.0 COA + 8.0 FAD + 8.0 NAD --> 9.0 ACCOA + AMP + 8.0 FADH2 + 8.0 NADH + PPI
ATP + C181 + 9.0 COA + 8.0 FAD + 8.0 NAD --> 9.0 ACCOA + AMP + 8.0 FADH2 + 8.0 NADH + PPI
HPPP + IPP --> HEPPP + PPI
IPP + PPPP --> HPPP + PPI
GGPP + IPP --> PPI + PPPP
FPP + IPP --> GGPP + PPI
GPP + IPP --> FPP + PPI
2.0 NADPH + a_3H3MGCOA --> COA + MVLN + 2.0 NADP
IPP <=> DMPP
DMPP + IPP --> GPP + PPI
MDECPP + NADH --> HMB4PP + NAD
HMB4PP + NADH --> IPP + NAD
DHAP + NADH --> GL3P + NAD
TGL --> 0.052 C120 + 0.182 C140 + 0.05 C150 + 0.39 C160 + 0.24 C161 + 0.01 C180 + 0.076 C181 + DGR
DHAP + NADPH --> GL3P + NADP
NADH + T3 <=> GL + NAD
NADPH + T3 <=> GL + NADP
ATP + GL --> ADP + GL3P
DGR --> AGL + 0.052 C120 + 0.182 C140 + 0.05 C150 + 0.39 C160 + 0.24 C161 + 0.01 C180 + 0.076 C181
HEPPP + IPP --> OPP + PPI
ADP + a_3PG <=> ATP + DGLYCERATE
DGLYCERATE + NADH <=> NAD + T3
LLCT --> HCYS + NH3 + PYR
HCYS + MTHF <=> MET + THF
G3PC --> CHOLINE + GL3P
CTP + PA <=> CDPDG + PPI
ATP + MET + TRNAMET --> AMP + METTRNA + PPI
FTHF + METTRNA --> FMETTRNA + THF
HCYS + a_5MTGLU --> MET + TGLU
SRLH <=> HCYS + RIB
ACOA + GL3P --> COA + a_2AGL3P
CYST --> NH3 + PYR + TCYS
DHAP + DMKH2 <=> DMK + GL3P
H2S + NH3 + PYR --> CYS
DHAP + MKH2 <=> GL3P + MK
SAH <=> AD + SRLH
DHAP + UQH2 <=> GL3P + UQ
ATP + MET --> PI + PPI + SAM
PC --> 0.052 C120 + 0.182 C140 + 0.05 C150 + 0.39 C160 + 0.24 C161 + 0.01 C180 + 0.076 C181 + a_2AG3PC
ATP + DGR --> ADP + PA
AGL3P + 0.052 C120ACP + 0.182 C140ACP + 0.05 C150ACP + 0.39 C160ACP + 0.24 C161ACP + 0.01 C180ACP + 0.076 C181ACP --> ACP + PA
0.052 C120ACP + 0.182 C140ACP + 0.05 C150ACP + 0.39 C160ACP + 0.24 C161ACP + 0.01 C180ACP + 0.076 C181ACP + GL3P --> ACP + AGL3P
GLN + PRPP --> GLU + PPI + PRAM
ACCOA + SER <=> ASER + COA
ASER + H2S --> AC + CYS
MPYR + NADH --> NAD + a_3MLAC
ASER + HO3S2 + RTHIO --> AC + CYS + H2SO3 + OTHIO
ASER + HO3S2 --> AC + SSLCYS
AKG + CYSTEATE <=> GLU + a_3SPYR
AKG + a_3SLALA --> GLU + a_3SFPYR
DGLUxt --> DGLUxt_b
CDPDG + SER <=> CMP + PS
PS --> CO2 + PE
SER --> a_2AA
PS --> 0.052 C120 + 0.182 C140 + 0.05 C150 + 0.39 C160 + 0.24 C161 + 0.01 C180 + 0.076 C181 + a_2AG3PS
GLU + MPYR --> AKG + CYS
G3PE --> ETHA + GL3P
PE --> 0.052 C120 + 0.182 C140 + 0.05 C150 + 0.39 C160 + 0.24 C161 + 0.01 C180 + 0.076 C181 + a_2AG3PE
ATP + CYS + TRNACYS --> AMP + CYSTRNACYS + PPI
PGP --> PG + PI
CDPDG + GL3P <=> CMP + PGP
ATP + R5P <=> AMP + PRPP
CDPDG + PG --> CL + CMP
a_3HIVCOA <=> a_3MCCOA
a_2MP2ECOA --> a_3HIBCOA
COA + S2MBDHL --> DLIPO + a_2MBCOA
FAD + a_3MBCOA --> FADH2 + a_3MCCOA
LIPO + OIVAL --> CO2 + S2MPDHL
COA + S2MPDHL --> DLIPO + a_2MPPACOA
HIBUT + NAD --> NADH + a_3OPP
COA + S3MBDHL --> DLIPO + a_3MBCOA
FTHF + GAR --> FGAR + THF
ATP + GLY + PRAM <=> ADP + GAR + PI
ASP + GTP + IMP --> ASUC + GDP + PI
PRFICA <=> IMP
AICAR + FTHF <=> PRFICA + THF
SAICAR <=> AICAR + FUM
ASP + ATP + CAIR <=> ADP + PI + SAICAR
AIR + ATP + CO2 --> ADP + CAIR + PI
ATP + FGAM --> ADP + AIR + PI
ATP + HCO3 + a_3MCCOA --> ADP + PI + a_3MGCOA
ATP + FGAR + GLN --> ADP + FGAM + GLU + PI
a_3H2MBCOA --> a_2MB2ECOA
DHMVA --> OIVAL
GLU + OIVAL <=> AKG + VAL
ALA + OIVAL --> PYR + VAL
OBUT + a_2HETPP --> ABUT + THMPP
NAD + a_3H2MBCOA <=> NADH + a_2MAACCOA
MMSA + NAD --> MM + NADH
COA + a_2MAACCOA --> ACCOA + PPACOA
ACLAC + NADPH --> DHMVA + NADP
HIBUT + NAD <=> MMSA + NADH
NAGAxt --> NAGAxt_b
ASUC <=> AMP + FUM
ATP + GLN + XMP --> AMP + GLU + GMP + PPI
IMP + NAD --> NADH + XMP
ADN --> INS + NH3
ATP + GSN <=> ADP + GMP
DA <=> DIN + NH3
a_23cAMP --> a_3AMP
ABUT + NADPH --> DHMP + NADP
GMP + NADPH --> IMP + NADP + NH3
ATP + INS <=> ADP + IMP
a_23cGMP --> a_3GMP
DAMP <=> DA + PI
DGMP <=> DG + PI
DIN + PI --> DR1P + HYXN
DATP + PYR <=> DADP + PEP
GTP + PYR <=> GDP + PEP
DGDP + PEP --> DGTP + PYR
DTxt --> DTxt_b
IMP --> INS + PI
AMP --> ADN + PI
XMP --> PI + XTSINE
GMP --> GSN + PI
ARGxt --> ARGxt_b
PRPP + QA --> CO2 + NACN + PPI
NACN --> NACD + PI
VB12xt <=> VB12xt_b
O2 + PYRDX <=> H2O2 + PL
PDLA5P --> PDLA + PI
ATP + PDLA --> ADP + PDLA5P
O2 + PDLA5P --> H2O2 + NH3 + PL5P
DHAP + IASP --> PI + QA
ASP + O2 --> H2O2 + IASP
ACxt --> ACxt_b
ASP + FUM --> IASP + SUCC
NH3 + O2 + PL <=> H2O2 + PDLA
GLNxt --> GLNxt_b
MLTxt --> MLTxt_b
FUMxt --> FUMxt_b
AKGxt --> AKGxt_b
Hxt <=> Hxt_b
ALAxt --> ALAxt_b
THRxt --> THRxt_b
METxt --> METxt_b
DALAxt --> DALAxt_b
PROxt --> PROxt_b
TYRxt --> TYRxt_b
NO3xt <=> NO3xt_b
IMALxt --> IMALxt_b
ATP + BT --> B5AMP + PPI
AHHMP + PABA --> DHPT
AHHMP + ATP --> AHHMD + AMP
CHOR + GLN --> ADCHOR + GLU
ADCHOR --> PABA + PYR
AHHMD + PABA --> DHPT + PPI
A_C_ + B5AMP --> AMP + H_C_
GTP --> AHTD + FORMATE
AHTD --> DHP + PI + PPI
DHP --> AHHMP + GLAL
DHF + NADPH --> NADP + THF
ATP + DHPT + GLU --> ADP + DHF + PI
XANxt --> XANxt_b
AHTD --> H5P3O10 + PYTHP
DHBPT + NADH <=> NAD + THBPT
FL + NADPH --> NADP + THF
ATP + GLU + THF <=> ADP + PI + THFG
DHF + NADP <=> FL + NADPH
FL + NADH --> NAD + THF
DHF + NADH --> NAD + THF
DHF + NAD <=> FL + NADH
DHBPT + NADPH <=> NADP + THBPT
METHF --> FTHF
GAR + METHF --> FGAR + THF
DUxt --> DUxt_b
METHF --> a_5FTHF
METTHF + NADP <=> METHF + NADPH
METHF <=> FTHF
METTHF + NADPH --> MTHF + NADP
FADH2 + METTHF <=> FAD + MTHF
DUMP + METTHF <=> DHF + DTMP
FTHF <=> FORMATE + THF
4.0 PBG --> HMB + 4.0 NH3
2.0 ALAV --> PBG
GSA --> ALAV
GTRNA + NADPH --> GSA + NADP
DGxt --> DGxt_b
ADPG --> ADP + GLYCOGEN
GLYCOGEN + PI --> G1P
MLTHPT + PI <=> G1P + MLTHX
MLT + MLTTR --> GLC + MLTTTR
SUCxt --> SUCxt_b
MLTPT + PI <=> G1P + MLTTTR
MLTHX + PI <=> G1P + MLTPT
NAD + PC2 --> NADH + SHCL
MLT + MLTHX --> GLC + MLTHPT
SHCL --> SHEME
IMAL --> 2.0 GLC
HMB --> UPRG
MLT + MLTTTR --> GLC + MLTPT
2.0 SAM + UPRG --> PC2 + 2.0 SAH
MLT + MLTPT --> GLC + MLTHX
UPRG --> 4.0 CO2 + CPP
CPP + 2.0 SAM --> 2.0 CO2 + 2.0 DA + 2.0 MET + PPHG
1.5 O2 + PPHG --> PPIX
PPIX --> PTH
ATP + CIDA --> ACDA + PI + PPI
ACDA + 4.0 ATP + 4.0 GLN --> ACHA + 4.0 ADP + 4.0 GLU + 4.0 PI
CPP + O2 --> 2.0 CO2 + PPHG
ADCBAP + GTP --> AGDPCBA + PPI
ATP + G1P --> ADPG + PPI
ACHA + ATP + D1AP2OOP --> ADCBAP + ADP + PI
LXYLULOSE5P --> LRIBULOSE5P
ACHA + a_1AP2O --> ADCBA
DGLUCL + NAD <=> DGLUCA + NADH
ADCBA + GTP --> ADCBAP + GDP
NAD + a_2D3DDX <=> NADH + a_5H24DP
ADCBA + ATP --> ADCBAP + ADP
a_3DG6P --> CO2 + LXYLULOSE5P
a_3KL <=> a_3KBDG + bDGLC
LACTOSE + PI --> L6P
NADP + a_3KBDG <=> NADPH + bGLAC
ATP + T6P <=> ADP + T16B
LACTOSE --> GLAC + GLC
CHOR <=> PYR + a_4HB
OPP + a_4HB --> PPI + a_3OP4HB
2.0 ACIIIA + NADH --> 2.0 CIIA + NAD
CHOR <=> ICHOR
N15PADRDMB --> ARBZ + PI
AGDPCBA + ARBZ --> CBCO + GMP
G6GG --> GLAC + MELI
GALACTINOL --> GLAC + MI
NADPH + O2 + a_2OP6MP --> NADP + a_2OP6M14BQ
MELT <=> GLAC + SOT
SAM + a_2OP6HP --> SAH + a_2OP6MP
GGL <=> GL + GLAC
NADPH + O2 + a_2OPP --> NADP + a_2OP6HP
EPM <=> GLAC + MAN
a_3OP4HB --> CO2 + a_2OPP
MELI --> GLAC + GLC
STACHYOSE --> GLAC + RAF
RAF --> GLAC + SUC
G1P + UTP <=> PPI + UDPG
GAL1P + UTP <=> PPI + UDPGAL
SAM + a_2OP6M14BQ --> SAH + a_2OP3M6M14BQ
NADPH + O2 + a_2OP3M6M14BQ --> NADP + a_2OP3M5H6M14BQ
SAM + a_2OP3M5H6M14BQ --> SAH + UQ
AKG + ICHOR --> CO2 + PYR + SHCHC
SHCHC --> OSB
ATP + COA + OSB --> AMP + OSBCOA + PPI
OSBCOA --> COA + DHN
DMK + SAM --> MKH2 + SAH
MNT1P + NAD --> F6P + NADH
DHN + OPP --> CO2 + DMK + PPI
GTP + MAN1P <=> GDPMAN + PPI
NADP + S6P <=> NADPH + SB1P
DHN + PPP --> CO2 + PPI + a_2P14NQ
F2P <=> FRU + PI
GAL1P + UDPG <=> G1P + UDPGAL
CHOLINExt --> CHOLINExt_b
ATP + GLAC --> ADP + GAL1P
UDPG <=> UDPGAL
F1P --> DHAP + T3
MAN6P <=> MAN1P
MAN6P <=> F6P
KDG <=> DMAN
KDG + NAD <=> DDOH + NADH
DGALAC --> DTAGA
D6PGC --> KDPG
ATP + F1P --> ADP + FDP
2.0 NAD + UDPG <=> 2.0 NADH + UDPGLUC
DGLUC <=> DFRUC
ASNxt --> ASNxt_b
DMAN + NAD <=> DFRUC + NADH
ATP + GLUC --> ADP + D6PGC
ATP + KDG --> ADP + KDPG
GLCxt <=> GLCxt_b
RL5P <=> R5P
ATP + HIS + TRNAHIS --> AMP + HISTRNAHIS + PPI
HIS --> NH3 + UC
HISOL + 2.0 NAD --> HIS + 2.0 NADH
HIS + SAM --> NMHIS + SAH
GLU + IMACP --> AKG + HISOLP
HISOLP --> HISOL + PI
ATP + DRIB --> ADP + DR5P
DR1P <=> DR5P
G3P + S7P <=> E4P + F6P
DR5P --> ACAL + G3P
R5P + X5P <=> G3P + S7P
E4P + X5P <=> F6P + G3P
ATP + RIB --> ADP + R5P
SERxt --> SERxt_b
R1P <=> R5P
DTxt + Hxt --> DT
DGxt + Hxt --> DG
DCxt + Hxt --> DC
DAxt + Hxt --> DA
CYTDxt + Hxt --> CYTD
ADNxt + Hxt --> ADN
GLxt <=> GL
KDPG --> G3P + PYR
DIMGP --> IMACP
GLN + PRLP --> AICAR + DIMGP + GLU
PRFP --> PRLP
PRBAMP --> PRFP
Hxt + URIxt --> URI
GSNxt + Hxt --> GSN
DUxt + Hxt --> DU
HYDROXYAKG --> GLX + PYR
ATP + PRPP --> PPI + PRBATP
PRBATP --> PPI + PRBAMP
NADP + a_4AB --> GABA + NADPH
PTRC + SAMA --> SPRMD + a_5MTA
HCNS --> GABA + HIS
a_5MTA --> AD + a_5MDR
MAL + NAD <=> NADH + OA
PIxt <=> PIxt_b
G6P + NADP --> D6PGL + NADPH
G6P + NAD --> D6PGL + NADH
D6PGL --> D6PGC
FAD + SUCC --> FADH2 + FUM
FUM + MKH2 --> MK + SUCC
DMKH2 + FUM --> DMK + SUCC
FUM <=> MAL
Hxt + XANxt --> XAN
RL5P <=> X5P
CTxt + Hxt --> CT
D6PGC + NADP --> CO2 + NADPH + RL5P
ATP + VB12xt --> ADP + PI + VB12
Hxt + URAxt --> URA
AKG + E4HGLU --> GLU + HYDROXYAKG
N4AAB + NAD --> NADH + a_4AABUT
HYDROXYAKG <=> GLX + PYR
E4P + PEP --> PI + a_3DDAH7P
a_3DDAH7P --> DQT + PI
2.0 O2 + 2.0 a_3HAN --> CVN + 2.0 H2O2
COA + NAD + a_2OAD --> CO2 + GLUTCOA + NADH
AC + ATP + COA <=> ACCOA + AMP + PPI
ACAL + NAD --> AC + NADH
DLIPO + NAD --> LIPO + NADH
ICITxt --> ICITxt_b
CIT <=> ICIT
ICIT + NADP --> AKG + CO2 + NADPH
ACAL + NADH <=> ETH + NAD
ACCOA + OA --> CIT + COA
ADP + PI + SUCCOA <=> ATP + COA + SUCC
COA + SDLIPO --> DLIPO + SUCCOA
AKG + LIPO --> CO2 + SDLIPO
DPHE --> NH3 + PHPYR
O2 + PHPYR --> CO2 + a_2HPA
I3AA + NAD --> I3AC + NADH
NAD + a_5HIAA --> NADH + a_5HIAC
ATP + TRNATRP + TRP --> AMP + PPI + TRPTRNATRP
TRP --> INDOLE + NH3 + PYR
AKG + TYR <=> GLU + a_4HPP
O2 + a_4HPP --> CO2 + HOMOGEN
a_4MAAC --> a_4FAAC
NAD + a_34DHPEG <=> NADH + a_34DHMA
AKG + PHE <=> GLU + PHPYR
DHAP <=> G3P
G3P + NAD + PI <=> NADH + a_13PDG
ADP + a_13PDG <=> ATP + a_3PG
ADP + a_13PDG --> ATP + a_3PG
a_3PG <=> a_2PG
a_2PG <=> PEP
NAD + SLAC <=> NADH + PYR
ADP + PEP --> ATP + PYR
ADLIPO + COA --> ACCOA + DLIPO
LIPO + PYR --> ADLIPO + CO2
UC --> a_4I5P
NFGLU --> FA + GLU
a_4I5P --> NFGLU
a_5CM2HM --> a_5C2O3E
I4AA + NAD --> I4AC + NADH
G6P <=> F6P
A6P --> HQ + bDG6P
G6P <=> bDG6P
GLC <=> bDGLC
LIPO + a_2OAD --> CO2 + SGDHL
ATP + LYS + TRNALYS --> AMP + LYSTRNA + PPI
GTP --> PPI + cGMP
MDAPIM --> CO2 + LYS
ATP --> PPI + cAMP
DAPIM <=> MDAPIM
SDAPIM --> DAPIM + SUCC
GLU + SAOPIM --> AKG + SDAPIM
SUCCOA + TDHDP --> COA + SAOPIM
DHDP + NADH --> NAD + TDHDP
DHDP + NADPH --> NADP + TDHDP
ASPSA + PYR --> DHDP
HYXN + PRPP --> IMP + PPI
PRPP + XAN --> PPI + XMP
AD + PRPP --> AMP + PPI
GN + PRPP --> GMP + PPI
ATP + DIDP <=> ADP + DITP
AICAR + PPI <=> PRPP + a_5A4IC
ATP + DGMP <=> ADP + DGDP
ATP + IDP <=> ADP + ITP
FDP <=> DHAP + G3P
ATP + F6P --> ADP + FDP
FDP --> F6P + PI
bDG6P <=> F6P
G6P <=> G1P
ATP + NACN --> NAAD + PPI
NAC + PRPP --> NACN + PPI
NAC + R1P --> NACD + PI
ATP + GLN + NAAD --> AMP + GLU + NAD + PPI
ATP + NACD --> ADP + NACN
NAMN --> NAMD + PI
NAM --> NAC + NH3
NAM + R1P --> NAMD + PI
ATP + NAD --> ADP + NADP
NADH + NADP --> NAD + NADPH
Hxt + SER <=> SERxt
ATP + SERxt --> ADP + PI + SER
Hxt + PRO <=> PROxt
ATP + PROxt --> ADP + PI + PRO
Hxt + PROxt --> PRO
Naxt + PROxt --> Na + PRO
Hxt + METxt --> MET
Hxt + PHE <=> PHExt
ATP + PHExt --> ADP + PHE + PI
Hxt + PHExt --> PHE
CYTDxt --> CYTDxt_b
2.0 PYR --> ACLAC + CO2
NAD + NADPH <=> NADH + NADP
NADP --> NAD + PI
ATP + PNTO --> ADP + a_4PPNTO
ATP + PANT + bALA --> AMP + PNTO + PPI
DHPANT + NADPH --> NADP + PANT
METTHF + OIVAL --> DHPANT + THF
L1P3H5C + NADH --> NAD + a_4HPRO
FAD + a_4HPRO --> FADH2 + L1P3H5C
CTP + CYS + a_4PPNTO --> CMP + PPI + a_4PPNCYS
ATP + PRO + TRNAPRO --> AMP + PPI + PROTRNAPRO
ATP + PTT --> ADP + a_4PPNTE
FAD + PRO --> FADH2 + P5C
ATP + NPCYS --> ADP + a_4PPNCYS
E4HGLU + NAD <=> NADH + a_4HGLUSA
ATP + DADP <=> ADP + DATP
L1P3H5C + NADP --> E4HGLU + NADPH
ADP + RTHIO --> DADP + OTHIO
L1P3H5C + NAD --> E4HGLU + NADH
AMP + ATP <=> 2.0 ADP
L1P3H5C + NADPH --> NADP + a_4HPRO
ppGpp <=> GDP + PPI
Hxt + TYR <=> TYRxt
GDP + RTHIO --> DGDP + OTHIO
ATP + TYRxt --> ADP + PI + TYR
ATP + DGDP <=> ADP + DGTP
ATP + TRPxt --> ADP + PI + TRP
ATP + GMP <=> ADP + GDP
Hxt + TRPxt --> TRP
ATP + GDP <=> ADP + GTP
NADP + P5C --> GLU + NADPH
GLUGSAL + NAD --> GLU + NADH
Hxt + TYRxt --> TYR
ARIB --> AMP + R5P
ATP + RTHIO --> DATP + OTHIO
Hxt + SERxt --> SER
Hxt + THRxt --> THR
Hxt + TRP <=> TRPxt
Hxt + THR <=> THRxt
ATP + THRxt --> ADP + PI + THR
ATP + a_4PPNTE --> DPCOA + PPI
a_4PPNCYS --> CO2 + a_4PPNTE
NAD + P5C --> GLU + NADH
AACP + COA --> ACP + PAP
ATP + DPCOA --> ADP + COA
TRPxt --> TRPxt_b
PTT --> CA + PNTO
ACP --> AACP + a_4PPNTE
AONA + SAM <=> DANNA + SAMOB
ALA + CHCOA <=> AONA + CO2 + COA
DTB + S --> BT
ARG + SUCCOA <=> COA + N2SUCCARG
ATP + CO2 + DANNA <=> ADP + DTB + PI
ARG --> CITR + NH3
ORN --> CO2 + PTRC
ARG + ATP + TRNAARG <=> AMP + ARGTRNAARG + PPI
ARG --> AGMATINE + CO2
AMP + PPI <=> AD + PRPP
AGMATINE --> PTRC + UREA
N2SUCCGLU --> GLU + SUCC
DA + PI <=> AD + DR1P
N2SUCCGLU5SA + NAD <=> N2SUCCGLU + NADH
DIN + PI <=> DR1P + HYXN
ATP + PTRCxt --> ADP + PI + PTRC
DG + PI <=> DR1P + GN
ATP + SPRMDxt --> ADP + PI + SPRMD
HYXN + R1P <=> INS + PI
ATP + UREAxt --> ADP + PI + UREA
AD + R1P <=> ADN + PI
CHOLINExt + Hxt --> CHOLINE
GN + R1P <=> GSN + PI
R1P + XAN <=> PI + XTSINE
DGTP --> DG + H5P3O10
ATP + GTP --> AMP + pppGpp
DLIPO + GLUTCOA <=> COA + SGDHL
Hxt + VAL <=> VALxt
ATP + VALxt --> ADP + PI + VAL
Hxt + VALxt --> VAL
HSER + Hxt <=> HSERxt
ATP + ORNxt --> ADP + ORN + PI
ORN + PTRCxt <=> ORNxt + PTRC